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Uptake and Distribution of Anesthetics
Pharmacology
7
Medical
Professional
01/16/2012

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Cards

Term
what is the maximum effect of a given dose?
Definition
the time required to reach max partial pressure in target tissue for administered dose
Term
what does the rate of rise fo the alveolar concentration depend on?
Definition
Inspired concentration
Alveolar or minute ventilation
FRC
Term
what is the relationship b/t FRC and inhaled drug?
Definition
Low FRC = faster induction of anesthesia
Term
what are the 3 factors that uptake into the blood depends on?
Definition
Solubility
Cardiac Output
Alveolar to venous conc gradient
Term
In terms of solubility, rank drugs from greatest to least
Definition
halothane, isoflurane, N2O, Desflurane, Sevoflurane
Term
What is the relationship b/t CO and drug induction?
Definition
Incr in CO slows drug induction and peak time effect
Term
what is the relationship between induction time and A-V conc?
Definition
incr. A-V conc. increases induction time, therefore increasing the time to peak maximal effect
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