Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
|
|
Term
| In what disease can treatment with prednisone mask leukemia? |
|
Definition
|
|
Term
| What happens to PT and PTT with hemophilias? |
|
Definition
PTT prolonged
PT is normal |
|
|
Term
| What are Heinz bodies associated with? |
|
Definition
|
|
Term
| Which leukemia characteristically shows a high WBC count? |
|
Definition
|
|
Term
| What is philadelphia chromosome associated with? |
|
Definition
|
|
Term
| What are Reed-Sternberg cells associated with? |
|
Definition
|
|
Term
| What findings are commonly associated with myelofibrosis? |
|
Definition
| teardrop poilkiocytosis, nucleated RBC, giant platelets |
|
|
Term
|
Definition
| excess variation in shape |
|
|
Term
|
Definition
|
|
Term
| Triad of symptoms associated with multiple myeloma? |
|
Definition
| back pain, anemia, and renal insufficiency |
|
|
Term
|
Definition
FAT RN
Fever
Anemia
Thrombocytopenia
Renal dysfunction
Neurologic abnormalities |
|
|
Term
| Signs of sickle cell disease |
|
Definition
Splenomegaly, Sludging
Infection
Cholelithiasis
Kidney-hematuria
Leg ulcers
Eye changes |
|
|
Term
| Percentage of sickle cell carriers? |
|
Definition
|
|
Term
| What are shistocytes commonly associated with? |
|
Definition
microangiopathic hemolytic anemias
TTP, HUS, DIC |
|
|
Term
| What are Howell-Jolly bodies associated with? |
|
Definition
|
|
Term
| What are target cells associated with? |
|
Definition
| Thalessemia and sickle cell |
|
|
Term
What happens to the following in anemia of chronic disease:
Serum iron
TIBC
Ferriten |
|
Definition
Serum iron: decreases
TIBC: decreases
Ferriten: increases |
|
|
Term
|
Definition
weakness
tiredness
light headed
HA
palpitations |
|
|
Term
|
Definition
pallor
hypotension
tachycardia
smooth tongue
cardiac arrhythmias
jaundice
hepatosplenomegaly |
|
|
Term
|
Definition
|
|
Term
|
Definition
depletion of total body iron
blood loss
inadequate supply
defect in iron absoption |
|
|
Term
| Symptoms of iron deficiency anemia |
|
Definition
easily tired
tachycardia
palpitation
SOB esp with exertion |
|
|
Term
|
Definition
pallor(few signs unless advanced)
progressive mucosal skin changes
dysphagia due to esophogeal webbing (Plummer Vinson Syndrome) |
|
|
Term
| lab findings with iron deficiency anemia |
|
Definition
| hypochromic, microcytic, decreased MCV |
|
|
Term
| What happens to hemoglobbin with iron treatement for Fe deficiency anemia? |
|
Definition
| rises over 1-2 months, becomes replished in 6 months |
|
|
Term
| ADR of parenteral therapy iron tx |
|
Definition
| arthralgia, myalgia, fever, pruritis, lymphadenopathy, local pain, muscle necrosis |
|
|
Term
| #1 factor causing failure to respond to iron therapy |
|
Definition
|
|
Term
| What is the Schilling test for? |
|
Definition
|
|
Term
| Causes for folic acid deficiency |
|
Definition
decreased intake (alcoholics),
malabsorption (rare),
increased utilization (pregnancy),
use of folate antagonists (ie. methotrexate) |
|
|
Term
| Symptoms of folic acid deficiency |
|
Definition
|
|
Term
| signs of folic acid deficiency |
|
Definition
pale
mildly icteric
smooth tongue |
|
|
Term
| In which disease do you find Bence Jones Proteins? |
|
Definition
|
|
Term
| In which disease do you find Bence Jones Proteins? |
|
Definition
|
|
Term
|
Definition
I: 1 lymph node region involved
II: 2 regions on same side of diaphragm
III: 2 or > regions on both sides of the diaphragm
IV: disseminated dz
A=presence of constitutional sx
B=presence of fever, wt loss, night sweats |
|
|
Term
| Where do you find paraprotein formation? |
|
Definition
|
|
Term
| Median age of onset for non-hodgkins lymphoma? |
|
Definition
|
|
Term
|
Definition
Induction
Consolidation
Intensification
Maintenence |
|
|
Term
|
Definition
Inherited thrombocytopenia
aplastic anemia |
|
|
Term
| Where do you find decreased haptoglobin? |
|
Definition
|
|
Term
| What does a positive Coombs test indicate? |
|
Definition
| autoimmune hemolytic anemia |
|
|
Term
|
Definition
| fever, night sweats, fatigue, weight loss |
|
|
Term
| What are the tests for vWD? |
|
Definition
|
|
Term
| What are the tests for vWD? |
|
Definition
|
|
Term
| What is given for a heparin OD? |
|
Definition
|
|
Term
| Where do you find segmented neutrophils? |
|
Definition
|
|
Term
| What are the symptoms for TTP? |
|
Definition
Fever
Anemia
Thrombocytopenia
Renal disease
Neutopenia |
|
|
Term
|
Definition
|
|
Term
| What are GP IIb/IIa receptor inhibitors and what do they do? |
|
Definition
|
|
Term
| What do you use to treat HIT? |
|
Definition
|
|
Term
| What defines a blast crisis? |
|
Definition
|
|
Term
| What % of African-Americans carry sickle cell trait? |
|
Definition
|
|
Term
| What do you not give for TTP and ITP? |
|
Definition
|
|
Term
|
Definition
Protein C
Antithrombin III
Protein S
Factor V Leiden
Prothrombotin mutation
High homocystein level |
|
|
Term
| What is the test for hereditary spherocytosis? |
|
Definition
|
|
Term
| What can excess tea drinking cause? |
|
Definition
Deficiency in iron absorption
(from tannins) |
|
|
Term
| What will be the folate level in folic acid deficiency? |
|
Definition
|
|
Term
| course/prognosis in folic acid deficiency? |
|
Definition
| initally rapid improvement in "sense of well being" with blood correction in 2 months |
|
|
Term
| Risk factors for folic acid deficiency? |
|
Definition
renal dialysis patients
cancer pts or chronic debilitating dx
patients on anticonvulsants, OC, isoniazid, antibiotics, chemotherapeutic agents |
|
|
Term
|
Definition
| Replacement of normal bone marrow by neoplastic cells (AML) |
|
|
Term
| What type of cells do you see with lead poisoning? |
|
Definition
|
|
Term
| which disease is a neoplastic disease of plasma cells? |
|
Definition
|
|
