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Use and Effects of Drugs
Final
250
Health Care
Undergraduate 3
12/06/2013

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Term
Alter perceptions while allowing the user to remain in communication with the present world
Definition
Classical phantastica
Term
Keep present in real world but alter perception
Definition
Classical phantastica
Term
Produce more mental confusion, greater clouding of consciousness, and a loss of touch with reality
Definition
Deliriants
Term
Loose real world aspects
Definition
Deliriants
Term
LSD Synthesized by
Definition
Dr. Albert Hofmann of Sandoz Laboratories in Switzerland
Term
Various militaries, including the US military, experimented extensively with
Definition
LSD
Term
sponsored research was poorly done and violated many ethical codes
Definition
Army and CIA LSD research
Term
Experiments by psychologist Timothy Leary on Harvard graduate students
Definition
LSD
Term
LSD Experiments by psychologist_____on Harvard graduate students
Definition
Timothy Leary
Term
started a religion, the League of Spiritual Discovery, with LSD as the sacrament
Definition
Timothy Leary
Term
Religion started by Timothy Leary with LSD as the sacrament
Definition
League of Spiritual Discovery
Term
LSD use peaked in
Definition
1967 and 1968
Term
odorless, colorless, tasteless, and one of the most potent psychochemicals known
Definition
LSD
Term
No physical dependency with
Definition
Hallucinogens
Term
LSD half life is about
Definition
three hours
Term
Drug metabolized by the liver
Definition
LSD
Term
LSD tolerance develops
Definition
Tolerance develops rapidly, within three to four days of daily doses
Term
Cross-tolerance occurs among
Definition
LSD, mescaline, and psilocybin
Term
he LSD molecule resembles the chemical structure of
Definition
serotonin
Term
LSD 'trips' typically last
Definition
six to nine hours
Term
Drug where Effects depend on dose
Definition
Psilocybin
Term
Small amount create small reactions- relaxation effects
Definition
Psilocybin
Term
Larger amounts create more negative and larger reactions
Definition
Psilocybin
Term
Native American Church uses this drug
Definition
Peyote
Term
peyote use incorporated into its ceremonies
Definition
Native American Church
Term
Native American Church given permission by the Federal government to use
Definition
Peyote during certain ceremonies while on their reservations
Term
Peyote use (on reservations)
Definition
In religious ceremonies
As a treatment for illness
Worn as a protective amulet from evil
Term
Buttons are eaten off of the plants
Definition
Peyote
Term
Mescaline was isolated and synthesized
Definition
in 1918
Term
has been identified as primarily responsible for the visual effects in peyote
Definition
mescaline
Term
Users may experience bad trips as well as nausea and physical discomfort
Definition
mescaline
Term
More likely to cause ‘bad trips’ then other hallucinogenic
Definition
mescaline
Term
Mescaline High dose and low dose effects
Definition
Low dose effects are primarily euphoric
Higher doses cause the full set of hallucinogenic effects
Term
Entirely man made- completely synthetic
Definition
MDMA: “Ecstasy”
Term
MDMA is also called
Definition
Ecstasy
Term
Prior to the scheduling, some psychiatrists used this drug in practice because it was viewed as having a special ability to promote empathy, aiding in therapy
Definition
MDMA
Term
Increased tactile senses
Definition
MDMA
Term
Increased body temperature- to above 108*
Definition
MDMA
Term
Heightened sense of “closeness” with others
Definition
MDMA
Term
Involuntary jaw clenching and teeth grinding
Definition
MDMA
Term
MDMA selective destruction of
Definition
serotonin neurons
Term
Can completely deplete serotonin levels
Definition
MDMA
Term
Listed as a Schedule I drug but continues to be studied as a potential psychotherapeutic agent
Definition
MDMA
Term
PCP is what kind of drug
Definition
Hallucinogenic, Anesthetic (Pain Killer), Stimulant, Depressant
Term
Very different from other hallucinogens
Definition
PCP
Term
Deliriant drug
Definition
PCP
Term
Designed to be a large animal tranquillizer
Definition
PCP
Ketamine
Term
Other PCP-Like Drugs
Definition
ketamine, dextromethorphan, and nitrous oxide
Term
Users tend to try once and not like the effects and not use again
Definition
PCP
Term
Called “angel dust”
