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Top 300 Drugs - Spring 2014 Set 5
For Philadelphia College of Pharmacy Case
23
Pharmacology
Undergraduate 4
02/11/2014

Additional Pharmacology Flashcards

 


 

Cards

Term
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Definition
BRAND:

CLASS:

INDICATION:

MOA:

DOSAGE FORMS:
Term
Ethinyl Estradiol/Levonorgestrel
Definition
BRAND: Aviane, Alesse

CLASS: Oral contraceptive - monophasic

INDICATION: Contraception

MOA: Supress follicle stimulating hormone (FSH) and luteinizing hormone (LH) to inhib ovulation, cause edematous endometrial changes that are hostile to implantation of the fertilized ovum, and produce degeneration of corpus luteum. Progestings inhib ovulation by suppressing LH, inhib sperm, slow ovum transport, produce thin endometirum to stop implantation, cause cervical mucus to be hostile to sperm.

DOSAGE FORMS: Tablet
Term
Ethinyl Estradiol/Norethindrone
Definition
BRAND: Loestrin 24 FE, Loestrin FE 1/20

CLASS: Oral Contraceptive - monophasic

INDICATION: Contraception

MOA: Supress follicle stimulating hormone (FSH) and luteinizing hormone (LH) to inhib ovulation, cause edematous endometrial changes that are hostile to implantation of the fertilized ovum, and produce degeneration of corpus luteum. Progestings inhib ovulation by suppressing LH, inhib sperm, slow ovum transport, produce thin endometirum to stop implantation, cause cervical mucus to be hostile to sperm.

DOSAGE FORMS: Tab
Term
Ethinyl Estradiol/Norgestrel
Definition
BRAND: Low-Orgestrel, Lo-ovral

CLASS: Oral contraceptive - monophasic

INDICATION: Contraception

MOA: Supress follicle stimulating hormone (FSH) and luteinizing hormone (LH) to inhib ovulation, cause edematous endometrial changes that are hostile to implantation of the fertilized ovum, and produce degeneration of corpus luteum. Progestings inhib ovulation by suppressing LH, inhib sperm, slow ovum transport, produce thin endometirum to stop implantation, cause cervical mucus to be hostile to sperm.

DOSAGE FORMS: Tablet
Term
Ethinyl Estradiol/Desogestrel
Definition
BRAND: Apri, Desogen, Ortho-cept

CLASS: Oral contraceptive - monophasic

INDICATION: Contraception

MOA: Supress follicle stimulating hormone (FSH) and luteinizing hormone (LH) to inhib ovulation, cause edematous endometrial changes that are hostile to implantation of the fertilized ovum, and produce degeneration of corpus luteum. Progestings inhib ovulation by suppressing LH, inhib sperm, slow ovum transport, produce thin endometirum to stop implantation, cause cervical mucus to be hostile to sperm.

DOSAGE FORMS: Tablet
Term
Ethinyl Estradiol/Desogestrel
Definition
BRAND: Kariva, Mircette

CLASS: Oral contraceptive - biphasic

INDICATION: Contraception

MOA: Supress follicle stimulating hormone (FSH) and luteinizing hormone (LH) to inhib ovulation, cause edematous endometrial changes that are hostile to implantation of the fertilized ovum, and produce degeneration of corpus luteum. Progestings inhib ovulation by suppressing LH, inhib sperm, slow ovum transport, produce thin endometirum to stop implantation, cause cervical mucus to be hostile to sperm.

DOSAGE FORMS: Tablet
Term
Ethinyl Estradiol/Drospirenone
Definition
BRAND: Ocella, Yasmin

CLASS: Oral contraceptive - monophasic

INDICATION: Contraception

MOA: Supress follicle stimulating hormone (FSH) and luteinizing hormone (LH) to inhib ovulation, cause edematous endometrial changes that are hostile to implantation of the fertilized ovum, and produce degeneration of corpus luteum. Progestings inhib ovulation by suppressing LH, inhib sperm, slow ovum transport, produce thin endometirum to stop implantation, cause cervical mucus to be hostile to sperm.

