Term
|
Definition
act's antithrombin iii
dn thrombin & xa
short t1/2 |
|
|
Term
|
Definition
immed anti coag for PE, stroke, anginia, MI, DVT
preggers safe
follow: PTT |
|
|
Term
|
Definition
bleed, TCP, RX intrxns
reverse w/ protamine sulfate new LMWH acts on xa, better F, subq w.o ptt but not easily reversible |
|
|
Term
act's antithrombin iii
dn thrombin & xa
short t1/2 |
|
Definition
|
|
Term
immed anti coag for PE, stroke, anginia, MI, DVT
preggers safe
follow: PTT |
|
Definition
|
|
Term
|
Definition
inh synth & gamma carbox of vit k factors: ii, vi, ix, x, protein c & s
extr pathway
up PT |
|
|
Term
inh synth & gamma carbox of vit k factors: ii, vi, ix, x, protein c & s
extr pathway
up PT |
|
Definition
|
|
Term
|
Definition
chr anticoag
don’t use in preggers
follow PT |
|
|
Term
chr anticoag
don’t use in preggers
follow PT |
|
Definition
|
|
Term
|
Definition
|
|
Term
| what are the thrombolytics |
|
Definition
| streptokinase, urokinase, tpa (alteplase), apsac (anistreplase) |
|
|
Term
|
Definition
| dir or indir conv plasminogen->plasmin |
|
|
Term
|
Definition
| early MI, early ischemic stroke |
|
|
Term
|
Definition
bleeding
contraind: active bleeding hx, IC bleed, recent surg, bleeding diastheses, severe HTN
tox tx: aminocaproic acid (inh fibr-lysis) |
|
|
Term
| streptokinase, urokinase, tpa (alteplase), apsac (anistreplase) |
|
Definition
| what are the thrombolytics |
|
|
Term
| dir or indir conv plasminogen->plasmin |
|
Definition
|
|
Term
| early MI, early ischemic stroke |
|
Definition
|
|
Term
bleeding
contraind: active bleeding hx, IC bleed, recent surg, bleeding diastheses, severe HTN
tox tx: aminocaproic acid (inh fibr-lysis) |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| what does exposed collagen bind? |
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
inh COX1&2
dn PGs
up bleeding time
no effect on PT or PTT |
|
|
Term
| clopidogrel & ticlopidine MOA |
|
Definition
irrev bind ADPRs
inh fibrinogen-Gpiib/iiia binding |
|
|
Term
| clin use clopidogrel & ticlopidine |
|
Definition
ac cor syndrome, cor stenting
dn inc/rec of thr stroke |
|
|
Term
irrev bind ADPRs
inh fibrinogen-Gpiib/iiia binding |
|
Definition
| clopidogrel & ticlopidine MOA |
|
|
Term
ac cor syndrome, cor stenting
dn inc/rec of thr stroke |
|
Definition
| clin use clopidogrel & ticlopidine |
|
|
Term
|
Definition
| ab: GP iib/iiia on pltlts |
|
|
Term
|
Definition
| ac cor syndrome, prec transluminal cor angioplasty |
|
|
