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Tubulointerstitial disease
Clinical Medicine Test 3
15
Medical
Graduate
10/03/2010

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Cards

Term
What is often found in the urine with tubuloinsteritial diseases?
Definition
RBCs, WBCs, WBC casts, and proteinuria-loss of low molecular weight proteins instead of albumin
Term
common findings with tubulointerstitial diseases?
Definition
salt wasting, volume depletion
Term
normal anion-gap metabolic acidosis is usually caused by?
Definition
b-lactam antibiotics, especially methicillin
Term
Triad for normal anion gap metabolic acidosis
Definition
1) HTN
2) fever
3) eosinophilia (20% WBC)
Term
association with what is common in NSAID-induced AIN?
Definition
AIN with glomerular lesions
Term
types of drug-induced CIN
Definition
1) analgesic nephropathy
2) NSAID-induced nepropathy
3) Lithium-induced CIN
4) Chemotherapy-induced CIN
5) CIN caused by cyclosporine and tacrolimus
Term
triad associated with acute bacterial pyelonephritis
Definition
1) Pyuria
2) hematuria
3) WBC casts

Positive urine cultures usually present
Term
chronic pyelonephritis is most commonly the result of?
Definition
repeated bacterial infections complicating vesicoureteral reflux
Term
kidney findings often associated with chronic pyelonephritis
Definition
contracted and scarred
Term
diagnosis of lead-induced nephrotoxicity made by?
Definition
elevated lead urine levels after IV/IM EDTA injection
Term
focal ischemia and infarction from sickle cell anemia is most commonly found in what area of the kidneys?
Definition
vasa recta of the renal medulla
Term
Interstitial diseases associated with vascular damage what are they?
Definition
1) hypertension
2) sickle cell anemia
3) cholesterol
4) renal vein thrombosis
Term
most with multiple myeloma present with?
Definition
proteinuria
Term
what do 90% of people have with polycystic kidney disease?
Definition
abnormal gene on the short arm of chromosome 16
Term
What conditions did most people take NSAIDs for with NSAID-induced nephropathy?
Definition
1) headaches
2) arthritis
3) backache
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