DOSAGE FORMS: Tablet
Term
Ethinyl Estradiol/Drospirenone
Definition
BRAND: Yaz, Gianvi

CLASS: Oral contraceptive - monophasic

INDICATION: Contraception

MOA: Supress follicle stimulating hormone (FSH) and luteinizing hormone (LH) to inhib ovulation, cause edematous endometrial changes that are hostile to implantation of the fertilized ovum, and produce degeneration of corpus luteum. Progestings inhib ovulation by suppressing LH, inhib sperm, slow ovum transport, produce thin endometirum to stop implantation, cause cervical mucus to be hostile to sperm.

DOSAGE FORMS: Tablet
Term
Estradiol Transdermal Patch
Definition
BRAND: Vivelle-DOT, Estraderm

CLASS: Estrogen

INDICATION: Abnormal vasomotor function/atrophic vagina or vulva/Menopause, Postmenopausal osteoporosis (prophylaxis)

MOA: Potent natural estrogen cause proliferation of vaginal and uterine mucosa, increase calcium deposition in bone, and accelerate ephiphyseal closure after initial growth stim

DOSAGE FORMS: Transdermal patch
Term
Ethinyl estradiol and etonorgestrel ring
Definition
BRAND: Nuvaring

CLASS: Conctraceptive

INDICATION: Contraception

MOA: Supress follicle stimulating hormone (FSH) and luteinizing hormone (LH) to inhib ovulation, cause edematous endometrial changes that are hostile to implantation of the fertilized ovum, and produce degeneration of corpus luteum. Progestings inhib ovulation by suppressing LH, inhib sperm, slow ovum transport, produce thin endometirum to stop implantation, cause cervical mucus to be hostile to sperm.

DOSAGE FORMS: Vaginal ring
Term
Ethinyl Estradiol/Noregestimate
Definition
BRAND: Ortho tri-cyclen lo

CLASS: Oral contraceptive - triphasic

INDICATION: Contraception

MOA: Supress follicle stimulating hormone (FSH) and luteinizing hormone (LH) to inhib ovulation, cause edematous endometrial changes that are hostile to implantation of the fertilized ovum, and produce degeneration of corpus luteum. Progestings inhib ovulation by suppressing LH, inhib sperm, slow ovum transport, produce thin endometirum to stop implantation, cause cervical mucus to be hostile to sperm.

DOSAGE FORMS: Tablet
Term
Ethinyl Estradiol/Noregestimate
Definition
BRAND: Sprintec, Ortho-Cyclen

CLASS: Oral contraceptive - monophasic

INDICATION: Contraception

MOA: Supress follicle stimulating hormone (FSH) and luteinizing hormone (LH) to inhib ovulation, cause edematous endometrial changes that are hostile to implantation of the fertilized ovum, and produce degeneration of corpus luteum. Progestings inhib ovulation by suppressing LH, inhib sperm, slow ovum transport, produce thin endometirum to stop implantation, cause cervical mucus to be hostile to sperm.

DOSAGE FORMS: Tablet
Term
Ethinyl Estradiol/Noregestimate
Definition
BRAND: TriNessa, Ortho Tri-cyclen

CLASS: Oral contraceptive - Triphasic

INDICATION: Contraception

MOA: Supress follicle stimulating hormone (FSH) and luteinizing hormone (LH) to inhib ovulation, cause edematous endometrial changes that are hostile to implantation of the fertilized ovum, and produce degeneration of corpus luteum. Progestings inhib ovulation by suppressing LH, inhib sperm, slow ovum transport, produce thin endometirum to stop implantation, cause cervical mucus to be hostile to sperm.

DOSAGE FORMS: Tablet
Term
Ethinyl Estradiol/Noregestimate
Definition
BRAND: Tri-Spirintec

CLASS: Oral contraceptive - Triphasic

INDICATION: Contraception

MOA: Supress follicle stimulating hormone (FSH) and luteinizing hormone (LH) to inhib ovulation, cause edematous endometrial changes that are hostile to implantation of the fertilized ovum, and produce degeneration of corpus luteum. Progestings inhib ovulation by suppressing LH, inhib sperm, slow ovum transport, produce thin endometirum to stop implantation, cause cervical mucus to be hostile to sperm.

