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trueger
GI path I
82
Other
Not Applicable
05/16/2006

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Term
LES achalasia
s/t chagas (t cruzi)
Definition
bird beak
loss of myenteric plexus
progressive dysphagia
up risk esoph CA
Term
bird beak
Definition
LES achalasia
s/t chagas (t cruzi)
loss of myenteric plexus
progressive dysphagia
up risk esoph CA
Term
IDA in old men
Definition
colonic CA
Term
diaphragmatic hernia
Definition
abd structures enter thorax
infants: result of def dev of pleuroperitoneal membr
us hiatal: stomach through esoph hiatus
Term
indirect inguinal hernia
Definition
internal & external ing rings into scrotum
lateral to inferior epigastric a
infants: failure of process vaginalis to close

m>>f

Term
direct inguinal hernia
Definition
through inguinal (hesselbach's) triangle
bulge directly through abd wall
medial to inf epigastric a
ext ring only

us older men

Term
hesselbach's triangle
Definition
inf epiG a
lat border of rectus abd
ing lig

dir ing hernia

Term
indirect vs direct ing hernia
Definition
MD's LI
medial: direct
Lateral: indirect

(to epigastric a)

Term
meckel's diverticulum
Definition
persistance of vitelline duct or yolk stalk
s/t ectopic gastric muc or pancr tissue
most common GI congen anomaly
can bleed, intussuscept, volvulus, or obstr near terminal ileum
Term
meckel's diverticulum mnemonic
Definition
five 2s:
2 inches
2ft from ileocecal valve
2% of population
first 2 yrs of life
may have 2 types of epith
Term
viral hep labs
Definition
ALT>AST
Term
alcoholic hep labs
Definition
AST>ALT
Term
MI liver labs
Definition
AST only
Term
GGT up
Definition
liver dz
Term
alk phos up
Definition
obstr liver dz (HCC)
bone dz
Term
amylase up
Definition
ac pancr, mumps
Term
lipase up
Definition
ac pancr
Term
dn ceruloplasmin
Definition
wilsons dz lab
Term
ALT>AST
Definition
viral hep labs
Term
AST>ALT
Definition
alcoholic hep labs
Term
AST only
Definition
MI liver labs
Term
liver dz
Definition
GGT up
Term
obstr liver dz (HCC)
bone dz
Definition
alk phos up
Term
mumps lab
Definition
amylase up
Term
ac pancr lab
Definition
lipase up, amylase ups
Term
wilsons dz lab
Definition
dn ceruloplasmin
Term
barrett's esophagus
Definition
glandular columnar epith metaplasia
->adCA
Term
RFs for esoph CA
Definition
Alcohol
Barrett's
Cigarettes
Diverticuli
Esophegeal web (plummer-vinson)
Esophagitis
Familial

