Term
| Can either the peripheral or central nervous system regenerate? |
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Definition
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Term
| What is the role of a neuromuscular junction? |
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Definition
| It uses ACh to connect nerves to muscles |
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Term
| What kind of receptor is the ACh receptor? |
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Definition
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Term
| How many subunits is the ACH receptor comprised of? |
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Definition
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Term
| What is the role of the alpha subunits in the ACH receptor? |
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Definition
| They bind ACh. 2 molecules are required |
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Term
| How does muscle depolarisation occur? |
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Definition
| The ACh receptor causes a K+ efflux and Na + influx via a non-selective cation channel |
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Term
| What is a skeletal muscle depolarisation called? |
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Definition
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Term
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Definition
| It binds to ACh receptors and is used to achieve surgical paralysis |
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Term
| What does botulinum toxin do? |
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Definition
| Prevents ACh release from vesicles and is used locally to treat dystonia |
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Term
| What does myasthenia gravis do? |
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Definition
| It is an antibody against the ACH receptor and block transmission causing weakness and fatigue |
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