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Unit 4
Antiinfectives, Chemo, Mobility, Periop
84
Nursing
Undergraduate 2
04/06/2021

Additional Nursing Flashcards

 


 

Cards

Term
Bacteriostatic 
Definition

 

does not kill organisms but rather prevents reproduction of organisms

Term
Red Man's Syndrome
Definition

Hypotension and skin flushing from infusing Vancomycin too fast

resolves when infusion rate slowed down

Term
Penicillins
Definition
High rate of sensitivity reactions ranging from rashes to anaphylaxis
Term
Tetracyclines
Definition
Require sun protection ie hat, sunscreen, long pants, long sleeves
Term
Sulfa Drugs
Definition
Associated with hypersensitivities and serious skin reactions
Term
Metronidazole
Definition
Used to sterilize the gut, eradicate intestinal infections and treats bacterial and protozoal vaginal infections 
Term
Cephalosporins
Definition
Antabuse effect with alcohol consumption
Term
Macrolides
Definition
High association with development of C. difficile
Term
Fluoroquinolones (-floxacin)
Definition
Associated with rupture of the Achilles tendon and neuropathy
Term
Tetracyclines
Definition
Inactivation of Hormonal Birth Control Methods. Must use barrier methods for 3 months
Term
Sensitivity Report
Definition
A report that indicates which anti-infectives are most effective in eliminating a specific infectious organism 
Term
Cross Sensitivity
Definition

A sensitivity reaction to a drug because the patient is sensitive to another drug

Ex: Penicillin and Cephalosporins 

Term
Peak
Definition

The highest serum level of a drug

Draw 30-60 minutes after dose administered

Term
Trough
Definition

The lowest serum level of a drug

Draw just before dose administration

Term
Aminoglycosides (-MYCINS)
Definition

Very potent

Require peak/trough and creatinine monitoring

Toxic to kidneys, ears

Term
Macrolide (-THROMYCIN)
Definition
Used when hypersensitivity to penicillin exists
Term
Bactericidal 
Definition

(-cidal means kill)

Works by destroying bacterial organisms

Term
Metronidazole
Definition
Causes serious Antabuse-like reaction when alcohol is consumed
Term
Vancomycin
Definition
Glycopeptide that acts like aminoglycoside
Term
Tetracyclines
Definition

Contraindicated in pregnant women and children under 8 years

Bone and tooth damage

Term
Cephalosporins
Definition

Derived from penicillin

Come in different generations

Patients with penicillin allergy may react the same with cephalosporins

Term
Phenazopyridine
Definition
A urinary tract anesthetic used to treat the symptoms of UTI.  Turns urine dark orange. Does not eradicate bacteria
Term
Fluconozole (-conozole)
Definition
An antifungal used to prevent/treat yeast infections that occur from antibiotic therapy
Term
Antivirals (-cyclovir) Acyclovir, Valacyclovir
Definition
A group of antiviral medications used most often to treat herpesvirus
Term
Vesicant
Definition

A drug that causes significant tissue damage when extravasated

 

Term

Extravasation

 

Definition
When a vesicant drug leaks out of the vascular space into the surrounding tissue
Term
Vinca Alkaloids
Definition

Chemotherapy drugs manufactured from the Vinca plant

 

Toxicity: Neurologic Fxn - hearing, constipation

Term

VinCRISTINE

VinBLASTINE

Definition
Vinca Alkaloids
Term

Doxorubicin

Adriamycin

 

The "RED DEVIL"

Definition

An antitumor antibiotic

Strong Vesicant

Turns urine red, total alopecia

Very damaging to tissues if extravasates 

[image]

Term

Cyclophosphamide

 

Definition

A chemotherapy that is often used to treat cancers as well as an immunosuppressant in autoimmune diseases

 

May cause hemorrhagic cystitis (bladder bleeds)

Must keep well hydrated

Term

5-fluoracil

5-FU

Definition

Chemotherapy used most often for GI/Biliary cancers

May cause severe stomatitis

[image]

Term
Methotrexate
Definition

A chemotherapy drug used to treat cancer, autoimmune disease (immunosuppressant) and ectopic (tubal) pregnancy

 

If given in high doses, patients must receive a rescue agent to block the effects after a certain time period

Term
Leucovorin Calcium
Definition

The rescue agent used when high-dose methotrexate is given.  MUST be given ON TIME.

 

Prolonged exposure to methotrexate can cause death

Term
Ifosfamide
Definition

An alkylating agent chemotherapy used for cancer treatment

May cause hemorrhagic cystitis

 

Must be treated with a rescue agent if given in high doses

 

Term
Superinfection
Definition
A secondary infection occurring after treatment for a primary infection Ex. yeast infections or C. diff after use of broad spectrum antibiotics
Term
Monoamine Oxidase Inhibitor
Definition
A class of drugs that when used in Parkinson's Disease inhibits the breakdown of dopamine in the brain
Term
Dopaminergic
Definition
A drug used to mimic the effects of dopamine or that is converted to Dopamine in Parkinson's Disease
Term
Dopamine Agonist
Definition
A class of drugs used to make dopamine receptors more sensitive to Dopamine - these drugs enhance the effects of Dopamine
Term
Anticholinergics
Definition
A class of drugs that inhibit the effects of acetylcholine.  Used in Parkinson's Disease to decrease muscle tremors and rigidity and to decrease drooling. 
Term
Levodopa
Definition
A dopaminergic that converts to dopamine in the brain.  Reduces the symptoms of Parkinson's Disease
Term
Seligiline
Definition
monoamine oxidase inhibitor
Term
Carbidopa
Definition
Used with levadopa as a dopamine agonist
Term
Bacteriostatic 
Definition

