Term
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Definition
| controls intestinal motility |
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Term
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Definition
| controls intestinal motility |
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Term
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Definition
| appetite suppressant; sympathomimetic - increases catecholamines; can be habit forming and has side effects and interactions w/ other drugs |
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Term
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Definition
| aid to digestion; pancreatic supplement for pancreatic insufficiency (may be from pork); taken before meals |
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Term
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Definition
| aid to digestion; tri-keto bile salt that increases bile flow - forms micelles and increases osmotic pressure of bile |
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Term
| Medium chain triglycerides |
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Definition
| aid to digestion; do not require bile salt micelles to go into solution |
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Term
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Definition
| for gallstones; suppresses hepatic cholesterol synthesis |
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Term
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Definition
| for gallstones; shifts bile acid:phospholipid:cholesterol phase diagram to liquid crystal zone |
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Term
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Definition
| for retained duct gall stones |
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Term
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Definition
| for retained duct gall stones |
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Term
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Definition
| for retained duct gall stones |
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Term
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Definition
| given together for gallstones after treatment with lithotripsy (ultrasound) |
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Term
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Definition
| can cause gastric and duodenal ulcers b/c they are COX-1 inhibitors which decrease prostaglandins which cause mucus secretion |
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Term
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Definition
| can cause gastric and duodenal ulcers b/c they are COX-1 inhibitors which decrease prostaglandins which cause mucus secretion |
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Term
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Definition
| good alternative for pt. w/ gastric or duodenal ulcers |
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Term
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Definition
| good alternative for pt. w/ gastric or duodenal ulcers (b/c a COX-2 inhibitor) |
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Term
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Definition
| treatment of excess acid; antacid |
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Term
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Definition
| treatment of excess acid; antacid |
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Term
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Definition
| treatment of excess acid; antacid |
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Term
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Definition
| treatment of excess acid; H-2 receptor antagonist |
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Term
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Definition
| treatment of excess acid; mucosal protecting agents; binds covalently to an ulcer, producing a shield, must be activated by acid |
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Term
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Definition
| treatment of excess acid; H+,K+ATPase inhibitor; a PRO-DRUG (R and S enantiomers) - absorbed in the inactive R form and converted by the acid from the parietal cell to the S form; then binds to the H+/K+ATPase and inactivates it; used to treat Zollinger-Ellison syndrome (ZE syndrome) |
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Term
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Definition
| treatment of excess acid; eradication of h. pylori |
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Term
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Definition
| antacid; rapid effect, absorbed |
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Term
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Definition
| antacid; rapid neutralization, some absorbed, night time acid rebound |
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Term
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Definition
| antacid; neutralizes acid, low absorption can cause diarrhea |
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Term
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Definition
| antacid; slower acid neutralization, low absorption, can complex certain drugs, causes constipation |
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Term
| Sucralfate (aluminum sucrose sulfate) |
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Definition
| mucosal protecting agent; binds covalently to ulcer, producing a shield, requires acid to be activated |
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Term
| Carbenoxolone (derivative of glycyrrhizinic acid) |
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Definition
| mucosal protecting agent; alters mucus production, has aldosterone-like side effect |
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Term
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Definition
| mucosal protecting agent; a PGE1 analog (prostaglandin), lowers c-AMP in parietal cells, many side effects, induces labor |
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Term
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Definition
| H2-receptor antagonist; prevents elevation of parietal cell c-AMP mediated by the H2 receptor |
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Term
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Definition
| H2-receptor antagonist; prevents elevation of parietal cell c-AMP mediated by the H2 receptor; much more potent than cimetidine; low side effects |
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Term
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Definition
| H2-receptor antagonist; prevents elevation of parietal cell c-AMP mediated by the H2 receptor |
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Term
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Definition
| H2-receptor antagonist; prevents elevation of parietal cell c-AMP mediated by the H2 receptor |
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Term
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Definition
| M-receptor antagonist; prevents Ca2+ entry into cells |
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Term
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Definition
| treatment of H. pylori associated ulcer disease (an antibiotic) |
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Term
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Definition
| treatment of H. pylori associated ulcer disease (an antibiotic) |
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Term
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Definition
| treatment of H. pylori associated ulcer disease (an antibiotic) |
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Term
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Definition
| alcoholic drinks, appetizers (spicy hors d'oeuvres), alkaloids (vagal stimulation), thyroid hormone, insulin |
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Term
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Definition
Muscarinic (M1 and M3) - G-protein coupled Ach receptor that activates phospholipase C to make inositol phosphates and intracellular Ca
- Nicotinic - Ach receptor that uses an ion channel mechanism |
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Term
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Definition
- Adrenoreceptors - G-protein coupled receptor that responds to the catecholamines adrenaline and noradrenaline
- also to alpha-phenylephrine, beta-isoprenaline, and dopamine |
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Term
| Serotonin 5-HT3 receptors |
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Definition
- member of the Cys-loop superfamily of ligand-gated ion channels; not a G-protein coupled receptor
- METOCLOPRAMIDE is a weak serotonin antagonist |
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