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Toxicology Chapter 4
Risk Assessment
14
Chemistry
Undergraduate 4
03/24/2010

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Term
Hazard
Definition
Capability of a substance to cause an adverse effect.
Term
Risk
Definition
Probability that the hazard will occur under specific exposure conditions.
Term
Risk Assessment
Definition
The process by which hazard, exposure, and risk are determined.
Term
Risk Management
Definition
The process of weighing policy alternatives and selecting the most appropriate regulatory action based on the result of risk assessment and social, economic, and political concerns.
Term
Risk Objective: B (1)
Definition
Balance Risks and Benefits (Drug and Pesticides)
Term
Risk Objective: S(2)
Definition
Set target level of risk (food contaminants and water pollutants)
Term
Risk Objective: S(3)
Definition
Set priorities of program activities (Regulatory Agencies, Manufacturers, and Environmental and Social Organizations)
Term
Risk Objective: E(4)
Definition
Estimate residual risk and the extent of risk reduction after the steps are taken to reduce risks.
Term
Basic Steps: (1) Exposure Assessment
Definition
Measurement or estimation of the intensity, frequency, and duration of human exposure for agents.
Term
Basic Step: (2) Risk Characterization
Definition
Estimation of the incidence of health effects under the various conditions of human exposure.
Term
Basic Step: (3) Hazard Identification
Definition
Characterization of innate adverse effects of agents
Term
Basic Step: (4) Dose Response Assessment
Definition
Characterization of the relation between doses and incidences of adverse effects in exposed populations.
Term
Toxicokinetics
Definition
The study of the time-dependent processes related to toxicants as they interact with living organisms.
Term
Toxicodynamics
Definition
The process of interaction of chemical substances with target sites and subsequent reactions leading to adverse effects.
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