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trueger
mm/ct nl and arthr
42
Other
Not Applicable
05/28/2006
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Term
layers of epidermis
 Definition
basalis, spinosum, granulosum, lucidum, corneum
Term
zona occludens
 Definition
tight jcn
prevents diffusion
Term
zona adherens
 Definition
IM jcn
actin & ecadherin
Term
macula adherens
 Definition
desmosome
small, discrtem keratin & desmoplakin
Term
gap jcns
 Definition
let sm stuff through
Term
integrin
 Definition
bind to BM
hemidesmisome w. ECM
Term
basalis, spinosum, granulosum, lucidum, corneum
 Definition
layers of epidermis
Term
tight jcn
prevents diffusion
 Definition
zona occludens
Term
IM jcn
actin & ecadherin
 Definition
zona adherens
Term
desmosome
small, discrtem keratin & desmoplakin
 Definition
macula adherens
Term
let sm stuff through
 Definition
gap jcns
Term
bind to BM
hemidesmisome w. ECM
 Definition
integrin
Term
intramembr bone formn
 Definition
spon bone formn w.o preexis cart
Term
endochondrial bone formn
 Definition
oss'n of cart
long bones do this at prim & 2nd ctrs
Term
pos anterior drawer sign
 Definition
ACL torn
Term
ACL/PCL naming
 Definition
TIBIAL attachments
Term
abn passive abduction
 Definition
torn MCL
Term
spon bone formn w.o preexis cart
 Definition
intramembr bone formn
Term
oss'n of cart
long bones do this at prim & 2nd ctrs
 Definition
endochondrial bone formn
Term
rotator cuff mm
 Definition
sub scab
supraspin
inf
teres min
Term
skel mm contrn
 Definition
ATP binds myosin, releasing from actin
binds new actin
releases ADP
Term
Ca role in skel mm contrn
 Definition
binds trop C, moving tropomysin out of way
Term
binds trop C, moving tropomysin out of way
 Definition
Ca role in skel mm contrn
Term
dihydropuridine R
 Definition
voltage gated Ca channel on mm
makes ryR go
Term
RYR
 Definition
releases Ca from SR
Term
voltage gated Ca channel on mm
makes ryR go
 Definition
dihydropuridine R
Term
releases Ca from SR
 Definition
RYR
Term
what mm bands contract?
 Definition
HIZ
Term
where are t tubules?
 Definition
AI jcn
Term
sm mm contr
 Definition
Ca binds calmodulin
acts MLCK
myosinP-> cross bridges
Term
myosinP->
 Definition
cross bridges
Term
achondroplasia inher
 Definition
AD
Term
achondroplasia pathophys
 Definition
failure of lg bones to grow -> short limbs
membr oss not affected (skull, face, axial = nl)
Term
achondroplasia "ssx"
 Definition
nl head & trunk w. lil limbs
Term
failure of lg bones to grow -> short limbs
membr oss not affected (skull, face, axial = nl)
 Definition
achondroplasia pathophys
Term
nl head & trunk w. lil limbs
 Definition
achondroplasia "ssx"
Term
OA pathophys
 Definition
mech wear & tear of joints ->destr art cart
subchondral bone formn, sclerosis, osteophytes, eburnation, heberdens nodes & bouchards nodes
Term
heberden & bouchards nodes
 Definition
HD
BP
Term
OA ssx
 Definition
older pts
wt bearing, end of day
improv w. rest
no sys sxs
Term
older pts
wt bearing, end of day
improv w. rest
no sys sxs
 Definition
OA ssx
Term
RA pathophys
 Definition
autoimmune inflamm of synov joints
forms pannus in MCP, PIP
subq rheum nodules, ulnar dev, sublux
Term
RA clin
 Definition
F>M
80% pos rheum factor (anti-IgG Ab)
morning stiff, impr w. use
symm joint involvement, sys sx: F, fatigue, pleuritis, pericarditis
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