Shared Flashcard Set

Details

trueger
GI pharm
56
Other
Not Applicable
05/17/2006

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Cards

Term
what are the H2 blockers
Definition
cimetidine, ranitidine, famotidine, nizatidine
Term
rx moa: dn H+ secrn by par cells
Definition
h2 blocker moa
Term
h2 blocker Rx
Definition
PUD, gastritis, mild GERD Rx
Term
h2 blocker tox
Definition
cimetidine: inh p450 & is antiandro & dn renal excrn of creatinine
Term
cimetidine, ranitidine, famotidine, nizatidine
Definition
what are the H2 blockers
Term
h2 blocker moa
Definition
rx moa: dn H+ secrn by par cells
Term
PUD, gastritis, mild GERD Rx
Definition
h2 blocker Rx
Term
what are the PPIs?
Definition
omeprazole, lansoprazole
Term
PPI MOA
Definition
irrevers inh H/K atpase in parietal cells
Term
PPI clin use
Definition
PUD, gastritis, GERD, ZE
Term
irrevers inh H/K atpase in parietal cells
Definition
PPI MOA
Term
PUD, gastritis, GERD, ZE
Definition
PPI clin use
Term
bismuth & sucralfate MOA
Definition
bind to ulcer base (shield vs acid)
to allow bicarb secrn to reestablish pH gradient
Term
bismuth & sucralfate clin use
Definition
help heal ulcers, traveler's D
Term
triple therapy for h pyl
Definition
metro, amox (or tetr) and bismuth
Term
bind to ulcer base (shield vs acid)
to allow bicarb secrn to reestablish pH gradient
Definition
bismuth & sucralfate MOA
Term
help heal ulcers, traveler's D
Definition
bismuth & sucralfate clin use
Term
misoprostol MOA
Definition
PGE1 analog
up prodn & secrn of gastric mucous barrier
dn acid prodn
Term
misoprostol clin use
Definition
prevent NSAID ulcer
maintain PDA
induce labor
Term
misoprostol SE
Definition
abort
D
Term
PGE1 analog
up prodn & secrn of gastric mucous barrier
dn acid prodn
Definition
misoprostol MOA
Term
prevent NSAID ulcer
maintain PDA
induce labor
Definition
misoprostol clin use
Term
abort
D
Definition
misoprostol SE
Term
what are the musc antags
Definition
pirenzepine, propantheline
Term
pirenzepine, propantheline
Definition
what are the musc antags
Term
omeprazole, lansoprazole
Definition
what are the PPIs?
Term
musc antag MOA
Definition
block M1R on ECL cells -> dn histamine secrn
block M3R on parietal cells ->dn H+
Term
use musc antag
Definition
PUD
Term
musc antag SE
Definition
bradycardia, dry mouth, diff closing eyes
Term
bradycardia, dry mouth, diff closing eyes
Definition
musc antag SE
Term
block M1R on ECL cells -> dn histamine secrn
block M3R on parietal cells ->dn H+
Definition
musc antag MOA
Term
infliximab MOA
Definition
Ab to TNFa
Term
infliximab clin use
Definition
crohns, RA
Term
infliximab SE
Definition
resp inf, F, hypoTN
Term
Ab to TNFa
Definition
infliximab MOA
Term
crohns, RA Rx
Definition
infliximab clin use
Term
resp inf, F, hypoTN
Definition
infliximab SE
Term
sulfasalazine MOA
Definition
sulfapyradine: abx
mesalamine: antiinflammo
actd by colonic bac
Term
sulfapyradine: abx
mesalamine: antiinflammo
Definition
sulfasalazine MOA
actd by colonic bac
Term
sulfasalazine clin use
Definition
UC, crohns
Term
sulfasalazine SE
Definition
malaise, N, sulfa tox, revers oligosperm
Term
UC, crohns RX
Definition
sulfasalazine clin use
Term
malaise, N, sulfa tox, revers oligosperm
Definition
sulfasalazine SE
Term
ondansetron MOA
Definition
5-HT3 inh
powerful central antiemetic
Term
ondansetron clin use
Definition
postob & chemo anti emetic
Term
ondansetron SE
Definition
HA
constipation
Term
5-HT3 inh
powerful central antiemetic
Definition
ondansetron MOA
Term
postob & chemo anti emetic
Definition
ondansetron clin use
Term
HA
constipation
Definition
ondansetron SE
Term
antacid overuse MOA
Definition
affects absorption, bioavail, or urin excrn of Rx
via alt'ng gastric & urin pH
or delaying gastric emptying
Term
AlOH overuse
Definition
constipation
hypophos
hypoK
Term
MgOH overuse
Definition
D
hypoK
Term
CaCO3 overuse
Definition
hyperCa
rebound acidosis
hypoK
Term
constipation
hypophos
hypoK
Definition
AlOH overuse
Term
D
hypoK
Definition
MgOH overuse
Term
hyperCa
rebound acidosis
hypoK
Definition
CaCO3 overuse
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