 

does not kill organisms but rather prevents reproduction of organisms

Term
Red Man's Syndrome
Definition

Hypotension and skin flushing from infusing Vancomycin too fast

resolves when infusion rate slowed down

Term
Penicillins
Definition
High rate of sensitivity reactions ranging from rashes to anaphylaxis
Term
Tetracyclines
Definition
Require sun protection ie hat, sunscreen, long pants, long sleeves
Term
Sulfa Drugs
Definition
Associated with hypersensitivities and serious skin reactions
Term
Metronidazole
Definition
Used to sterilize the gut, eradicate intestinal infections and treats bacterial and protozoal vaginal infections 
Term
Cephalosporins
Definition
Antabuse effect with alcohol consumption
Term
Macrolides
Definition
High association with development of C. difficile
Term
Fluoroquinolones (-floxacin)
Definition
Associated with rupture of the Achilles tendon and neuropathy
Term
Tetracyclines
Definition
Inactivation of Hormonal Birth Control Methods. Must use barrier methods for 3 months
Term
Sensitivity Report
Definition
A report that indicates which anti-infectives are most effective in eliminating a specific infectious organism 
Term
Cross Sensitivity
Definition

A sensitivity reaction to a drug because the patient is sensitive to another drug

Ex: Penicillin and Cephalosporins 

Term
Peak
Definition

The highest serum level of a drug

Draw 30-60 minutes after dose administered

Term
Trough
Definition

The lowest serum level of a drug

Draw just before dose administration

Term
Aminoglycosides (-MYCINS)
Definition

Very potent

Require peak/trough and creatinine monitoring

Toxic to kidneys, ears

Term
Macrolide (-THROMYCIN)
Definition
Used when hypersensitivity to penicillin exists
Term
Bactericidal 
Definition

(-cidal means kill)

Works by destroying bacterial organisms

Term
Metronidazole
Definition
Causes serious Antabuse-like reaction when alcohol is consumed
Term
Vancomycin
Definition
Glycopeptide that acts like aminoglycoside
Term
Tetracyclines
Definition

Contraindicated in pregnant women and children under 8 years

Bone and tooth damage

Term
Cephalosporins
Definition

Derived from penicillin

Come in different generations

Patients with penicillin allergy may react the same with cephalosporins

Term
Phenazopyridine
Definition
A urinary tract anesthetic used to treat the symptoms of UTI.  Turns urine dark orange. Does not eradicate bacteria
Term
Fluconozole (-conozole)
Definition
An antifungal used to prevent/treat yeast infections that occur from antibiotic therapy
Term
Antivirals (-cyclovir) Acyclovir, Valacyclovir
Definition
A group of antiviral medications used most often to treat herpesvirus
Term
Vesicant
Definition

A drug that causes significant tissue damage when extravasated

 

Term

Extravasation

 

Definition
When a vesicant drug leaks out of the vascular space into the surrounding tissue
Term
Vinca Alkaloids
Definition

Chemotherapy drugs manufactured from the Vinca plant

 

Toxicity: Neurologic Fxn - hearing, constipation

Term

VinCRISTINE

VinBLASTINE

Definition
Vinca Alkaloids
Term

Doxorubicin

Adriamycin

 

The "RED DEVIL"

Definition

An antitumor antibiotic

Strong Vesicant

Turns urine red, total alopecia

Very damaging to tissues if extravasates 

[image]

Term

Cyclophosphamide

 

Definition

A chemotherapy that is often used to treat cancers as well as an immunosuppressant in autoimmune diseases

 

May cause hemorrhagic cystitis (bladder bleeds)

Must keep well hydrated

Term

5-fluoracil

5-FU

Definition

Chemotherapy used most often for GI/Biliary cancers

May cause severe stomatitis

[image]

Term
Methotrexate
Definition

A chemotherapy drug used to treat cancer, autoimmune disease (immunosuppressant) and ectopic (tubal) pregnancy

 

If given in high doses, patients must receive a rescue agent to block the effects after a certain time period

Term
Leucovorin Calcium
Definition

The rescue agent used when high-dose methotrexate is given.  MUST be given ON TIME.

 

Prolonged exposure to methotrexate can cause death

Term
Ifosfamide
Definition

An alkylating agent chemotherapy used for cancer treatment

May cause hemorrhagic cystitis

 

Must be treated with a rescue agent if given in high doses

 

Term
Superinfection
Definition
A secondary infection occurring after treatment for a primary infection Ex. yeast infections or C. diff after use of broad spectrum antibiotics
Term
Monoamine Oxidase Inhibitor
Definition
A class of drugs that when used in Parkinson's Disease inhibits the breakdown of dopamine in the brain
Term
Dopaminergic
Definition
A drug used to mimic the effects of dopamine or that is converted to Dopamine in Parkinson's Disease
Term
Dopamine Agonist
Definition
A class of drugs used to make dopamine receptors more sensitive to Dopamine - these drugs enhance the effects of Dopamine
Term
Anticholinergics
Definition
A class of drugs that inhibit the effects of acetylcholine.  Used in Parkinson's Disease to decrease muscle tremors and rigidity and to decrease drooling. 
Term
Levodopa
Definition
A dopaminergic that converts to dopamine in the brain.  Reduces the symptoms of Parkinson's Disease
Term
Seligiline
Definition
monoamine oxidase inhibitor
Term
Carbidopa
Definition
Used with levadopa as a dopamine agonist
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