| Term 
 | Definition 
 
        | 5HT and NE reuptake inhibitors (and block ACh and histamine receptors - which contributes to the SE profile). |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Amitriptyline Doxepine Clomipramine Imipramine Trimipramine     |  | 
        |  | 
        
        | Term 
 | Definition 
 
        | Amoxapine Desipramine Maprotiline Nortriptyline Protiptyline     |  | 
        |  | 
        
        | Term 
 
        | What is Amitripyline approved for? |  | Definition 
 
        | Neuroapathic pain Depression   |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is Nortriptyline approved for? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | What is Doxepin approved for? |  | Definition 
 | 
        |  | 
        
        | Term 
 
        | Side effects of Tricyclics |  | Definition 
 
        | Cardiotoxicity   Anticholinergic - dry mouth, blurred vision, urinary retention, constipation (taper off to avoid cholinergic rebound)   Vivid dreams   |  | 
        |  | 
        
        | Term 
 
        | MAOIs and hypertensive crisis? |  | Definition 
 
        | 2 week washout if going to of from a MAOI |  | 
        |  | 
        
        | Term 
 | Definition 
 | 
        |  | 
        
        | Term 
 | Definition 
 
        | Yes. May need to use a stool softener or laxitive if this becomes a problem. |  | 
        |  | 
        
        | Term 
 
        | Can TCAs can dry/blurry vision or urinary problems or dry mouth? |  | Definition 
 
        | may cause dry/blurry vision; may make it more difficult to urinate; may cause dry mouth. |  | 
        |  | 
        
        | Term 
 
        | Dental problems whilst using TCAs? |  | Definition 
 
        | Yes. The dry mouth can contribute to dental decay (cavities) and difficulty chewing food. It is important to use proper dental hygiene when taking any medication that causes dry mouth, including brushing and flossing.     |  | 
        |  |