Shared Flashcard Set

Details

Tricyclics
Tricyclics
13
Pharmacology
Professional
08/22/2012

Additional Pharmacology Flashcards

 


 

Cards

Term
How do tricyclics work?
Definition

5HT and NE reuptake inhibitors (and block ACh and histamine receptors - which contributes to the SE profile).

Term
List Tertiary amines?
Definition

Amitriptyline

Doxepine

Clomipramine

Imipramine

Trimipramine

 

 

Term
List secondary animes?
Definition

Amoxapine

Desipramine

Maprotiline

Nortriptyline

Protiptyline

 

 

[image][image][image][image]Wikipedia: Nortriptyline is a second-generation tricyclic antidepressant marketed as the hydrochloride salt under the trade names Sensoval, Aventyl, Pamelor, Norpress, Allegron, Noritren and Nortrilen.

Term
What is Amitripyline approved for?
Definition

Neuroapathic pain

Depression

 

Term
What is
Definition
Term
What is Nortriptyline approved for?
Definition
Depression
Term
What is Doxepin approved for?
Definition
Depression
Term
Side effects of Tricyclics
Definition

Cardiotoxicity

 

Anticholinergic - dry mouth, blurred vision, urinary retention, constipation (taper off to avoid cholinergic rebound)

 

Vivid dreams

 

Term
MAOIs and hypertensive crisis?
Definition
2 week washout if going to of from a MAOI
Term
TCAs are metabolized by?
Definition
2D6
Term
TCAs cause constipation?
Definition

Yes. May need to use a stool softener or laxitive if this becomes a problem.

[image][image][image][image]

Term
Can TCAs can dry/blurry vision or urinary problems or dry mouth?
Definition
may cause dry/blurry vision; may make it more difficult to urinate; may cause dry mouth.
Term
Dental problems whilst using TCAs?
Definition

Yes. The dry mouth can contribute to dental decay (cavities) and difficulty chewing food. It is important to use proper dental hygiene when taking any medication that causes dry mouth, including brushing and flossing.

 

 

Supporting users have an ad free experience!