Definition
PCP
Term
Called “killer joints” or “sherms”
Definition
Joints made with PCP
Term
Marijuana is a
Definition
preparation of leafy material from the Cannabis plant that is smoked
Term
Effects include Sedation, Pain relief and Hallucinations (in large doses)
Definition
Marijuana
Term
Grown primarily for its fibers, from which hemp rope is made
Definition
Cannabis sativa
Term
A lanky plant up to 18 feet high
Definition
Cannabis sativa
Term
Cannabis: Three Species
Definition
Cannabis sativa
Cannabis indica
Cannabis ruderalis
Term
Grown for its psychoactive resins
Definition
Cannabis indica
Term
Higher THC than sativa
Definition
Cannabis indica
Term
A compact plant 2 to 3 feet high
Definition
Cannabis indica
Term
Potency varies depending on plant genetics and environmental conditions
Definition
Cannabis indica
Term
Grown primarily in Russia
Definition
Cannabis ruderalis
Term
THC is concentrated in the resin, most of which is in the
Definition
flowering tops of the plants
Term
THC is concentrated in the
Definition
resin of the plants
Term
Psychoactive potency of Cannabis preparations depends on
Definition
the amount of resin present
Term
Charas, also known as
Definition
hashish (resin)
Term
Ganja, also known as
Definition
sinsemilla
Term
Experienced grower only grows females
Definition
Ganja (sinsemilla)
Term
leaves or stems
Definition
Bhang
Term
Consists of pure resin that has been carefully removed from the surface of leaves and stems
Definition
Hashish
Term
Rare in the U.S.
Definition
Hashish
Term
Consists of dried flowering tops of plants with pistillate flowers (female plants)
Definition
Sinsemilla (Ganja)
Term
Male plants are removed from the fields before the female plants are pollinated
Definition
Sinsemilla (Ganja)
Term
Consists of the remainder of the Cannabis plant after the top has been picked
Definition
Bhang
Term
Typical range of potency is _____ percent THC
Definition
2-8%
Term
Law that taxed the marijuana grower, distributor, seller, and buyer
Definition
Marijuana Tax Act of 1937
Term
In what year did the U.S. Supreme Court declared the Marijuana Tax Act unconstitutional
Definition
1969
Term
Increased heart rate occurs after
Definition
smoking marijuana and ingesting oral THC
Term
Research findings on the effects of cannabinoids on blood pressure have
Definition
been mixed
Term
Marijuana connection to lung cancer
Definition
no connection
Term
Acute effects could be good for asthma
Definition
Bronchodilation effects of smoking marijuana
Term
Bronchodilation is seen following acute exposure to
Definition
marijuana
Term
Heavy marijuana smoking over a long period could lead to
Definition
clinically significant impairment of pulmonary function
Term
Reddening of the eyes
Definition
Effect of marijuana
Term
____ THC does not have high abuse potential, likely due to its different time course
Definition
Oral
Term
Effects include euphoria, “high,” mellowness, hunger, and stimulation
Definition
marijuana
Term
Marijuana's peak effects occur within _____ and last about
Definition
5-10 minutes
2 hours
Term
Acute administration of marijuana to infrequent users disrupts
Definition
cognitive performance
Term
Acute administration of marijuana to frequent users
Definition
Slowed cognitive processing consistently seen
Term
Clinical use of cannabis-based drugs for
Definition
appetite stimulation
Term
May relieve tension and migraine headaches
Definition
Marijuana
Term
May be effective as an anticonvulsant in some cases when preferred medication is ineffective
Definition
Marijuana
Term
Reduces fluid pressure in the eyes and may be useful in glaucoma patients
Definition
Marijuana
Term
Reduces severe nausea caused by certain drugs used to treat cancer
Definition
Marijuana
Term
Currently, ___ states have some form of legislation legalization of marijuana
Definition
14
Term
No listing of _____ withdrawal, BUT research suggests an abstinence syndrome does exist
Definition
cannabis
Term
Reduced testosterone levels in men
Definition
Marijuana
Term
Diminished sperm counts and abnormal sperm in men
Definition
Marijuana
Term
Amotivational syndrome
Definition
People that are high tend not to be motivated to be productive
Term
Some researchers are collecting data that they claim shows that marijuana causes psychosis
Definition
Marijuana Madness- 1935
Term
the single most important drug issue in the United States.
