Term
PHENYLEPHRINE (NEO SYNEPHRINE)
CLASS: ADRENERGENIC AGENT (SYMPATHOMIMETIC)
ACTION: ALPHA ADRENERGIC AGONIST REDUCES NASAL CONGESTION BY CONSTRICTING SMALL BLOOD VESSELS IN TEH NASAL MUCOSA.
PREG C CATEGORY
ADVERSE RX REBOUND CONGESTION, DO NOT USE WITH MAO INHIBITORS
OVERDOSE: TACHYCARDIA, HTN
TX WITH ALPHA BLOCKER PHENTOLAMINE |
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Definition
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Term
PRAZOSIN
CLASS: ANTIHYPERTENSIVE ADRENERGIC BLOCKING AGENT
SELECTIVE ALPHA ADRENERGIC ANTAGONIST THAT COMPETES WITH NOREPINEPHRINE AT ITS RECEPTORS ON VASCULAR SMOOTH MUSCLE IN ARTERIOLES AND VEINS. MAJOR ACTION RAPID DECREASE IN PERIPHERAL RESISTANCE THAT REDUCES BLOOD PRESSURE. MINIMAL EFFECT ON CARDIAC OUTPUT.
GIVE LOW FIRST DOSE TO AVOID HYPOTENSION
PREG. CATEGORY C |
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Definition
ADVERSE RX: ORTHOSTATIC HYPOTENSION, LIGHT HEADEDNESS
DRUG/DRUG: ANTIHYPERTENSIVES/DIURETICS CAUSE DECREASE IN BP
OD: USE NS OR DOPAMINE OR DOBUTAMINE |
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Term
BETHANECHOL DUVOID, URECHOLINE
NONOBSTRUCTIVE URINARY RETENTION AGENT
ACTION: DIRECT ACTING PARASYMPATHOMIMETIC INTERACTS WITH MUSCARINIC RECEPTORS CAUSING TYPICAL PARASYMPATHETIC STIMULATION. STIMULATES SMOOTH MUSCLE CONTRACTION.
NEVER GIVE IM OR IV
ADVERSE EFFECTS: DO NOT USE IN PT WITH COPD, INCREASED GI TRACT CONTRACTIONS, URINARY OBSTRUCTION. CAUSES INCREASED SALIVATION, SWEATING, ABD. CRAMPING AND HYPOTENSION |
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Definition
DRUG-DRUG: INCREASED CHOLINERGIC EFFECTS FROM CHOLINESTERASE INHIBITORS AND DECREASED CHOLINERGIC EFFECTS FROM PORCAINAMIDE, QUINIDINE, ATROPINE AND EPINEPHRINE.
LABS: CAN INCREASE ast, AMYLASE, LIPASE
TX OF OD: ATROPINE SULFATE |
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Term
ATROPINE (ATRO PEN, ATROPAIR, ATROPISOL)
THERAPUTIC CLASS:ANTIDOTE FOR ANTICHOLINERASE POISIONING
ACTION: BLOCKS THE PARASYMPATHETIC ACTIONS OF Ach AND INDUCES S/S OF FIGHT OR FLIGHT
NEVER GIVE IM MONITOR VS
ADVERSE RX: DRY MOUTH CONSTIPATION, URINARY RETENTION, INCREASED HEART RATE
CONTRAINDICATIONS: GLAUCOMA, PT WITH GI OBSTRUCTIVE DISORDERS, BPH, CARDIAC INSUFFICIENCY |
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Definition
DRUG/DRUG: INCREASED EFFECT WITH ANTIHISTAMINES, TRICYCLIC ANTIDEPRESSANTS, QUINIDINE, PROCAINAMIDE. DECREASES EFFECTS OF DOPAMINE
TX OF OD: GIVE VALIUM |
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Term
Escitalopram Oxalate (Lexapro)
ANTIDEPRESSANT ANXIOLYTIC
stop all MAOI 14d prior, preg category C increase weekly.
DRUG/Drug: no breast feeding, avoid alcohol. |
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Definition
| SSRI increases avail seritonin, selective inhibition results in antidepressive behavior. tx panic disorders |
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