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USMLE Step 1 Heme/Onc
Heme onc junk :(
7
Medical
Professional
04/23/2013
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Term
t[9;22]
 Definition
bcr-abl, CML
Term
t[15;17]
 Definition
AML, M3 type (all-trans retinoic acid responsive)
Term
t[8;14]
 Definition
c-myc, Burkitt's lymphoma; non-hodgkins
Term
t[11;14]
 Definition
cyclin-D1 activationl Mantle cell lymphoma
Term
t[14;18]
 Definition
bcl-2 activation; Follicular lymphoma
Term
t[8;21]
 Definition
AML, down's syndrome
Term
JAK2
 Definition
constitutive tyrosine kinase, STAT, myeloproliferative d/o (PCV, essential thrombocytosis, primary myelofibrosis
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