->adCA except barretts

Term
congen pyloric stenosis
Definition
hypertroph'd pylorus-> obstr
palpable "olive" mass in epiG region
nonbilious projectile vomit at 2wks
1/600 births
often 1stborn males
tx: surg incision
Term
celiac sprue
Definition
autoAb to gluten (gliadin)
prox sm bowel
Term
tropical sprue
Definition
probably inf's
responds to abx
can affect entire sm bowel
Term
whipple's dz
Definition
inf'n w/ tropheryma whippelii
PAS pos macs in intest LP & mesenteric nodes
Term
disaccharidase def
Definition
us. Lactate
Term
pancr insuff
Definition
CF, chr pancreatitis
malabs fat, protein, ADEK
Term
autoAb to gluten (gliadin)
prox sm bowel
Definition
celiac sprue
Term
probably inf's
responds to abx
can affect entire sm bowel
Definition
tropical sprue
Term
inf'n w/ tropheryma whippelii
PAS pos macs in intest LP & mesenteric nodes
Definition
whipple's dz
Term
CF, chr pancreatitis
malabs fat, protein, ADEK
Definition
pancr insuff
Term
ac gastritis
Definition
erosive
disruption of muc barrier -> inflamm
etios: stress, NSAIDs, etoh, uricemia, burns (curling ulcer) or brain injury (cushing ulcer)
Term
curling ulcer
Definition
fr burns
Term
cushing ulcer
Definition
fr brain injury
Term
TBI-> gastric ulcer
Definition
cushing ulcer
Term
burn-> gastric ulcer
Definition
curling ulcer
Term
chr gastritis type A
Definition
Autoimmune, Autoabs to parietal cells -> pern Anemia and Anchlorhydria
fundal
up risk gastric CA
Term
chr gastritis type B
Definition
H pylori
antral
up risk gastral CA
Term
PUD: gastric
Definition
pain up w/ meals
wt loss
h pyl: 70%
chr NSAIDs
dn mucosal protection vs. gastric acid
Term
PUD: duo
Definition
pain dn w/ meals
wt gain
h pyl: alm 100%
up acid secrn or dn mucosal
hypertrophy brunners
Term
PUD general
Definition
clean, punched out margins (cf. raised/irreg margins of CA)
complns: bleed, penetrations, perf, obstrn
not necc pre-canc
h pyl: tx w. metro, bismuth salicylate, & amox or tetra
s/t PPI also
up inc ww/ smokers
Term
stom CA
Definition
us adCA
early aggr mets: LN & hep
assoc w. nietary nitrosamines, achlorhydria, chr gastritis
linitis plastica: diffusely infiltrative (thick'd, rigid appearance)
Term
virchow's node
Definition
SC LN w. mets fr stomach
Term
krukenberg tumor
Definition
bil gastric mets -> ovaries
mucus "signet ring" cells
Term
bil gastric mets -> ovaries
Definition
krukenberg tumor
Term
Crohns gen
Definition
poss infectious
may involve any portion of GI tract
us term il & colon
skip lesions & rectal sparing
Term
crohns gross
Definition
transmural inflammo
cobblestone mucosa
creeping fat
bowel wall thickening -> string sign
linear ulcers
fissures, fistulas
Term
crohns micro
Definition
noncas granulomas & lymphoid aggrs
Term
crohns complns
Definition
strictures
fistulas
perianal dz
malabs
nutr depletement
Term
crohns extra GI
Definition
migr polyarthritis
erythema nodosum
ankylosing spondylitis
uveitis
immun ds
Term
UC general
Definition
poss autoimmune
colon only, continuous, always rectal & ascs
Term
UC gross
Definition
colon only
muc & submuc only
friable muc pseudopolyps w. free hanging mesentary
lead pipe
Term
UC micro
Definition
crypt abscesses & ulcers
bleeding
no granulomas
Term
UC complns
Definition
severe stenosis
toxic megacolon
colorectal CA
Term
UC extra GI
Definition
pyoderma gangrenosum
PSC
Term
poss infectious
may involve any portion of GI tract
us term il & colon
skip lesions & rectal sparing
Definition
Crohns gen
Term
transmural inflammo
cobblestone mucosa
creeping fat
bowel wall thickening -> string sign
linear ulcers
fissures, fistulas
Definition
crohns gross
Term
noncas granulomas & lymphoid aggrs
Definition
crohns micro
Term
strictures
fistulas
perianal dz
malabs
nutr depletement
Definition
crohns complns
Term
migr polyarthritis
erythema nodosum
ankylosing spondylitis
uveitis
immun ds
Definition
crohns extra GI
Term
poss autoimmune
colon only, continuous, always rectal & ascs
Definition
UC general
Term
colon only
muc & submuc only
friable muc pseudopolyps w. free hanging mesentary
lead pipe
Definition
UC gross
Term
crypt abscesses & ulcers
bleeding
no granulomas
Definition
UC micro
Term
severe stenosis
toxic megacolon
colorectal CA
Definition
UC complns
Term
pyoderma gangrenosum
PSC
Definition
UC extra GI
Term
appendicitis
Definition
all age groups
most common indn for emerg abd surg in kids
diffuse periumb pain ->
loc'd pain at mcburney's pt (midway b/t umb & ASIS =app root)
N, F, may perf-> peritonitis
Term
DDX app'tis
Definition
diverticulitis (elderly)
ectopic preggers (use b-hCG to r/o)
Term
diverticulum
Definition
blind pouch leading of alimentary tract, lined by muc, musc & serosa
comms w/ lumen
false= no or atten'd muscularis externa (esp at vasa recta)
most often: sigmoid
Term
blind pouch leading of alimentary tract, lined by muc, musc & serosa
comms w/ lumen
most often: sigmoid
Definition
diverticulum
Term
diverticulosis
Definition
many diverticula
50% of >60yo
cause: up lumen pressure & focal wall weakness
most often sigmoid
low fiber diets
us asx or vague discomfort, +/- rectal bleed
Term
diverticulitis
Definition
inflam'n of tic-> LLQ pain
complns: perf, peritonits, abscess, bowel stenosis
Term
intussusception
Definition
telescoping of 1 bowel segm into distal segment
can compr BD
often due to luminal mass
Term
volvulus
Definition
twisting of portion of bowel around its mesentery
can -> obstrn & infn

us sigmoid b/c red'd mesentery
Term
hirschsprung dz
Definition
congen megacolon bc lack of both enteric nn plexi
failure of neural crest cells to migrate
early chr constip
risk up w. downs
Term
colorectal CA
Definition
3rd most common
RFs: villous adenomas, chr IBD (esp UC), high fat & low fiber, age, FAP, HNPCC, DCC deln, p&fhx of CR CA
peutz-jeghers- not a RF
screen at 50 y/o w/ FOBT & scope
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