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Unit 9 neuro
The Central Visual System: Processing Information and The Control of Movement
172
Physiology
Undergraduate 3
10/28/2014

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Term
T/F Vision is the dominant sense to adapt to change in the environment.
Definition
true
Term
where does all sensory input go to?
Definition
the thalamus
Term
what are the levels of processing for the visual sense?
Definition
eyes->
thalamus->
primary visual cortex
Term
what is phototransduction?
Definition
convert light energy into action potentials
Term
what is parallel processing?
Definition
information is processed at multiple locations at the same time
Term
give an example of parallel processing.
Definition
the brain divides what it sees into color, motion, shape, and depth.
These components are individually analyzed and then compared to stored memories
Term
what is hierarchal processing?
Definition
information is processed first at one level then output to another higher level
Term
give an example of hierarchal processing.
Definition
objects can be viewed as a collection of lines, then shapes, then into objects
Term
explain conscious visual perception.
Definition
active focus on the visual stimuli to interpret what was seen
Term
where is visual information from the retina relayed to?
Definition
the lateral geniculate nucleus of the thalamus to the primary visual cortex
Term
where is the lateral geniculate nucleus located?
Definition
occipital lobe
Term
what is the central visual system (CVS)?
Definition
a pathway in which information from out visual field is processed
Term
what is a binocular visual field?
Definition
the sum of both eyes is interpreted as one picture
Term
T/F visual stimuli from each eye only projects to one side of the brain.
Definition
false
each eye projects to each side of the brain
Term
what are the three components of the retina?
Definition
retina
interneurons
ganglion cell
Term
name the ten layers of the retina.
Definition
1-Pigment Epithelium
2-Rod and Cone Layer
3-External Membrane
4-Outer Nuclear Layer
5-Outer Plexiform Layer
6-Inner Nuclear Layer
7-Inner Plexiform Layer
8-Ganglion Cell Layer
9-Optic Nerve Fiber Layer
10-Internal Limiting Membrane
Term
what are the three types of interneuron?
Definition
bipolar cells
amacrine cells
horizontal cells
Term
what is the function of the interneurons?
Definition
further sort visual information
Term
what is the pigment epithelium?
Definition
deepest layer
absorbs excess light
Term
what is the rod and cone layer?
Definition
photoreceptor cells
Term
what is the external membrane?
Definition
intercellular junction binding Mueller cells
Term
what is the outer nuclear layer?
Definition
cell bodies of rods and cones
Term
what is the outer plexiform layer?
Definition
synaptic area with terminals of rods and cones and horizontal and bipolar cells
Term
what is the inner nuclear layer?
Definition
cell bodies of interneurons
Term
what is the inner plexiform layer?
Definition
synaptic area of terminals of interneurons and ganglion cells
Term
what is the ganglion cell layer?
Definition
cell bodies of ganglion cells
Term
what is the optic nerve fiber layer?
Definition
axons of ganglion cells form thick bundles of the optic nerve which terminates in the lateral geniculate nucleus of the thalamus
Term
what is the internal limiting membrane?
Definition
membrane made of basal lamina between vitreous body and Mueller cells
Term
what is a general description of the retina?
Definition
thin layer of cells at the back of the eyeball which converts light into nervous signals
Term
T/F the retina detects light but also plays an important role in visual perception.
Definition
true
Term
explain the rods.
how many?
what do they detect?
where are they located?
Definition
100-120 million
stimulated by low levels of light
located at the periphery
Term
explain the cones.
how many?
what do they detect?
where are they located?
Definition
6-7 million
stimulated by high intensity light and mediate sharp vision and color
centrally located
Term
T/F cones detect shades and dark.
Definition
false
rods
Term
T/F cones detect light and detail.
Definition
true
Term
T/F interpretation of visual stimulus does not require conscious thought.
Definition
false, it does
Term
what is the outer segment of rods and cones?
what is it?
Definition
dendritic end
photosensitive-modified cilium
Term
the inner segment of the rods and cones house what?
Definition
the nucleus
Term
explain the discs in the rods and cones.
Definition
rods: discs form within the cytoplasm

