Term
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Definition
The elimination of drugs from the body. |
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Term
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Definition
A- studies indicate no risk to fetus B- studies indicate no risk to animal fetus C- adverse effects reported in animal fetuses; weigh risk/benefit D-possible fetal risk in humans reported; weight risk/benefits X-fetal abnormalities reported and drugs should not be used in pregnant women (or animals) |
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Term
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Definition
5 categories. Resistrictions of use for drugs and whether or not the treatment has an accepted medical use. Potential for abuse is reported. Must have prescription. |
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Term
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Definition
No medical use, need protocol, high abuse, severe dependency (e.g., heroin) |
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Term
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Definition
Accepted use, high abuse, severe physical/psych dependency (e.g. demerol)
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Term
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Definition
Accepted use, less abuse than C-II, less dependency (e.g. codeine, nonopiod preparations) |
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Term
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Definition
Accepted use, less abuse than C-III (e.g. benozodiazepines)
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Term
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Definition
Accepted use, less abuse than C-IV (e.g. cough preparations, lomotil)
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Term
Life Span Considerations for Geriatric |
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Definition
Polypharmcy Multiple meds cause problems with delivery times Higher chance of drug to drug interactions Compliance issues (forgetting, finances) Increase for toxicity (due to hydration, body fat/lean muscle mass, excretion abilities, metabolism rates) |
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Term
Life Span Considertions for Pediatrics |
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Definition
Dose calculations BSA/mg/kg Difficulty in administration Evaluate response Toxicity |
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Term
Life Span Considerations for Pregnant Women |
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Definition
FDA ratings (A,B,C,D-X) Drugs pass/or don't pass through placenta Teratogenesis ETOH, drugs, caffeine |
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Term
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Definition
Nuclear Organelle Plasma membrane |
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Term
Functions of Cell Membrane |
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Definition
Control composition of enclosed space Cellular recognition Cellular mobility Cellular shape |
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Term
Characteristics of a membrane |
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Definition
Not solid Not still Stucture contains (Lipid bilayer, Proteins) Always changing |
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Term
Membrane transport by proteins |
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Definition
Receptors (recogniton and binding) Pores (ion channels); electrolytes Specific carriers for amino acids and monosaccharides Specific enzymes (Sodium Potassium Pump) |
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Term
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Definition
ATP Oxidative Phosphorylation Anaerobic Vs. Aerobic Metabolism |
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Term
Blood Brain Barrier Functions |
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Definition
Protect brain from foreign substances Allow hormones and neurotransmitters to work in rest of body without effecting brain Maintain a constant environment for the brain |
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Term
Characteristics preventing passage through BBB |
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Definition
Large molecular size Low lipid solubility Highly charged molecules |
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Term
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Definition
Hypertension Inflammation Development Pressure Hyperosmolity Radiation Infection Trauma Ischemia |
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Term
Charateristics of Tissue Aging |
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Definition
Progressive stiffening Decreased responsiveness to hormones Decreased muscle mass Decreased height Body fat increase Body water decrease |
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Term
How do cells communicate? |
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Definition
Gap Junctions Hormonal secretions Neurotransmitter secretion Neurohormone secretion Transiet direct lineup of cell |
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Term
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Definition
Autolysis Necrosis Apoptosis |
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Term
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Definition
A change in sensation, awareness, or behavior brought about by a brief electrical disturbance in the brain.
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Term
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Definition
A neurological condition that makes a person more susceptible to having seizures.
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Term
Percentage of Americans to experience a sezuire in their lifetime. |
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Definition
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Term
Possible factors causing uncontrolled nerve activity associated with a seizure. |
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Definition
Head trauma genetic factors fever fever infection ingestion of toxin electrolyte disturbances (and others) |
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Term
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Definition
Seizure that cuases abnormal activity in a specific portion of the brain. |
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Term
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Definition
Seizure that affects the entire brain. |
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Term
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Definition
Seizure that does not affet one's memory or awareness. |
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Term
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Definition
Seizure that affects awareness, behavior, and memories from the time before the seizure all the way through to events immediately following it. |
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Term
Tonic-Clonic Seizure "Grand mal" |
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Definition
Seizure starts with stiffening of the limbs (tonic) followed by jerking of the limbs and face (clonic)
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Term
Absence Seizure "Petit mal" |
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Definition
Seizure with lapses of awareness that last only a few seconds with no warning or after-effect. |
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Term
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Definition
Seizure with sudden loss of muscle tone. |
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Term
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Definition
Seizure with muscle contractions that usually occur at the same time bilaterally.
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