Term
Theophylline
Mech?
Use?
Tox? |
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Definition
Inhibits PDE, raising cAMP, causes bronchodilation.
Anti-asthma, but narrow therapeutic index.
Cardiotoxicity, neurotoxicity.
(blocks actions of adenosine) |
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Term
Cromolyn Sulfate
Mech?
Use?
Tox? |
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Definition
Prevents mast cell degranulation.
Asthma prophylaxis (not acute tx).
Rare toxicity |
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Term
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Definition
5-lipoxygenase inhibitor; blocks conversion of arachidonic acid to leukotrienes
Asthma prophylaxis |
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Term
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Definition
Block leukotriene D4 receptors
Asthma, esp. aspirin induced asthma |
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Term
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Definition
Block leukotriene D4 receptors
Asthma, esp. aspirin induced asthma |
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Term
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Definition
Removes excess sputum, does not remove cough reflex
Expectorant |
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Term
N-acetylcysteine
Mech?
Use? |
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Definition
Mucolytic
Loosen mucus plugs in CF pts
(also used in acetominophen overdose) |
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Term
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Definition
Endothelin-1 receptor antagonist
Pulmonary HTN, decreases pulm. vasc. resistance |
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Term
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Definition
Anti-IgE antibody, prevents IgE binding to mast cells.
Prophylaxis for allergen induced asthma attack. |
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Term
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Definition
1st generation H1 blocker
Allergy, motion sickness, sleep aid
Sedation, anti-muscarinic, anti-alpha-adrenergic |
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Term
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Definition
1st generation H1 blocker
Allergy, motion sickness, sleep aid
Sedation, anti-muscarinic, anti-alpha-adrenergic |
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Term
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Definition
1st generation H1 blocker
Allergy, motion sickness, sleep aid
Sedation, anti-muscarinic, anti-alpha-adrenergic |
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Term
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Definition
2nd gen H1 blocker.
Allergy
Less CNS entry, so far less sedating than 1st gen |
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Term
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Definition
2nd gen H1 blocker.
Allergy
Less CNS entry, so far less sedating than 1st gen |
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Term
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Definition
2nd gen H1 blocker.
Allergy
Less CNS entry, so far less sedating than 1st gen |
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Term
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Definition
2nd gen H1 blocker.
Allergy
Less CNS entry, so far less sedating than 1st gen |
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