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Top 200 (2/4)
MWU 2010-2011
31
Pharmacology
Graduate
05/18/2011

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Cards

Term
penicillin*
Definition
Pen VK
cidal: inhibits cell wall synthesis
*COCs have reduced effectiveness because enterohepatic recycling is inhibited
Term
amoxicillin*
Definition
Amoxil
cidal: inhibits cell wall synthesis
*COCs have reduced effectiveness because enterohepatic recycling is inhibited
Term
amoxicillin/clavulanate*
Definition
Augmentin
cidal: inhibits cell wall synthesis *and beta lactamases
Term
cephalexin*
Definition
Keflex
cidal: inhibits cell wall synthesis
*UTI indication
*10% of pt with PCN allergy are cross-reactive
Term
cefdinir***
Definition
Omnicef
cidal: inhibits cell wall synthesis
*UTI indication
*10% of pts with PCN allergy have cross-reactivity
*antacids will decrease absorption
Term
levofloxacin**~
Definition
Levaquin
cidal: inhibits topoisomerase
*UTI indication
~tendonitis/rupture
Term
ciprofloxacin*~
Definition
Cipro
cidal: inhibits topoisomerase
*UTI indication
~tendonitis
Term
moxifloxacin~
Definition
Avelox
cidal: inhibit topoisomerase
~tendonitis
Term
azithromycin*
Definition
Zithromax
static: binds to 50S
*CAP dosing: 500mg PO day 1, then 250mg PO days 2-5 or 500mg IV x 2 days then 500mg PO to complete 7-10 days
Term
doxycycline hyclate***
Definition
( )
static: inhibits protein synthesis
*malaria prophylaxis
*off-label use for rosacea
*photosensitivity
Term
sulfamethoxazole/trimethoprim**
Definition
Bactrim
static: inhibits folate synthesis and PABA utilization
*adequate fluid intake to prevent kidney stones
*photosensitivity
Term
valcyclovir
Definition
Valtrex
inhibits DNA polymerase
Term
acyclovir
Definition
Zovirax
inhibits DNA polymerase
Term
oseltamivir*
Definition
Tamiflu
inhibits DNA polymerase
*75mg PO BID x 5 days within 48 hours of symptoms
Term
fluconazole
Definition
Diflucan
inhibits sterol demethylation
Term
glyburide
Definition
Micronase
stimulates beta cell insulin release
Term
glipizide ER
Definition
Glucotrol ER
stimulates beta cell insulin release
Term
metformin*~
Definition
Glucophage
increases insulin sensitivity, decreases gluconeogenesis
*also for PCOS!
~risk of lactic acidosis in renal impairment
Term
rosiglitazone~
Definition
Avandia
increases insulin sensitivity via PPAR gamma
~may exacerbate CHF and increase risk of MI
Term
pioglitazone~
Definition
Actos
increases insulin sensitivity via PPAR gamma activation
~may exacerbate CHF
Term
levothyroxine
Definition
Levothyroxyl
synthetic T3
Term
levothyroxine
Definition
Synthroid
synthetic T4
Term
rabeprazole
Definition
Aciphex
Term
esomeprazole
Definition
nexium
Term
lansoprazole
Definition
prevacid
Term
omeprazole
Definition
prilosec
Term
pantoprazole
Definition
protonix
Term
ranitidine
Definition
Zantac
H2 blocker
Term
alendronate
Definition
Fosamax
Term
risendronate
Definition
Actonel
Term
ibandronate
Definition
Boniva
IV q3mo option
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