Definition
Marijuana
Term
Use reported in boxers, possibly to make them more aggressive and keep them from tiring quickly
Definition
Strychnine
Term
initially referred to a cheap brandy given to racing dogs and horses to slow them down
Definition
Doping
Term
Term came to refer to the opposite—an effort to improve rather than impair performance
Definition
Doping
Term
“energy producing,”
Definition
Ergogenic
Term
a general term for performance enhancement
Definition
Ergogenic
Term
Established medical use for weight gain in malnourished people
Definition
Steroids
Term
Drugs Used for Performance Enhancement
Definition
Stimulants
Steroids
Human growth hormone
Beta-2 agonists
Creatine
Term
Studies indicate that most athletes perform better on _________, but the improvement is small
Definition
amphetamines
Term
Androgenic effects (masculinizing) of natural testosterone
Definition
Growth of the penis and other male sex glands
Deepening of the voice
Increased facial hair
Term
Anabolic effects (tissue building) of natural testosterone
Definition
Increased muscle mass
Control of the distribution of body fat
Increased protein synthesis
Increased calcium in the bones
Term
“stacking”
Definition
Athletes may use combinations of steroids
Term
produce a stimulant-like high and increased aggressiveness
Definition
Steroids
Term
Peliosis hepatitis
Definition
Bloody liver cysts
Side effect of steroids
Term
Body acne
Definition
Side effect of steroids
Term
Baldness
Definition
Side effect of steroids
Term
Premature closure of the growth plates of the long bones, thus limiting adult height
Definition
Side effect of steroids
Term
male breast enlargement
Definition
Side effect of steroids
Term
Enlargement of the clitoris
Definition
Side effect of steroids
Term
Anabolic steroids are listed on Schedule
Definition
III
Term
A pituitary hormone that can potentially increase the height and weight of an individual to gigantic proportions
Definition
Human Growth Hormone
Term
Experiments have shown _____ may increase lean body mass but may not improve strength
Definition
Human Growth Hormone
Term
A natural substance found in meat and fish, sold legally as a dietary supplement
Definition
Creatine
Term
Helps regenerate ATP, which provides the energy for muscle contractions
Definition
Creatine
Term
extreme methods to achieve short-term weight loss
Definition
Purging
Diuretics
Sweating
Term
To attack the source of the drug problem
Definition
the demand for drugs must be eliminated
Term
Public health model:
Definition
primary, secondary, and tertiary prevention
Term
‘Treatment’
Definition
tertiary prevention
Term
Institute of Medicine’s “continuum of care”
Definition
Prevention
Treatment
Maintenance
Term
Universal prevention
Definition
entire population
Term
Selective prevention
Definition
high-risk groups within a population
Term
Indicated prevention
Definition
individuals who show signs of developing problems
Term
Knowledge-attitudes-behavior model
Definition
If you give people all the possible info about drugs then people wont use
Term
Affective education
Definition
Building self esteem
Talking about refusal skills
Term
Anti-drug norms
Definition
Talking about refusal skills
Term
Social influence model
Definition
Counter advertising
Where public commitments come into play
Talking about refusal skills
Term
DARE
Definition
Helpful in building relationships with local police
Proven not effective in preventing drug use
Term
ALERT: Based on
Definition
social influence model
Term
