Shared Flashcard Set

Details

Tumor Markers+Chem Carcinogens
FirstAid 2007 p.203-4
19
Medical
Professional
04/30/2008

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Cards

Term
PSA
Definition
prostate-specific Ag; prostatic cancer (screening)
Term
CEA
Definition
carcinoembryogenic antigen; nonspecific but in ~70% of colorectal and pancreatic cancer (also in gastric and breast carcinomas)
Term
AFP (alpha-fetoprotein)
Definition
normal in fetus; expressed in hepatocellular carcinomas, nonseminomatous germ cell tumors of testis (e.g. yolk sac tumor)
Term
beta-hCG
Definition
hydatidiform moles, choriocarcinomas, and gestational trophoblastic tumors
Term
CA-125
Definition
ovarian, malignant epithelial tumors
Term
S-100
Definition
melanoma, neural tumors, astrocytomas
Term
alkaline phosphatase
Definition
metastases to bone, obstructive biliary dx, Paget's dx of bone
Term
bombesin
Definition
neuroblastoma, lung and gastric cancer
Term
TRAP
Definition
tartrate-resistant acid phosphatase. Hairy cell leukemia - B-cell neoplasm
Term
CA-19-9
Definition
pancreatic adenocarcinoma
Term
aflatoxin
Definition
liver (hepatocelular carcinoma)
Term
vinyl chloride
Definition
liver (angiosarcoma)
Term
CCl4
Definition
liver (centrilobular necrosis, fatty change)
Term
nitrosamines
Definition
esophagus, stomach
Term
cigarette smoke
Definition
larynx, lung
Term
asbestos
Definition
lung (mesothelioma and bronchogenic carcinoma)
Term
arsenic
Definition
skin (squamous cell carcinoma)
Term
naphthalene (aniline dyes)
Definition
bladder (transitional cell carcinoma)
Term
alkylating agents
Definition
blood (leukemia)
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