Term
| Htn drugs contraindicated for pregnancy ? |
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Definition
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Term
| Drug to give for htn , post-MI ? |
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Definition
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Term
| Drugs to give for htn with angina ? |
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Definition
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Term
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Definition
An endothelin receptor antagonist
Used to trt pulmonary htn |
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Term
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Definition
Bosentan
Prostacyclin (PGI-2) (Epoprostenol)
Sildenafil (Viagra) |
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Term
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Definition
Is a cardiac glycoside and does not increase survival
Inhibits cardiac Na+K+ATPase...results in increase in intracellular Na+...increase Ca2+...is an inotrope so increases contractility
Also used in arrhythmias |
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Term
| Side-effects of Digoxin ? |
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Definition
Anorexia, nausea
Later can get disorientation and **visual halos**, and in toxic doses can get arrhythmias |
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Term
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Definition
| A PDE-3 inhibitor used for intermittent claudication |
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Term
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Definition
| Recombinant BNP used to trt acutely decompensated CHF, by increasing cGMP and causing vasodilation |
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Term
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Definition
Definitive treatment is catheter ablation / cardioversion
Drug trt can be Procainamide or Amiodarone |
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Term
| Do not use inotropic agents to trt ? |
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Definition
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Term
| DOC for Raynaud's disease ? |
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Definition
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Term
| MOA of Sildenafil (Viagra) ? |
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Definition
| PDE-5 inhibitor...increases cGMP...vasodilation...increases blood flow and erection |
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Term
| Vasospastic angina can be trted with ? |
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Definition
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Term
| What drug can cause coronary vasospasm ? |
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Definition
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Term
| What diuretic class works in the early DCT ? |
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Definition
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Term
| What effects do loop diuretics and thiazide diuretics have in common ? |
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Definition
| Hyperuricemia, hypokalemia, metabolic alkalosis |
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Term
| Ethacrynic acid is what type of diuretic ? |
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Definition
Loop diuretic
Side-effect is ototoxicity
**Does not react against Sulfonamide-containing drugs** |
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Term
| How is loop diff. from thiazide diuretic ? |
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Definition
"Loops lose Ca2+"
Are hypocalcemic...
Also hypomagnesima |
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Term
| DOC for acute pulmonary edema ? |
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Definition
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Term
| DOC for nephrogenic diabetes insipidus ? |
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Definition
Thiazide diuretics (also these drugs work by inhibiting Na+/Cl- transport)
And used for calcium stones, htn, CHF |
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Term
| Side-effects of Spironolactone ? |
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Definition
Antiandrogen (female hirsutism)
Hyperkalemia and acidosis |
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Term
| Spirinolactone is K+ sparing diuretic and ? |
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Definition
| aldosterone-receptor antagonist |
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