Life Skills Training: Based on
Definition
social influence model
Term
ALERT
Definition
Cigarette experimenters were more likely to quit or to maintain low rates of smoking
Initiation of marijuana smoking among nonusers was reduced
Level of marijuana smoking among users was reduced
Term
Life Skills Training
Definition
Teaches resistance skills, normative education, media influences, and general self-management and social skills
Term
of Americans undergo treatment for substance abuse and dependence each year
Definition
Hundreds of thousands
Term
Only acceptable treatment goal for alcohol dependence
Definition
complete abstinence
Term
View that substance dependence is a biological disease that someone either has or does not have
Definition
Alcohol Dependence
Term
A possible treatment goal is controlled social use
Definition
Alcohol Dependence
Term
Only acceptable treatment goal of Opioid dependence
Definition
is abstinence
Term
Most common goal of tobacco dependence
Definition
complete abstinence
Term
Disease Model of Alcohol Dependence
Definition
An alcoholic is biologically different from others, so abstinence is the only appropriate goal
Term
Uses the stages of change to get people through treatment
Definition
Alcoholics Anonymous
Term
Stages of change
Definition
Precontemplation
Contemplation
Preparation
Action
Maintenance
Term
Maintenance
Definition
Individual engages in activities intended to maintain the change
Term
Precontemplation
Definition
Individual doesn’t recognize that a problem exists
Term
Contemplation
Definition
Individual recognizes there is a problem and begins to consider the possibility of changing her or his behavior
Term
Preparation
Definition
Individual decides to change and makes plans to change
Term
Action
Definition
Individual takes active steps toward change
Term
Contingency Management
Definition
Given a reward for a clean screen
Term
An approach in which individuals receive immediate rewards for providing drug-free urine samples
Definition
Contingency Management
Term
An approach that combines cognitive therapy techniques with behavioral skills training
Definition
Cognitive Behavioral Therapy (CBT)
Term
Medications that are used to help block the effects or as a substitute for the drug
Definition
Pharmacotherapies
Term
a longer-term strategy used to help a dependent individual avoid relapse
Definition
Maintenance
Term
Three general categories of pharmacotherapy for maintenance
Definition
Agonist or substitution therapy
Antagonist therapy
Punishment therapy
Term
Agonist or substitution therapy
Definition
Nicotine replacement therapy
Methadone
Term
Antagonist therapy
Definition
Narcan- blocks effects of drug
Term
Punishment therapy
Definition
Exist mostly for alcohol
Antabuse- if given to person and they drink, they become violently ill
Term
an initial and immediate phase of treatment
Definition
Detoxification
Term
Most frequently reported drugs for substance abuse treatment admissions
Definition
Alcohol (40 percent)
Opioids (19 percent)
Marijuana/hashish (16 percent)
Cocaine (13 percent)
Stimulants (8 percent, primarily methamphetamine)
Term
Sites of treatment
Definition
47 percent treated as outpatients
13 percent treated as hospital inpatients (detoxification)
18 percent treated in a residential setting
Term
Naturally occurring substances derived from the opium poppy
Definition
Opioids
Term
have a 6,000-year history of medical use
Definition
Opioids
Term
Worldwide, opioids have been used to treat ______
Definition
diarrhea.