cones: discs are infoldings of the outer segment
Term
what is a general description of the retina?
Definition
thin layer of cells at the back of the eyeball which converts light into nervous signals
Term
T/F the retina detects light but also plays an important role in visual perception.
Definition
true
Term
explain the rods.
how many?
what do they detect?
where are they located?
Definition
100-120 million
stimulated by low levels of light
located at the periphery
Term
explain the cones.
how many?
what do they detect?
where are they located?
Definition
6-7 million
stimulated by high intensity light and mediate sharp vision and color
centrally located
Term
T/F cones detect shades and dark.
Definition
false
rods
Term
T/F cones detect light and detail.
Definition
true
Term
T/F interpretation of visual stimulus does not require conscious thought.
Definition
false, it does
Term
what is the outer segment of rods and cones?
what is it?
Definition
dendritic end
photosensitive-modified cilium
Term
the inner segment of the rods and cones house what?
Definition
the nucleus
Term
explain the discs in the rods and cones.
Definition
rods: discs form within the cytoplasm

cones: discs are infoldings of the outer segment
Term
what is the pigment of rods?
Definition
rhodopsin
Term
what is the pigment of cones?
Definition
iodopsin
Term
what triggers the rods and cones?
Definition
light energy
Term
where does phototransduction being and end?
Definition
begins: rhodopsin in the disk membrane

ends: in plasma membrane hyperpolarization
Term
what happens when light strikes a photoreceptor?
Definition
it it initiates a process that reduces the release of glutamate
Term
what does glutamate affect in visual processing in the retina?
Definition
the activity of bipolar and horizontal cells
Term
what do bipolar cells synapse with in visual processing in the retina?
Definition
amacrine and retinal ganglion cells
Term
the transduction of visual information from the eye to the brain uses what types of cells?
Definition
bipolar and ganglion cells
Term
what is the role of horizontal cells in the visual processing in the retina?
Definition
modulate the synaptic activity of receptor cells
Term
what is the role of amacrine cells in the visual processing in the retina?
Definition
modulate synaptic activity of the retinal bipolar and ganglion cells
Term
what happens when cGMP concentration decreases?
Definition
depolarization decreases
Term
what happens to cGMP concentrations in dark conditions?
Definition
increase
depolarize
Term
what happens to cGMP concentrations in light conditions?
Definition
decrease
hyperpolarize
Term
what receptors are embedded in the disc membrane?
Definition
G-protein couples receptors
Term
what is important to note about G-protein coupled receptors?
Definition
they have second messengers
Term
the combination of rhodopsin and vitamin a make what?
Definition
metarhodopsin 2
Term
what are the steps of phototransduction?
Definition
1-light is absorbed by rhodopsin->makes metarhdopsin->activates transducin
2-transducin binds to GTP
3-the alpha subunit-GTP complex activates phosphodiesterase
4-phosphodiesterase breaks down cGMP to 5'-GMP (decreases cGMP concentration)
5-sodium channels close causing hyperpolarization
6-hyperpolarization causes VGCC to close reducing glutamate concentration
7-decreased glutamate causes depolarization of ON center bipolar cells and hyper polarization of OFF center bipolar cells
Term
how is transducer made?
Definition
light is absorbed by rhodopsin, with combination of vitamin a metarhodopsin is made and then transducin
Term
how is metarhodopsin 2 made?
Definition
rhodopsin and vitamin a
Term
what converts cGMP to 5'-GMP?
Definition
phosphodiesterase
Term
what gates close when the concentration cGMP decreases?
Definition
ionic K, Na, and Ca2+
Term
what happens when metarhodopsin 2 hits the GProtein?
Definition
the alpha subunit triggers phosphodiesterase
Term
what is the key molecule of phototransduction?
Definition
cGMP
Term
what depolarizes OFF bipolar cells?
Definition
glutamate
Term
what hyper polarizes ON cells?
Definition
glutamate
Term
what do OFF cells do?
Definition
detect dark objects in a lighter background
Term
what do ON cells do?
Definition
detect objects in a dark background
Term
what are the two modes of action of glutamate?
Definition
depolarize OFF bipolar cells and hyper polarizes ON bipolar cells
Term
depolarization of horizontal cells causes the release of what?
Definition
GABA
Term
what cells depolarize by the release of glutamate in no light conditions?
what happens in light conditions?
Definition
horizontal cells