DOSAGE FORMS: Tablet
Term
Estradiol Oral
Definition
BRAND: Estrace

CLASS: Estrogen

INDICATION: Abnormal vasomotor function/Menopause, Atrophic vagina or vulva/Menopause, Breast cancer (metastatic), Carcinoma of prostate, Decrease estrogen level secondary to hypogonadism, castration/primary ovarian failure, Postmenopausal osteoporosis

MOA: Potent natural estrogen cause proliferation of vaginal and uterine mucosa, increase calcium deposition in bone, and accelerate ephiphyseal closure after initial growth stim

DOSAGE FORMS: Tab
Term
Conjugated estrogens
Definition
BRAND: Premarin

CLASS: Estrogen hormone

INDICATION: Abnormal vasomotor function/Menopause, Atrophy of vagina/vulva, Postmenopausal osteoporosis prophylaxis, Female hypogonadism

MOA: Act through binding to nuclear receptors in estrogen-responsive tissues. Modulate pituitary secretion of gonadotropins, LH and FSH through neg feedback mechanism. Reduce elevated levels of gonadotropins seen in postmenopausal women

DOSAGE FORMS: Tab
Term
Conjugated estrogens and medroxyprogesterone
Definition
BRAND: Prempro, Premphase

CLASS: Estrogen hormone-progestin hormone combo

INDICATION: Abnormal vasomotor function/Menopause, Atrophy of vagina/vulva, Postmenopausal osteoporosis prophylaxis

MOA: Estrogen=Act through binding to nuclear receptors in estrogen-responsive tissues. Modulate pituitary secretion of gonadotropins, LH and FSH through neg feedback mechanism. Reduce elevated levels of gonadotropins seen in postmenopausal women. Medroxyprogesterone=Transforms proliferative into secretory endometrium. No estrogenic activity.

DOSAGE FORMS: Tab
Term
Medroxyprogesterone
Definition
BRAND: Provera

CLASS: Progestin hormone

INDICATION: Abnormal uterine bleeding unrealted to menstruation, Prevention of estrogen endometrial hyperplasia, Secondary physiologic amenorrhea

MOA: Transforms proliferative into secretory endometrium. No estrogenic activity.

DOSAGE FORMS: Tab
Term
Progesterone
Definition
BRAND: Prometrium

CLASS: Progestin hormone

INDICATION: Prevention of estrogen-induced endometrial hyperplasia, Secondary physiologic amenorrhea

MOA: Transforms proliferative endometirum into secondary endometrium. Parenterally administered progesterone inhibits gonadotropin production which prevents follicular maturation and ovulation

DOSAGE FORMS: Capsule
Term
Testosterone
Definition
BRAND: Androgel, Androderm

CLASS: Androgen

INDICATION: Hypogonadism

MOA: Androgen that is responsible for normal growth and development of male sex organs, prostate, seminal vesicles, penis, scrotum, male hair distribution, laryngeal enlargement, vocal cord thickening, musculature

DOSAGE FORMS: Transdermal patch, topical gel, SubQ implants
Term
Levothyroxine
Definition
BRAND: Synthroid

CLASS: Thyroid supplement

INDICATION: Hypothyroidism, Thyroid stim hormone suppression

MOA: Diffuse into cell nucleus and bind to thyroid receptor proteins attached to DNA. Complex activates gene transcription and synthesis of messenger RNA and cytoplasm proteins

DOSAGE FORMS: Tab
Term
Thyroid
Definition
BRAND: Arour thyroid

CLASS: Thyroid supplement

INDICATION: Hypothyroidism

MOA: Naturally derived thyroid replacement containing both levothyroxine and liothyronine. Diffuse into cell nucleus and bind to thyroid receptor proteins attached to DNA. Hormon nuclear receptor complex activated gene transcription and synthesis of messenger RNA and cytoplasmic proteins.

DOSAGE FORMS: Capsule, Tab
Term
Potassium iodide
Definition
BRAND: SSKI

CLASS: Antithyroid agent

INDICATION: Prevention of thyroid dysfunction due to radiation exposure

MOA: Needed for production of thyroid hormones. Inhib release of thyroid hormones via direct effect on thyroid gland and inhib synthesis of thyroid hormones. Blocks or reduces accumulation of radioactive idoine in the thyroid gland.

DOSAGE FORMS: Tab, Oral solution
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