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Toxicology
Antidotes
23
Pharmacology
Professional
06/22/2010

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Term
oxygen/O2 is an "antidote"(helps) what
Definition
Antidysrhythmic agent

For almost any type of abnormal homeostasis state
Term
What is the MOA of ipecac, syrup of
Definition
Irritates gastric mucosa
Stimulates vomit centers in brain
Term
Loss of gag reflex, caustic ingestion, and ingestion of petroleum products are all Contra Indications of what drug
Definition
ipecac, syrup of
Term
What are some side effects of ipecac
Definition
Vegas nerve stimulation
Bradycardia
hypotension
prolonged vomiting
Term
MOA of Liqui-char
Definition
Inhibits absorption of drugs by binding to and adsorbing them in the GI tract
Term
Side effects of activated charcoal
Definition
Vomiting, Aspiration, diarrhea, and costipation
Term
What is digoxin immune FAB/ Digibind an antidote for
Definition
Digoxin OD
Digoxin toxicity with hyperkalemia, arrhythmias, CHF, or shock
Term
Severe sinus bradycardia, heart blocks , and blurry or snowy vision or yellow/greening of vision are all signs of what
Definition
digoxin OD or Toxicity
Term
acetylcysteine/ Mucomyst is an antidote for what
Definition
acetaminophen/ Tylenol OD

Mucolytic
Term
How does acetylcysteine protect the liver from a tylenol OD
Definition
Increases hepatic glutathione
given PO for overdose
Term
Besides being a Antihistamine what is Benadryl antidote for
Definition
reversing dystonic reactions
Antidote for Phenothiazine's
Term
naloxone/ Narcan is indicated for what
Definition
Known or suspected OD c RR <8 or decreased tidal volume
Term
flumazenil/ Romazicon is an antidote for what
Definition
Benzodiazepine OD/ toxicity
Term
pralidoxime chloride/ 2 Pam Chloride is an antidote or Organophosphate poisoning, How?
Definition
Reactivates cholinesterase
Term
amyl nitrate/ Vaporole is a Nitrate but also an antidote for what
Definition
Cyanide poisoning
it forms a nontoxic complex c the cyanide ion to create cyanomethemoglobin( is excreted in liver)
Term
How does sodium bicarbonate work as an antidote
Definition
neutralizes acid by binding with hydrogen ions to form carbonic acid; helps restore normal ph
Decreases precipitation of myoglobin in renal tubules
Term
When is sodium bicarbonate indicated
Definition
Tricyclic anti depressant OD
prolonged cardiac arrest
Metabolic Acidosis
Crushsyndrome >4hrs
Hyperkalemia
Term
calcium chloride/ CaCl2 is an antidote for what
Definition
Black widow bites
Scorpion stings/ restores nerve conduction
calcium channel blocker OD

indicated when suspected hyperkalemia or crush force > 4hrs
Term
calcium gluconate/ Kalcinate is an antidote for what
Definition
Black widow bites
Magnesium sulfate OD
Calcium channel blocker OD
Term
When is potassium chloride indicated
Definition
Tx or prevention of hypokalemia secondary to diuretic or Corticosteroid therapy
Diarrhea
Vomiting
Sever diuresis
Term
What is a contra indication for flumazenil/ Romazican
Definition
A pt in status epilepticus who has been given Benzo's to control his condition
Pt c tricyclic anti depressant OD
Term
The mark I kit contains what 2 drugs
Definition
atropine sulfate- First
pralidoxime chloride/ 2-Pam Chloride- Second
Term
What is the major side effect for Mucomyst
What type of pt would this be bad for
Definition
Bronchospasms
Asthma pt's
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