Term
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Definition
Class: vasodilator, nitrate
Mechanism: increase nitric oxide level in body, increases guanylate cylase activity -> increase cGMP concentration -> promote vasodilation; reduce preload and afterload of LV
Indication: angina, CHF, Raynaud's
Adverse effects: tolerance, orthostatic hypotension, tachycardia, HA, dizziness, flushing, syncope |
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|
Term
|
Definition
Class: vasodilator, nitrate
Mechanism: increase nitric oxide level in body, increases guanylate cylase activity -> increase cGMP concentration -> promote vasodilation; reduce preload and afterload of LV
Indication: angina, CHF, Raynaud's
Adverse effects: tolerance, orthostatic hypotension, tachycardia, HA, dizziness, flushing, syncope |
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|
Term
|
Definition
Class: vasodilator, Ca++ ch. blocker, type I (vasculature and electrical effects)
Mechanism: calcium channel blockade, limit calcium entry into cell through membrane channels
Indication: angina, HTN
Adverse effects: CARDIODEPRESSION (dec. contractility), hypotension, AV block, peripheral edema, HA, constipation |
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|
Term
|
Definition
Class: vasodilator, Ca++ ch. blocker, type I (vasculature and electrical effects)
Mechanism: calcium channel blockade, limit calcium entry into cell through membrane channels
Indication: angina, HTN
Adverse effects: hypotension, peripheral edema, AV block, CARDIODEPRESSION |
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|
Term
|
Definition
Class: vasodilator, Ca++ ch. blocker, type II (vasculature only)
Mechanism: calcium channel blockade, limit calcium entry into cell through membrane channels
Indication: angina, HTN
Adverse effects: hypotension, HA, peripheral edema |
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|
Term
|
Definition
Class: vasodilator, beta-blocker
Mechanism: increased diastolic perfusion, less exercise vasoconstriction, dec. HR, dec. contractility
Indication:
Contraindication: AV conduction abnormalities, asthma, COPD, depression
Adverse effects: bradycardia, AV block, negative inotrophy, bronchoconstriction, depression, nightmares, sexual dysfunction |
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Term
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Definition
Class: vasodilator,
Mechanism: inhibits type 5 phosphodiesterase
Indication: erectile dysfunction
Contraindication: CO-ADMIN w/ NITRATES
Adverse effects: hypotension, flushing, dyspepsia, dose-related abnormal vision
Pharm - CYP450 inducer |
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|
Term
|
Definition
Class: vasodilator, nitrate
Mechanism: increase nitric oxide level in body, increases guanylate cylase activity -> increase cGMP concentration -> promote vasodilation; reduce preload and afterload of LV
Indication: angina, CHF, Raynaud's
Adverse effects: tolerance, orthostatic hypotension, tachycardia, HA, dizziness, flushing, syncope |
|
|
Term
|
Definition
Class: vasodilator, nitrate
Mechanism: increase nitric oxide level in body, increases guanylate cylase activity -> increase cGMP concentration -> promote vasodilation; reduce preload and afterload of LV
Indication: angina, CHF, Raynaud's
Adverse effects: tolerance, orthostatic hypotension, tachycardia, HA, dizziness, flushing, syncope |
|
|
Term
|
Definition
Class: vasodilator, Ca++ ch. blocker, type I (vasculature and electrical effects)
Mechanism: calcium channel blockade, limit calcium entry into cell through membrane channels
Indication: angina, HTN
Adverse effects: CARDIODEPRESSION (dec. contractility), hypotension, AV block, peripheral edema, HA, constipation |
|
|
Term
|
Definition
Class: vasodilator, Ca++ ch. blocker, type I (vasculature and electrical effects)
Mechanism: calcium channel blockade, limit calcium entry into cell through membrane channels
Indication: angina, HTN
Adverse effects: hypotension, peripheral edema, AV block, CARDIODEPRESSION |
|
|
Term
|
Definition
Class: vasodilator, Ca++ ch. blocker, type II (vasculature only)
Mechanism: calcium channel blockade, limit calcium entry into cell through membrane channels
Indication: angina, HTN
Adverse effects: hypotension, HA, peripheral edema |
|
|
Term
|
Definition
Class: vasodilator, beta-blocker
Mechanism: increased diastolic perfusion, less exercise vasoconstriction, dec. HR, dec. contractility
Indication:
Contraindication: AV conduction abnormalities, asthma, COPD, depression
Adverse effects: bradycardia, AV block, negative inotrophy, bronchoconstriction, depression, nightmares, sexual dysfunction |
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|
Term
|
Definition
Class: vasodilator,
Mechanism: inhibits type 5 phosphodiesterase
Indication: erectile dysfunction
Contraindication: CO-ADMIN w/ NITRATES
Adverse effects: hypotension, flushing, dyspepsia, dose-related abnormal vision
Pharm - CYP450 inducer |
|
|
Term
|
Definition
Class: vasodilator, nitrate
Mechanism: increase nitric oxide level in body, increases guanylate cylase activity -> increase cGMP concentration -> promote vasodilation; reduce preload and afterload of LV
Indication: angina, CHF, Raynaud's
Adverse effects: tolerance, orthostatic hypotension, tachycardia, HA, dizziness, flushing, syncope |
|
|
Term
|
Definition
Class: vasodilator, nitrate
Mechanism: increase nitric oxide level in body, increases guanylate cylase activity -> increase cGMP concentration -> promote vasodilation; reduce preload and afterload of LV
Indication: angina, CHF, Raynaud's
Adverse effects: tolerance, orthostatic hypotension, tachycardia, HA, dizziness, flushing, syncope |
|
|
Term
|
Definition
Class: vasodilator, Ca++ ch. blocker, type I (vasculature and electrical effects)
Mechanism: calcium channel blockade, limit calcium entry into cell through membrane channels
Indication: angina, HTN
Adverse effects: CARDIODEPRESSION (dec. contractility), hypotension, AV block, peripheral edema, HA, constipation |
|
|
Term
|
Definition
Class: vasodilator, Ca++ ch. blocker, type I (vasculature and electrical effects)
Mechanism: calcium channel blockade, limit calcium entry into cell through membrane channels
Indication: angina, HTN
Adverse effects: hypotension, peripheral edema, AV block, CARDIODEPRESSION |
|
|
Term
|
Definition
Class: vasodilator, Ca++ ch. blocker, type II (vasculature only)
Mechanism: calcium channel blockade, limit calcium entry into cell through membrane channels
Indication: angina, HTN
Adverse effects: hypotension, HA, peripheral edema |
|
|
Term
|
Definition
Class: vasodilator, beta-blocker
Mechanism: increased diastolic perfusion, less exercise vasoconstriction, dec. HR, dec. contractility
Indication:
Contraindication: AV conduction abnormalities, asthma, COPD, depression
Adverse effects: bradycardia, AV block, negative inotrophy, bronchoconstriction, depression, nightmares, sexual dysfunction |
|
|
Term
|
Definition
Class: vasodilator,
Mechanism: inhibits type 5 phosphodiesterase
Indication: erectile dysfunction
Contraindication: CO-ADMIN w/ NITRATES
Adverse effects: hypotension, flushing, dyspepsia, dose-related abnormal vision
Pharm - CYP450 inducer |
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