| Term 
 | Definition 
 
        | pH < 4 in esophagus for >15 sec |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | 1. Physiologic 2. Functional
 3. Pathogenic (FTT)
 4. Secondary unresponsive to treatment
 |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | 1. Emesis 2. Esophagitis
 3. Infant spells (presents seizure-like)
 Respiratory
 4. Sandifer's syndrome (neck tilting)
 |  | 
        |  | 
        
        | Term 
 
        | Why is reflux more common in infants? |  | Definition 
 
        | 1. Slowed gastric emptying 2. LES pressure is less
 3. Esoph. Peristalis
 |  | 
        |  | 
        
        | Term 
 
        | What is the gold standard dx of GERD |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What are 3 methods to dx GERD? |  | Definition 
 
        | 1. Barium swallow 2. Biopsy
 3. Intra-esoph pH monitor (pH probe)
 |  | 
        |  | 
        
        | Term 
 
        | Nonpharm treatment of GERD |  | Definition 
 
        | 1. position change 2. Avoid second-hand smoke
 3. Alter feeding
 4. Avoid some foods
 |  | 
        |  | 
        
        | Term 
 
        | What type of foods should be avoided in GERD? |  | Definition 
 
        | 1. Foods that decrease LES tone 2. Foods that in gastric acid (fatty, citrus, tomato, coffee, soda, alcohol
 |  | 
        |  | 
        
        | Term 
 
        | What type of meds should be avoided in GERD? |  | Definition 
 
        | 1. anticholinergics 2. xanthines(caffeine)
 3. CCB
 4. prostaglandins (NSAIDS)
 |  | 
        |  | 
        
        | Term 
 
        | How can feeds be altered to treat GERD? |  | Definition 
 
        | 1. Thicken with rice 2. Smaller portions
 3. Change formula type to soy or elemental
 |  | 
        |  | 
        
        | Term 
 
        | Describe the Nissen Fundoplication surgery |  | Definition 
 
        | Wrap stomach around the espoh. to increase pressure |  | 
        |  | 
        
        | Term 
 
        | First-line med for GERD and typical dosing in PEDs? |  | Definition 
 
        | H2 (ranitidine, famotidine) Start aggressive 8-10mg/kg/day
 |  | 
        |  | 
        
        | Term 
 
        | What is the common duration of pharm treatment in peds for GERD? |  | Definition 
 
        | ~6mo and then wean as LES has likely gotten stronger, and the meds are no longer needed |  | 
        |  | 
        
        | Term 
 
        | T/F there is evidence for treating infants with PPI? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | When should a PPI be administered? |  | Definition 
 
        | 30min before meal. Do not worry about first feeding of the day or middle of the night feeding.
 |  | 
        |  | 
        
        | Term 
 
        | Where is Erythromycin's place in peds GERD treatment? |  | Definition 
 
        | Older kids | other treatments failed |  | 
        |  | 
        
        | Term 
 
        | What is a side effect of Bethanechol? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What prokinetic agents are available for treating peds GERD? |  | Definition 
 
        | Bethanechol Erythromycin
 Metoclopramide (no longer used)
 Cisapride(discontinued)
 |  | 
        |  | 
        
        | Term 
 
        | CASE 1: 4mo presents to pharmacy.  Cranky all the time.  No fever.  what questions need to be asked? |  | Definition 
 
        | 1. How long? 2. Teething?
 3. Describe feeding
 4. Describe bowel movements
 5. Describe vomitting
 6. Medications?
 7. GERD symptoms?
 |  | 
        |  | 
        
        | Term 
 
        | Describe GERD esophagitis symptoms |  | Definition 
 
        | 1. chest pain 2. Irritability
 3. Feeding trouble
 4. Anemia
 5. Hematemesis
 6. Esoph obstruction
 |  | 
        |  | 
        
        | Term 
 
        | Describe GERD respiratory symptoms |  | Definition 
 
        | 1. recurring pneumonia 2. Wheezing
 3. Apnea
 4. Stridor
 5. Cough
 6. Hiccups
 |  | 
        |  | 
        
        | Term 
 
        | Case 1: Baby has signs of GERD (cries after feeding turns head away, arches back while feeding, spit-up w/ crying) Hieght/weight are normal |  | Definition 
 
        | Star with non-pharm 1. thicker feeds
 2. smaller feeds
 3. change formula type
 3.
 |  | 
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