Shared Flashcard Set

Details

Transport
Cell Environment and Membrane Transport
53
Biochemistry
Undergraduate 1
12/18/2012

Additional Biochemistry Flashcards

 


 

Cards

Term
Which compartment/s make up the extra-cellular fluid?
Definition
Blood plasma AND Interstitial fluid
Term
What is the relative concentration of Na+ in the blood plasma?
Definition
High
Term
What is the relative concentration of Na+ in the interstitial fluid?
Definition
High
Term
What is the relative concentration of Na+ in the intra-cellular fluid?
Definition
Low
Term
What is the relative concentration of K+ in the blood plasma?
Definition
Low
Term
What is the relative concentration of K+ in the interstitial fluid?
Definition
Low
Term
What is the relative concentration of K+ in the intra-cellular fluid?
Definition
High
Term
What is the relative concentration of Cl- in the blood plasma?
Definition
Low
Term
What is the relative concentration of Cl- in the interstitial fluid?
Definition
Low
Term
What is the relative concentration of Cl- in the intra-cellular fluid?
Definition
Almost Non-existant
Term
What is the relative concentration of Ca2+ in the blood plasma?
Definition
High
Term
What is the relative concentration of Ca2+ in the interstitial fluid?
Definition
High
Term
What is the relative concentration of Ca2+ in the intra-cellular?
Definition
High (In membranous organelles)
Term
Are proteins present in the blood plasma?
Definition
Yes
Term
Are proteins present in the interstitial fluid?
Definition
No
Term
Are proteins present in the intra-cellular fluid?
Definition
Yes
Term
Are phosphates present in the blood plasma?
Definition
No
Term
Are phosphates present in the interstitial fluid?
Definition
No
Term
Are phosphates present in the intra-cellular fluid?
Definition
Yes
Term
What is the osmolarity of the extra-cellular and intra-cellular fluid?
Definition
300mOsM
Term
What percentage of the body if extra-cellular fluid?
Definition
33%
Term
What percentage of the body if intra-cellular fluid?
Definition
67%
Term
Due to the variation in concentration of aqueous ions, the fluids of the body are said to be in a what?
Definition
Chemical disequilibrium
Term
What maintains the chemical disequilibrium of the ECF and ICF?
Definition
The use of active transport AND physical barriers such as membranes
Term
As the solutions of ECF and ICF are isosmotic they are are said to be in a what?
Definition
Osmotic equilibirum
Term
How does the body counteract the alterations of its chemical disequilibrium?
Definition
By altering the osmotic equilibrium
Term
Which molecules is the lipid bilayer permeable to?
Definition
Lipid soluble, water, small uncharged
Term
Which molecules is the lipid bilayer impermeable to?
Definition
H+, Na+, K+, Ca2+, sugars and amino acids
Term
What are the two types of membrane transport proteins?
Definition
Carrier proteins AND Channel proteins
Term
How do carrier proteins work?
Definition
Substance enters one side, a conformational change occurs, the substrate is then released on the opposite side
Term
How do channel proteins work?
Definition
Contain a channel/pore that allows the diffuson of certain molecules
Term
What is passive transport?
Definition
Movement of molecules that doesn't require energy
Term
What are the two types of passive transport?
Definition
Diffusion AND Facilitated diffusion
Term
What is diffusion?
Definition
Movement of molecules from an area of high concentration to an area of low concentration
Term
What is facilitated diffusion?
Definition
Movement of molecules from an area of high concentration to an area of low concentration using a transport protein
Term
What is a uniporter?
Definition
A carrier protein that transports only one type of molecule
Term
A GLUT transporter transports which molecule/s?
Definition
Glucose
Term
A GLUT transporter is an example of which type of carrier protein?
Definition
Uniporter
Term
What is active transport?
Definition
Movement of molecules from an area of low concentration to an area of high concentration using ATP as an energy source
Term
What are the two types of active transport?
Definition
Primary active transport AND Secondary active transport
Term
What is primary active transport?
Definition
Movement of a molecule from an area of low concentration to an area of high concentration driven by the direct hydrolysis of ATP from ATPases
Term
What is secondary active transport?
Definition
Movement of molecules from an area of low concentration to an area of low concentration coupled with the driving force of a molecule moving from an area of high concentration to an area of low concentration
Term
What does the Na+/K+/ATPase pump do?
Definition
Hydrolyses ATP to ADP and in turn pumps 3Na+ out of the cell for every 2k+ in
Term
Why does the Na+/K+/ATPase pump pump Na+ out?
Definition
So that the high concentration of Na+ outside of the membrane can be used to drive other molecules into the cell by secondary active transport
Term
What is a symport?
Definition
A secondary active transporter that transports both molecules in the same direction
Term
What is an antiport?
Definition
A secondary active transporter that transports both molecules in different directions?
Term
What does the Ca2+/Na+ antiport do?
Definition
Pumps out one Ca2+ ion for one Na+ ion in
Term
What does the Ca2+/ATPase pump do?
Definition
Pumps out one Ca2+ ion for each ATP hydrolysed to ADP
Term
How does glucose enter the intestine cells?
Definition
Using a Na+/Glucose symporter
Term
What is the purpose of the body using both the GLUT uniport and the Na+/Glucose symporter?
Definition
Each has a different affinity for glucose, so the Na+/Glucose symporter can pump glucose into the intestine cell and the GLUT uniport can pump glucose from the intestine cell into the blood
Term
Name two symports?
Definition
Na+/Glucose AND Na+/Amino Acids
Term
Name two antiports?
Definition
Na+/K+/ATPase pump, Na+/Ca2+
Term
Name two uniports?
Definition
GLUT and H+/ATPase (Proton pump)
Supporting users have an ad free experience!