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| Prevents falling when suddenly standing on one foot |
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| Concerted Activity of Many neurons |
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| Antibodies interefere w/ nicotinic ACh Receptors |
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| Cortical inputs into ____ |
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| Area 6 is ___ in Ready Set GO |
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| Equilibirum potential determined by |
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| Selective Ion permiability and__ |
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| function and assembly of microtubles |
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| effector proteins and intracellular 2nd messangers |
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| Na+ 150, Cl- 150, K 5, CA2+ 2 |
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Observation, Replication, Interpretation, Verification, |
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Nissl - Stain nuclei Golgi - stain neurons |
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DNA -> Transcription -> RNA to mRNA -> mRNA leaves nuclei -> Translation Transcription - RNA polymerase binds to promotor, ends at termination 3'-5' Translation - mRNA gets read by ribosomes 5'-3' |
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Microtubules - 20nm, longditudinal down neurites Microfilaments - 5nm, made of actin, through neurites Neurofilaments - 10nm, only in neurons, skeleton |
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Vesicles walk down axon Kinesin - antergrade transport soma->terminal Dyenein - retrograde transport terminal->soma |
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Stellate - star shaped pyramidal - pryamid shaped unipolar- 1 neurite bipolar - 2 neurites multipolar - multiple neurites |
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Astrocytes - Most numerous, fills space between neurons, influence growth and retraction, removes left over neurotransmitters, controls extracellular fluid contents Myelinating - oligodendrogal and schwan cells form myelin sheeth Ependymal - lining for fluid filled ventricles Microglial - act as phagocytes |
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Threshold - minimum requirment to cause AP, Voltage gated Na+ Channels Open Rising phase - inward rush of Na+ rapid depolarization Overshoot - Membran pot. go more positive Falling Phase - Na+ gates close, K+ open, K+ rushes into cell Undershoot - The rush of K+ causes mp to go more negative, the (-) causes K+ channels to close Absolute Refractory Period - Both channels close no AP until -65mV Relative Refractory Period - waiting for for K+ channels to close |
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Orthodromic - Ap travels down the Axon Antidromic - Ap travels backward up the Axon |
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| Occur in Gap Junctions, allows flow from 1 cell directly to another, bidirectional |
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Occur in synaptic clefts, 20 - 50nm wide, Greys Type I - membrane postsynaptic is thicker than Presynaptic Grays Type II - Membrane is same thickness |
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| Na+ bind to G-protein-receptor which relese G-protein, move about the membrane internally in the cell, active effector enzymes which create 2nd messangers, |
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| inhibition of cAMP formation |
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The subtype of glutamate metabotropic receptor that inhibits cAMP formation may
activate Gi. This is the mechanism used by the NE receptor subtype called a2, which inhibits
adenylyl cyclase and, consequently, inhibits cAMP formation. |
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