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UMB Pediatric Pharmacology- HTN
P3 - Exam 1
26
Pharmacology
Professional
10/03/2016

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Cards

Term
Define Peds HTN
Definition
BP on 3 occasions >95th percentile for:
- height
- weight
- gender
Term
Two ways to define peds pre HTN
Definition
Either criteria:
1. 90-94th percentile BP
2. 120/80 regardless of percentile
Term
Define peds stage I HTN
Definition
SBP and/or DBP > 95-99th percentile +5mmHg
Term
Define peds stage II HTN
Definition
SBP and/or DBB > 99th percentile +5mmHg
Severe if symptoms presnt
Term
Define neonatal HTN
Definition
>99th percentile
Term
What is the difference between white coat syndrome and masked HTN
Definition
White coat = BP higher in clinic but fine otherwise
Masked = lower in clinic, but hig otherwise
Term
Primary risks of peds HTN
Definition
CDV CKD
Term
What is the preferred method of determining peds BP?
Definition
Auscultation
Term
T/F right arm is preferred?
Definition
T to avoid false low levels due to coarctation of aorta
Term
In normal pt population when do we start checking BP, and how often thereafter
Definition
3 years old. Annually thereafter.
Term
Most common risk factor for peds HTN?
Definition
Obesity (30% over weight children)
Term
Risk factors for peds HTN
Definition
1. Heredity
2. Male
3. Smoke
4. Maternal HTN during preg.
5. Race AA, Mexican
Term
Secondary HTN/ is normally caused by what etiologies?
Definition
1. Cardio
2. Renal
3. Endocrine
Term
Treatment goals in peds HTN
Definition
Normal: BP<95th percentile
w/ comorbidities: BP<90th percentile
Term
What drugs are commercially available in susp/sol form?
Definition
1. Enalapril (vasotec)
2. Furosemide (Lasix)
3. chlorothiazide (Diuril)
Term
What compelling indication would lead you to prescribing CCBs or BBs?
Definition
Migraines
Term
What compelling indication would lead you to prescribing BB or diuretics?
Definition
HF
Term
What compelling indication would lead you to prescribing ACEIs or ARBs?
Definition
Renal, DB,
Term
What is the recommended follow up time when prescribing BP meds
Definition
4-8 weeks
Term
Walk through the dose adjustment flow chart
Definition
1. recommended dose
2. increase to target BP or max dose is reached
3. 2nd drug (complementary MOA)
4. 3rd drug or find an expert
Term
HTN emergency v. urgency
Definition
emergency = severe symptomatic elevation + evidence of target organ damage

Urgency = NO evidence of target organ damage
Term
How to treat HTN urgency?
Definition
reduce BP over 1-2 days
Term
Hot to treat HTN emergency?
Definition
Reduce BP 25% in 8 hours, then slow speed to reach goal in 1-2 days
Term
What agent to treat severe HTN IV?
Definition
Labetalol (bolus or infusion)
Nicardipine (infusion)
Hydralazine (bolus)
Esmolol (infusion)
Sodium nitroprusside (infusion
Term
Which agent treat severe HTN orally?
Definition
Clonidine
Isradipine
Minoxidil
Term
When is pharmacotherapy indicated for peds HTN?
Definition
1. Severe symptomatic HTN
2. Secondary HTN w/ identifiable cause
3. HTN that does not respond to lifestyle changes
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