Term
Use of opioids for extended period of time causes
Definition
constipation
Term
________ has a opium addiction problem
Definition
Afghanistan
Term
Opium is produced and available for collection for
Definition
only a few days of the plant’s life
Term
The resinous substance that oozes from the cut in the opium poppy is
Definition
scraped and collected
Term
Raw opium is the substance from which _____ is extracted and then _______ is derived
Definition
morphine; heroin
Term
Morphine is _____ times as potent as opium
Definition
10
Term
Morphines is named after
Definition
Morpheus, the god of dreams
Term
Medically useful characteristics of morphine
Definition
Clinically useful
Pure chemical
Known potency
Term
__________ allowed delivery of morphine directly into the blood
Definition
Hypodermic syringe
Term
Year Hypodermic syringe was created
Definition
1853
Term
Widespread use during war provided relief from pain and dysentery
Definition
Morphine
Term
Many veterans were dependent on _________
Definition
Morphine
Term
“soldier’s disease” or “army disease”
Definition
Many veterans were dependent on Morphine
Term
Placed on the market in 1898 by Bayer
Definition
Heroine
Term
Heroine is ___ times as potent as morphine
Definition
3
Term
Acts like morphine except that it is more potent and acts more quickly
Definition
Heroine
Term
Originally marketed as a non-habit-forming substitute for codeine
Definition
Heroine
Term
Opium smoking increased after ____
Definition
1850, as Chinese laborers arrived in the U.S.
Term
Harrison and Opium Acts made it illegal to _____
Definition
smoke opium
Term
the most dangerous form of opioid use
Definition
Injection of morphine
Term
Number and proportion of Americans dependent on opioids peaked _______
Definition
at the start of the 20th century
Term
“vice of middle life”
Definition
Opioid dependence
Term
Typical user was a 30-50 year old middle class white woman, wife and mother
Definition
Opioids
Term
Initially, opioid dependence was viewed as a major social problem
Definition
not as a major social problem
Term
Oral use among white middle class ________ after the 1914 Harrison Act
Definition
declined
Term
After World War II, use of heroin increased in _______
Definition
low-income areas of large cities
Term
During the 1960s heroin use was associated with ____ and
Definition
crime and considered socially unacceptable
Term
Rate of Heroin use by American troops in Vietnam
Definition
5%
Term
Purity of heroine in Vietnam
Definition
About 95 percent pure (compared to 5 percent in the U.S.)
Term
Most soldier users _____ when they returned to the U.S.
Definition
stopped
Term
Opioid dependence and compulsive use are not inevitable among _________
Definition
occasional users
Term
The French Connection
Definition
in the early 1970s: heroin grown in Turkey, converted to heroin in southern France, and imported into the U.S.
Term
By 1975, most U.S. heroin came from ________
Definition
Mexico
Term
Mexican brown or black tar heroin
Definition
Opium processed into morphine, resulting in pure heroin with a brown or black color
Term
Heroin used in U.S. is currently produced mostly in
Definition
South America, Mexico, Southeast Asia and Afghanistan
Term
Purity of heroin from ________ is higher than heroin from ____
Definition
South America; Mexico
Term
Recent deaths of celebrities, like Michael Jackson and Heath Ledger has reignited concerns about
Definition
Physicians over prescribing opioid pain medications
Term
Raw opium is about
Definition
10 percent morphine by weight, and a smaller amount of codeine
Term
Natural Prescription Narcotic Analgesics
Definition
Morphine
Codeine
Term
Semisynthetic Prescription Narcotic Analgesics
Definition
Heroin
Diamorph (unavailable in U.S.)