horizontal cells are not depolarized
Term
explain the statement: Bipolar cells have concentric receptive fields"
Definition
Light directed on a photoreceptor that synapse with a bipolar cell produces a center response. Whereas light directed on immediately surrounding receptors produce the opposite response.
Term
cone-bipolar cell is color sensitive/insensitive.
Definition
sensitive
Term
rod-bipolar cell is color sensitive/insensitive.
Definition
insensitive
Term
OFF triggers depolarization/hyperpolarization.
Definition
depolarization
Term
ON triggers depolarization/hyperpolarization.
Definition
hyperpolarization
Term
T/F bipolar cells synapse on multiple rods and cones.
Definition
true
Term
explain why ganglion cells are the final output neurons.
Definition
collect visual information from the interneurons and transmit it to the brain
Term
T/F amacrine cells are the second synaptic retinal layer.
Definition
true
Term
which direction do amacrine cells shift information?
how?
Definition
laterally

through extensive dendritic trees
Term
P ganglion cells make synaptic contact with ____bipolar cells.
Definition
cone
Term
characterize P ganglion cells.
Definition
color sensitive
small concentric receptive field
produces a slow adaptive response
produces weak responses to stimuli
Term
T/F rods-> interneuron layers-> ganglion cells-> P ganglion cells
Definition
false
cones
Term
M retinal ganglion cells synapse with ____ bipolar cells.
Definition
rod
Term
characterize M rential ganglion cells.
Definition
color insensitive
large concentric receptive field
sensitive to small center-surround brightness differences
produces rapid adaptive response
detects motion in the periphery
Term
T/F M retinal ganglion cells are larger than P ganglion cells.
Definition
true
Term
what makes up the optic nerve?
Definition
retinal ganglion cell axons and support cells
Term
where do most of the axons of the optic nerve terminate?
Definition
lateral geniculate nucleus
Term
what is the optic chiasm?
Definition
part of the brain where the optic nerves partially cross over
Term
what is the optic tract?
Definition
continuation of the optic nerve from the optic chiasm to the lateral geniculate nucleus
Term
what is Meyer's Loop?
Definition
loop into the temporal lobe (memory) to get to the visual cortex
Term
what would happen if there was damage to the temporal lobe, what could happen to vision?
Definition
possible to lose vision in the part of the eye that deals with that quadrant (superior quadrant)
Term
what is the pathway of optic radiation?
Definition
photoreceptors->
bipolar cells->
ganglion cell bodies->
optic nerve->
quadrants->
cross at chiasm->
LGN->
fan out at Meyer's Loop->
visual cortex
Term
what is the purpose of Meyer's Loop?
Definition
feed visual information to a memory structure
Term
visual information goes to what memory structures in the brain?
Definition
temporal
Term
what does the parietal lobe deal with?
Definition
spatial representation
Term
what is another name for optic radiation?
Definition
geniculo-calcerine tract
Term
explain association cortex.
Definition
3 areas shape visual information
occipital
temporal
parietal
Term
what is the total visual field?
Definition
entire are that can be seen with both eyes
Term
T/F visual information is shared across both hemispheres
Definition
true
Term
where does the retina project mainly?
what two other structures?
Definition
lateral geniculate nucleus
superior colliculus

