Term
|
Definition
Streptomycin
Isoniazid (Tubizid®)
Ethambutol (Myambutol®)
Rifampin (Rifadin®)
Pyrazinamide |
|
|
Term
|
Definition
No Brand Name
MOA: Bactericidal; Binds to bacterial 30S ribosomal subunit, inhibiting protein synthesis
NOTE: Thompson said this is 2nd line treatment
Aminoglycoside |
|
|
Term
|
Definition
Tubizid®
MOA: Bactericidal; Inhibits lipid and nucleic acid synthesis
Anti-tuberculosis |
|
|
Term
|
Definition
Myambutol®
MOA: Inhibits metabolite synthesis
Anti-tuberculosis |
|
|
Term
|
Definition
Rifadin®, Rimactane®
MOA: Inhibits DNA-dependent RNA polymerase
Anti-tuberculosis |
|
|
Term
|
Definition
No Brand Name
MOA: Converted to pyrazinoic acid in susceptible strains of Mycobacterium which lowers the pH of the environment
Anti-tuberculosis |
|
|
Term
|
Definition
Cycloserine (Seromycin® Pulvules)
Para-amino salicyclic acid
Ethionamide (Trecator-SC®)
Ciprofloxacin (Cipro®)
Levofloxacin (Levaquin®)
Mofloxacin (Avelox®)
Ofloxacin (Floxin®)
Amikacin (Amikin®)
Capreomycin (Capastat® sulfate)
Linezolid (Zyvox®)
Rifabitin (Ansamycin®)
Rifapentine (Priftin®) |
|
|
Term
|
Definition
Seromycin® Pulvules
MOA: Bactericidal or bacteriostatic; Inhibits cell wall synthesis
Anti-tuberculosis |
|
|
Term
Para-amino salicyclic acid |
|
Definition
No Brand Name
MOA: Inhibits folic acid synthesis and inhibits synthesis of cell wall component, mycobactin, thus reducing iron uptake by M. tuberculosis
Anti-tuberculosis |
|
|
Term
|
Definition
Trecator-SC®
MOA: Inhibits peptide synthesis
Anti-tuberculosis |
|
|
Term
|
Definition
Cipro®
MOA: Bactericidal; inhibits DNA gyrase and topoisomerase IV
Fluoroqunolone |
|
|
Term
|
Definition
Levaquin®
MOA: Bactericidal; inhibits DNA gyrase and topoisomerase IV
Fluoroquinolone |
|
|
Term
|
Definition
Avelox®
MOA: Bactericidal; inhibits DNA gyrase and topoisomerase IV
Fluroquinolone |
|
|
Term
|
Definition
Floxin®
MOA: Bactericidal; inhibits DNA gyrase and topoisomerase IV
Fluroquinolone |
|
|
Term
|
Definition
Amikin®
MOA: Bactericidal; Binds to bacterial 30S ribosomal subunit, inhibiting protein synthesis
Aminoglycoside |
|
|
Term
|
Definition
Capastat® Sulfate
MOA: A cyclic polypeptide antimicrobial
Anti-tuberculosis |
|
|
Term
|
Definition
Zyvox®
MOA: Binds to 50S ribosomal subunit, interfering with protein synthesis
Antibiotic |
|
|
Term
|
Definition
Ansamycin®
MOA: Inhibits DNA-dependent RNA polymerase
Anti-tuberculosis |
|
|
Term
|
Definition
Priftin®
MOA: Inhibits DNA-dependent RNA polymerase
Anti-tuberculosis |
|
|