Term
Synthetic Prescription Narcotic Analgesics
Definition
Methadone
Meperidine
Oxycodone
Oxymorphone
Hydrocodone
Hydromorphone
Dihydrocodeine
Propoxyphene
Pentazocine
Fentanyl
Term
Drugs that block the action of opioids
Definition
Opioid antagonists
Term
Examples of Opioid antagonists
Definition
Naloxone (Narcan) and nalorphine
Term
Effects of Opioid antagonists
Definition
Reverse depressed respiration from opioid overdose
Precipitate withdrawal syndrome
Prevent dependent individuals from experiencing a high from subsequent opioid use
Term
Medical Uses of Opioids
Definition
Pain relief
Treatment of intestinal disorders
Cough suppressant
Term
Vietnam soldier drug use experience showed
Definition
Under certain conditions, a relatively high percent of individuals will use
Term
Opioid Tolerance develops from
Definition
effects from both medical and recreational usage
Term
Cross-tolerance exists among all the
Definition
opioids
Term
Psychological processes play a key role in ______ tolerance
Definition
opioid
Term
Symptoms of ________ withdrawal appear in sequence following the timing of the most recent dose and the individual’s history of use
Definition
opioid
Term
Opioid withdrawal is
Definition
unpleasant but rarely life-threatening
Term
____ produces opioid withdrawal symptoms that appear later and are less severe than those from heroin
Definition
Methadone
Term
Positive reinforcement
Definition
Positive effects reliably follow use of the drug
Term
Negative reinforcement
Definition
Use of the drug removes withdrawal symptoms
Term
___________ opioids are most likely to lead to dependence
Definition
Fast-acting injectable
Term
Opioid overdose triad
Definition
Coma
Depressed respiration
Pinpoint pupils
Term
Infections and the spread of blood-borne diseases
Definition
associated with injection method of drug use
Term
Number of heroine injections needed daily to prevent withdrawal
Definition
3 to 4
Term
Health problems associated with injection habit
Definition
Skin infections
Blood-borne infections
Masking of early symptoms of illness
Term
Opioid tolerance to _____ effects may develop more rapidly than tolerance to ______ effects
Definition
negative; positive
Term
_____ Withdrawal is often similar to a mild case of the intestinal flu
Definition
opioid
Term
heroin chippers
Definition
occasional users
Term
Number of opioid-dependent Americans
Definition
1 million
Term
Craving for drugs, anxiety
(Approximate hours after previous dose)
Definition
Heroin or Morphine- 6
Methadone- 24
Term
Yawning, perspiration, running nose, teary eyes
(Approximate hours after previous dose)
Definition
Heroin or Morphine- 14
Methadone- 34-48
Term
Increase in above signs plus pupil dilation, goose bumps, tremors, hot and cold flashes, aching bones and muscles, loss of appetite
(Approximate hours after previous dose)
Definition
Heroin or Morphine- 16
Methadone- 48-72
Term
plus insomnia; raised blood pressure; increased temperature, pulse rate, respiratory rate and depth; restlessness; nausea
(Approximate hours after previous dose
Definition
Heroin or Morphine- 24-36
Methadone- never
Term
plus curled-up position, vomiting, diarrhea, weight loss, spontaneous ejaculation or orgasm, hemoconcentration, increased blood sugar
(Approximate hours after previous dose)
Definition
Heroin or Morphine- 36-48
Methadone- never
Term
In 1926 series of newspaper articles linked _____ and crime
Definition
marijuana
Term
“pyramid of prejudice” against marijuana
Definition
Marijuana use associated with lower-class groups and recent immigrants
Regular references made in popular literature to the murdering cult of assassins as suggestive of the characteristics of the drug
Term
Within ____ minutes, most THC is gone from the brain
Definition
30
Term
Dryness of the mouth and throat
Definition
Effect of smoking mariuana
Term
No human overdose deaths have been reported for what drug
Definition
Marijuana
Term
Marijuana smoke contains many, but not all of
Definition
of the same chemicals found in tobacco smoke
Term
Some evidence that ____ use reduces immunity to infection
Definition
marijuana
Term
Seniors who smoked marijuana peaked in the _____
Definition
1970s.
Term
____deliver pleasure and relief from anxiety
Definition
Opioids
Term
Reduces the emotional response to pain and diminishes the patient’s awareness of, and response to, the aversive stimulus
Definition
Opioids
Term
reduce coughing
Definition
Opioids
Term
________ depress respiratory centers in the brain
Definition
Opioids
Term
Opioid overdose triad
Definition
Coma
Depressed respiration
Pinpoint pupils
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