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Toxins
Endo-/Exotoxins
23
Microbiology
Undergraduate 4
01/23/2012

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Term
Exotoxin
Definition
Protein toxin, secreted by bacteria, that kills or damages host cells
Term
1) excreeted by gram-pos
Definition
1) exotoxin
Term
2) heat labile (heat affects the toxicity)
Definition
2) Exotoxins
Term
3) antigenic
Definition
3)exotoxin
Term
4) polypeptides (proteins)
Definition
4) exotoxins
Term
5) highly toxic, no fever
Definition
5) Exotoxin
Term
1)Gram negative
Definition
1) Endotoxins
Term
2) heat stabile
Definition
2) endotoxin
Term
3) non-antigenic/not very antigenic
Definition
3) endotoxins
Term
4) polysaccharides
Definition
4) endotoxin
Term
5) weakly toxic, fever
Definition
5) Endotoxins
Term
cytolytic
Definition
the dissolution or destruction of a cell (dose dependent)
Term
bipartite
Definition
a two part toxin that acts through one another
Term
hemolysins
Definition
lyse red blood cells
Term
leucocidins
Definition
lyse white blood cells
Term
hyaluronidase
Definition
allows spread through connective tissue
Term
coagulase
Definition
coagulates plasma
Term
streptokinase/fibrinolysins
Definition
dissolves plasma
Term
classification of disease producing organisms
Definition
1)extracellular
2)facultative intracellular
3)obligate intracellular
Term
extracellular
Definition
survive out side the cell, susceptible to phagocytosis
Term
facultative intracellular
Definition
not phagocytized easily
Term
obligate intracellular
Definition
require a living cell to grow
Term
Endotoxin
Definition
Lipopolysacchrides in the outer membrane of gram neg. bacteria that become toxic to the host after the cell has lysed
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