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Details

viral hepatitis
drugs
6
Pharmacology
Professional
01/30/2011

Additional Pharmacology Flashcards

 


 

Cards

Term
Lamivudine(Epivir-HBV)
Definition
Cytosine nucleoside analogue. Inhi DNA syn and replication of HBV. Resistance is biggest concern
Term
Tenofovir (Viread)
Definition
Nucleoside RT inhibitor. Inhi HIV and HBV replication
nephrotoxic
Term
Entecavir (Baraclude)
Definition
For HBV-resistant. Guanosine nucleoside analogue, Inh HBV DNA.
BBW: develope resistance to HIV nucleoside RT inhibitor-NO monotherapy in coinfected with HIV and HBV
Term
Adefovir (Hepsera)
Definition
Prodrug. Inhibit HBV RT and DNA pol.
Effective against lamivudine resistant HBV
Term
Telbivudine (Tyzeka)
Definition
L-nucleoside analogue. inh syn of HBV DNA
Term
Ribavirin (Rebetol, Copegus, Ribapak)
Definition
dose based on wt; inh RNA replication; NO monotherapy; Pregnancy test-2form contraception
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