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UMB Pediatric Pharmacology - INF Disease
P3 - Exam1
40
Pharmacology
Professional
10/03/2016

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Cards

Term
3 phases of pertussis
Definition
1. Cartarrhal - <3wks Most contagious
2. Proxysmal - 3-6wks
3. Convalescent >6wks
Term
4 ways to treat pertussis
Definition
1. SMZ/TMZ (Bactrim)
2. ***Azithromycin***
3. Erythromycin
4. Clarithromycin
Term
Can pertussis be prevented with a vaccine?
Definition
YES - DTaP
Term
What causes pertussis
Definition
Bordetella pertussis
Term
Common name for pertussis?
Definition
Whooping cough
Term
Common azithromycin dosing for pertussis
Definition
10mg/kg/day
Term
What is the only pertussis treatment option for neonates?
Definition
Azithromycin
Term
What bacteria is the most common cause of an UTI?
Definition
E.coli 80% of cases
Term
Oral treatment options for an UTI
Definition
7-14 days of:

1. Augmentin 20-40mg/kg/day
2. Bactrim 6-12/20-60mg/kg/day
3. Cephlasporin
Term
What is pyuria IRT UTI?
Definition
Painful urination
Term
3 types of UTI pathogenesis
Definition
1. Ascending (outside in)
2. Descending (inside out)
3. Lymphatic = rare
Term
How is UTI diagnosed?
Definition
1. Pyuria
2. 50,000 colonies/mL of one organism
Term
Typical bacterial causes of sinusitis or Otitis Media?
Definition
1. H influenza
2. S pneumonia
3. M. catarrhalis
Term
Optimal oral/IV agent for treating sinusitis?
Definition
Oral - Amoxicillin 45mg/kg/day
IV - Ceftriaxone
Term
Signs symptoms of sinusitis?
Definition
ache in upper jaw/teeth
cough worsening at night
Bab breath
Term
What is RSV? When is it likely to occur?
Definition
Lower RTI
Jan-Feb in northern hemisphere
Term
Symptoms/clinical manifestations of RSV
Definition
Apnea
LRTI
Wheezing
Comorbid bact. inf.
ADH secretions ---->HYPOnatremia
Term
Agents of RSV treatment
Definition
Bronchodilators
Corticosteroids
Nebulized hypertonic saline
Term
At what age does CAP become more likely to be bacterial than viral?
Definition
5yo
Term
At what age does CAP become more likely to be bacterial than viral?
Definition
5yo
Term
Healthy immunized children >5yo who contract CAP should be treated with what drug?
Definition
Amoxicillin
Term
When/how should Augmentin be used to treat CAP
Definition
If not fully immunized (missing HIB/Flu)
Treat w/ 90mg/kg/day to cover resistant bugs
Term
When should Azythromycin be used to treat CAP/?
Definition
Atypical - chlamydia
Term
Signs symptoms of CAP
Definition
cough
fever
congestion
headache
arthralgia
pleural/ab pain
Term
3 situations in which CAP is treated inpatient
Definition
1. Hypoxemia (SpO2<90%)
2. <3-6mo
3. MRSA
Term
Can CAP be prevented via vaccine?
Definition
yes

s.pneumoniae
HIB
TDAP
Term
What other infection involves the same organism and treatments as Otitis media?
Definition
Sinusitis
Term
Symptoms of otitis media
Definition
1. ear pain (Otalgia)
2. fever
3.Sleep problems
Term
How do patients present with Epiglotis?
Definition
Tripod stance
stridor
Term
Is epiglottitis preventable?
Definition
Yes. Vaccine to HIB
Term
What is the go-to-drug for the treatment of epiglottitis?
Definition
cefotaxime 50/mg/kg/day IV TID for 7-10days
Term
If child has HIB vaccine what are some other likely cause of epiglottitis?
Definition
strep
s. aureus
h. influenza Type A or F
Term
T/F epigoltitis is serious and patients should be sent to the ER?
Definition
True - intubate if symptoms have been present for >24hr
Term
What other ways can epiglottitis be treated?
Definition
For 7-10 days:
ceftriaxone 50mg/kg/day IV
(MRSA) Clindamycin 10mg/kg IV QID
(Clynda-RES-MRSA) vancomycin
Term
What distinctive symptom identifies croup?
Definition
Barking cough in middle of the night
Term
What other peds inf. disease might be Easily confused with croup?
Definition
EPIGLOTITIS
Term
T/F Croup is an URI?
Definition
True
Term
Add what age range is croup most common?
Definition
3mo-3yr
Term
What is the go-to-treatment for Croup?
Definition
Dexamethasone 0.6/mg/kg IV/PO
Term
What signs indicate severe croup, and what treatment should be started?
Definition
Cyanosis. Start Epinephrine nebulization
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