hypothalamus
pretectum
Term
where does the LGN relay information?
Definition
primary visual cortex
Term
what is the superior colliculus in charge of?
Definition
reflexive eye movements
Term
what does the pretectum control?
Definition
pupil size
Term
T/F 10-20% of visual information goes to the LGN.
Definition
false
80-90% to the LGN
10-20% to the SC
Term
explain the pathway of optic projection.
Definition
Retina->
LGN->
VI+ (PVC)->
the projects forward
Term
the multiple sites of visual processing is an example of
Definition
parallel processing
Term
the thalamus is synonymous to
Definition
I-95
Term
the thalamus is responsible for what?
Definition
initial processing of all sensory information except olfaction
Term
what is the lateral part of the thalamus responsible for?
Definition
integration of sensory information and sends nerve impulses to the parietal, temporal and occipital lobes for further processing
Term
how many layers are there in the LGN? why?
Definition
6
because there are 6 layers of the visual cortex
Term
what is the LGN?
Definition
primary relay center for visual information from the retina
Term
where does the LGN come into play in optic radiation?
Definition
rods and cones project to the->
LGN projects to the cortex
Term
if visual information comes in at the right side of the eye what hemisphere does it project to?
Definition
right
Term
what are the cell types of the LGN?
Definition
M cells
P cells
K cells
Term
what is the source of information for M cells?
Definition
rods
Term
what is the source of information for P cells?
Definition
cones
Term
what is the point of splitting information from each side of the brain?
Definition
the angle at which light enters each eye is different at different angles
Term
where is the SC located?
Definition
in the midbrain posterior to the thalamus
Term
T/F the SC is part of the thalamus.
Definition
false
Term
where does sensory input to the SC come from?
Definition
vestibular apparatus
retina
PVC
Term
what is the tectospinal tract?
Definition
projection to the level of the spinal cord
Term
no matter the source of input to the SC what track is taken?
Definition
SC->
brain stem->
AMN->
muscles of the head and neck
Term
give an example of the SC and reflexive control of the head and neck.
Definition
flash of light to your left causes you to turn your head to the left
1)retina projects to the superficial layers of the right SC
2)superficial layers to the intermediate and deep layers
3)long crossed tectospinal axons to the left side of the cervical spinal cord
4)spinal cord neurons on the left side innervate head and neck muscles
5)turn your head to the left
Term
T/F specific areas of the SC handle specific information
Definition
true
Term
what does the topographical map the SC creates represent?
Definition
represents visual space around us with input from auditory and somatosensory sources
creating spacial awareness
Term
what is fixation?
Definition
the eyes are directed toward a motionless object, with eye movements to compensate for movements of the head
Term
what is smooth pursuit?
Definition
the eyes move steadily to track a moving object
Term
what is saccades?
Definition
the eyes move rapidly from one location to another (jumps)
Term
what is vergence?
Definition
the eyes move simultaneously in opposite directions to obtain or maintain single binocular vision
Term
T/F there are six layers in the PVC just like the LGN.
Definition
true
Term
what are the layers that have reasonable information.
Definition
V1, V2, V3 and V5
Term
V1 receives input from where?
Definition
LGN
Term
V1 is also known as what?
Definition
primary visual cortex
Term
V1 transmits information on what two pathways?
Definition
ventral stream
dorsal stream
Term
M type cells project to what lobes
Definition
medial temporal lobe
then to parietal lobe
Term
the P cells project where?
Definition
to V4 then into the temporal lobe
Term
blobs are
Definition
p type cells
Term
inter blobs are
Definition
m type cells
Term
what type of cells detect movement?
Definition
m type
Term
what type of cells detect shapes?
Definition
p type
Term
the ventral stream is associated with what?
Definition
form recognition and object representation and color
storage of long term memory
Term
the ventral stream is associated with what types of cells?
Definition
P cells
Term
what is another name for the ventral stream?
Definition
What Pathway
Term
the dorsal stream is associated with what?
Definition
motion
representation of objects locations
control of eyes and arms
Term
the dorsal stream is associated with what types of cells?
Definition
M cells
Term
what is another name for the dorsal stream?
Definition
Where or How Pathway
Term
what did a study of reaction time in baseball players find?
Definition
better hitters had better reaction times
Term
what does time to contact equal?
Definition
size of the retinal image divided by the rate of change in size of the image
Term
what did whiting find in his vision and catching study?
Definition
the longer people had to look at the ball before the light turned off the more catches were made
Term
what are the three ways the PVC elaborates the elemental information from the cells?
Definition
1)each part of the visual field is decomposed into short line segments through orientation columns
2)color processing occurs in cells that lack orientation selectivity in regions called blobs
3)the input from the two eyes is combined through the ocular dominance columns, necessary for depth perception
Term
the ganglion cells projects to the LGN in a way that creates what?
Definition
a complete retinotopic map of the visual field for each eye
Term
T/F the M and P cells of the retina project to the same areas of the LGN
Definition
false
to different layers
Term
where does each geniculate axon terminate mainly?
Definition
V4
Term
neurons with similar response properties in different vertically oriented systems are linked by what connections?
Definition
horizontal connections
Term
what does the SC control?
Definition
reflexive eye movement
Term
T/F the SC is part of the thalamus.
Definition
false it is nonthalamic
Term
where do most of the projects to the SC come from?
Definition
rods
Term
where does the SC project information to?
and further?
Definition
the brain stem
to the cervical spinal cord to innervate AMN to innervate muscles in the head and neck
Term
the SC receives input from the retina but also where else?
Definition
proprioceptive
auditory
Term
Explain the notion that the SC creates a topographic map.
what does this give us?
Definition
receives stimulus from rod and cones to create a 2D map of the visual field, which can be divided into upper and lover quadrants.

subconscious recognition in space
Term
some retinal projects bypass the LGN and go where?
Definition
SC
Term
what level of the visual cortex does most visual input go to?
Definition
V4
Term
explain the pathway to the visual cortex.
Definition
light->
retina->
6 layers of the LGN->
6 layers of the visual cortex
Term
what direction does the levels of the visual cortex share information?
Definition
horizontally
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