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trueger
pulm pharm
40
Medical
Graduate
05/12/2006
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Term
LOX ->?
 Definition
leukotrienes
Term
?-> leukotrienes
 Definition
LOX ->?
Term
LTB4
 Definition
PMN chemotactant
Term
PMN chemotactant
 Definition
LTB4
Term
LTC3, D4, E4
 Definition
bronchocontstr
vasoconstr
sm musc contr
up vasc perm
Term
LTB,C,D
 Definition
up bronchial tone
Term
up bronchial tone (factors)
 Definition
LTB,C,D
Term
bronchocontstr
vasoconstr
sm musc contr
up vasc perm

up bronchial tone

 Definition
LTC3, D4, E4
Term
PGI2
 Definition
inh platelet aggr
vasodiln
Term
inh platelet aggr
vasodiln
 Definition
PGI2
Term
CS as resp pharm
 Definition
dn PLA2
dn COX synth
beclomethasone, prednisone
via dn TNFa
Term
Zileuton MOA
 Definition
inh LOX
Term
zafirlukast
 Definition
inh leukotriene R
Term
montelukast
 Definition
inh leukotriene R
Term
PGI
 Definition
dn platelet aggr
dn vasc tone
dn bronch tone
dn uterine tone
Term
dn platelet aggr
dn vasc tone
dn bronch tone
dn uterine tone
 Definition
PGI
Term
PGE&PGF
 Definition
up uterine tone
dn vasc & bronch tone
Term
up uterine tone
dn vasc & bronch tone
 Definition
PGE&PGF
Term
TXA
 Definition
up platelet aggr
up vasc&bronch tone
Term
up platelet aggr
up vasc&bronch tone
 Definition
TXA
Term
H1 blockers - 1st gen
 Definition
diphenhydramine
dimenhydrinate
chorpheniramine
Term
H1 blockers - 1st gen Rx
 Definition
allergy
motion sickness
sleep aid
Term
H1 blockers - 2nd gen
 Definition
loratadine
fexofenadine
desloratadine
Term
allergy
motion sickness
sleep aid
 Definition
H1 blockers - 1st gen Rx
Term
diphenhydramine
dimenhydrinate
chorpheniramine
 Definition
H1 blockers - 1st gen
Term
H1 blockers - 1st gen SE
 Definition
sedn
antimusc
anti-a-adrenergic
Term
sedn
antimusc
anti-a-adrenergic
 Definition
H1 blockers - 1st gen SE
Term
H1 blockers - 2nd gen Rx
 Definition
allergy
Term
loratadine
fexofenadine
desloratadine
 Definition
H1 blockers - 2nd gen
Term
isoproterenol for asthma
 Definition
B2ag-> relax broncSM
but tachy (B1)
Term
albuterol
 Definition
B2 ag
use during acute asthma attack
Term
salmeterol
 Definition
long acting B2 ag for asthma prophylaxis
SE: tremor, arrhythm
Term
B2 ag
use during acute asthma attack
 Definition
albuterol
Term
long acting B2 ag for asthma prophylaxis
SE: tremor, arrhythm
 Definition
salmeterol
Term
theophylline
 Definition
inh phosphodiesterase -> dn cAMP hydrolysis
narrow ther window (card & neurotox)
Term
inh phosphodiesterase -> dn cAMP hydrolysis
 Definition
theophylline
(methylxanthine)
narrow ther window (card & neurotox)
Term
ipratropium
 Definition
blocks muscR-> prevents bronchoconstr
Term
blocks muscR-> prevents bronchoconstr
 Definition
ipratropium
Term
cromolyn
 Definition
prevents mast cell release of mediators
prophylactic
Term
prevents mast cell release of mediators
prophylactic
 Definition
cromolyn
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