Term
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Definition
| Retinoblastoma, osteosarcoma |
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Term
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Definition
Breast
BRCA2 Breast and Ovarian |
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Term
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Definition
most human cancers
Acts through p21 to cause cell cycle arrest
Involved in the G1/S checkpoint and G2/M checkpoint
Can cause apoptosis of mutated cells with pro-apoptotic genes such as BAX |
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Term
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Definition
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Term
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Definition
| Colorectal Cancer (associated with familial adenomatous polyposis) |
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Term
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Definition
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Term
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Definition
Neurofibromatosis type 1
Neurofibromatosis type 2 - with acoustic neuroma |
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Term
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Definition
Pancreatic cancer
"Deleted pancreatic cancer" tumor suppressor |
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Term
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Definition
Colon Cancer
"deleted colon cancer" tumor suppressor |
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