Term
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Definition
Selenium
iodine
chromium
molbdenum
manganese
iron
copper
zinc |
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Term
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Definition
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Term
| The most extensively studied mineral |
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Definition
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Term
| Trace mineral amount (mg/day) |
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Definition
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Term
| Ultra trace mineral amount (mg/day) |
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Definition
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Term
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Definition
| heme (Fe2+/reduced) and non-heme (mostly Fe3+/oxidized) |
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Term
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Definition
Primarily animals foods cept dairy
it is embeded in a porphyrin ring |
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Term
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Definition
plants
enriched foods and supplements
from iron pots while cooking |
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Term
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Definition
meats and seafood
grains and legumes
fruit
vegetables |
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Term
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Definition
| ...... absorbed across the brush border membrane by a heme carrier protein. once inside the heme degrades and the iron is released. |
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Term
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Definition
1. ____ is reduced by HCL in the stomach and enzymes in the duodenum
2. ____ is absorbed through the brush border membrane by DMT1 protein
3. binds to a cytosolic protein and does 1 of 3 things.
a.perform cell function
b. stored as ferritin
c. leaves cell via ferroportin
4. Ferroportin transports ____ out and Hephaestin oxidizes it so it can be transported in the blood via tranferrin. |
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Term
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Definition
oxygen delivery
cofactor
antioxidant |
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Term
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Definition
ferritin
hemosiderin (liver only when ferritin reaches capacity) |
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Term
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Definition
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Term
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Definition
poor diet
poor absorption
blood loss
genetics
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Term
| high risk groups for fe deficiency |
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Definition
| kids up to teens and females |
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Term
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Definition
koilonychia (spoon shaped nails)
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Term
| Early stages without anemia |
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Definition
deficiency where fe iron containing proteins and ferritin are low, but hemoglobin and hematocrit levels are normal. |
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Term
| iron deficiency with anemia |
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Definition
| low hemoglobin, hematocrit, ferritin, iron containing proteins. |
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Term
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Definition
early stages wlo anemia
irondeficiency with anemia
microcytic anemia
low rbc |
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Term
| treatment for fe deficiencies |
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Definition
more heme iron, nonheme iron, vitamin c.
increase consumption of things that enhance absorption. |
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Term
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Definition
acids
MFP (meat, fish, poultry) |
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Term
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Definition
phytate
tannins
polyphenols
calcium |
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Term
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Definition
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Term
| hemochromatosis.....what is it and whats the treatment? |
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Definition
accumulation of iron due to defect in protein that absorbs iron= damage to tissues.
reduce iron intake
phlebotomy
medication to increase urinary excretion of fe. |
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Term
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Definition
cofactor
Matrix metalloprotein
antioxidant
gene expression |
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Term
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Definition
most food groups
meat
dairy
grain
seafood |
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Term
| Zn is absorbed better from...... |
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Definition
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Term
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Definition
1. through the brush border membrane by ZIP4.
2. inside enterocyte, if in excess, binds to metallothionein
3. through basolateral membrane by ZnT1
4. through the body with albumin |
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Term
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Definition
acrodermatitis enteropathica
no name=poor wound healing |
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Term
| Acrodermatitis enteropathica..signs and treatment. |
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Definition
dermatitis
diarrhea
growth failure
pharmacologic zn doses (paracellular absorption=absorption between cells) |
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Term
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Definition
slight aciditiy
amino acids (his, cys with thiols -SH) |
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Term
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Definition
alkalinity
polyphenols and tannins
oxalates
calcium and iron |
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Term
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Definition
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Term
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Definition
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Term
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Definition
cupric/oxidized state (cu2+)
reduced (cu+) |
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Term
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Definition
1. must be reduced.
2. Ctr1 transports reduced ___ into intestinal cells.
3. ATP7A moves cu to blood.
4. albumin transports it in the blood. |
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Term
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Definition
oxidize iron with hepaestin and ceruloplasmin.
cofactor
collagen strength (bone, blood vessel) |
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Term
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Definition
Menkes disease
aka Menkes kinky hair syndrome |
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Term
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Definition
| acrodermatitis enteropathica |
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Term
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Definition
Menkes disease
no name=collagen prob (aortia rupture) |
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Term
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Definition
| cu is trapped in intestinal cells |
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Term
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Definition
| during high levels of ___ATP7B will excrete ___into the bile to be excreted through feces. |
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Term
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Definition
wilsons disease
kayser fleischer rings |
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Term
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Definition
| mutation of ATP7B protein=no transport of __when levels are high=excess |
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Term
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Definition
__ restricted diet
medication=penicillamine=inc urinary excretion of __
zn supplements
mo supplements (inc excretion) |
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