Term
| What organism cause Lyme Disease |
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Definition
| Borrelia burgdorferi (spirochete) |
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Term
| What is the vector in Lyme Disease |
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Definition
|
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Term
| At what location is Lyme disease common in? |
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Definition
| Temperate regions of North America, Europe, and Asia |
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Term
| Describe disease process of Lyme disease |
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Definition
| Incubation (3-32) -- Early infection -- Stage 1/localized infection -- Stage 2/disseminated infection -- Late Infection -- Stage 3/persistent infection |
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Term
| What happens in Stage 1 of Lyme disease |
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Definition
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Term
| What happens in Stage 2 of Lyme disease |
|
Definition
multiple annular secondary lesions
Malaise, fatigue, fever, chills, headache, lymphadenopathy, hepatitis, neurologic, cardiac, migratory arthritis |
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Term
| What happens in Stage 3 of Lyme disease |
|
Definition
| patients develop intermittent joint pain and swelling |
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Term
| What are the neuro problems that are caused in SLE |
|
Definition
| Meningitis, Encephalitis, Cranial neuritis Radiculoneuritis |
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Term
| What are the CSF findings when pt has lyme Disease |
|
Definition
| 100 WBC (lymphocytes), elevated protein, normal glucose |
|
|
Term
| What is the cardiac relation with Lyme |
|
Definition
| 100 WBC (lymphocytes), elevated protein, normal glucose |
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|
Term
| Diagnosis of lyme disease |
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Definition
|
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Term
| What is Western Blot result of Lyme Disease |
|
Definition
IgM 2 of 3 bands present is a positive test
IgG 5 of 10 bands present is a positive test
IgG 5 of 10 bands present is a positive test
IgG 5 of 10 bands present is a positive test
IgG 5 of 10 bands present is a positive test
IgG 5 of 10 bands present is a positive test |
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Term
| Persistent of lyme disease obeer when |
|
Definition
|
|
Term
| Reasons of persistent symptoms of Lymes disease |
|
Definition
No disease
Improper or inadequate therapy
Permanent tissue damage
Slow resolution/immune aberrancy
Fibromyalgia/deconditioning |
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|
Term
| What causes Human monocytic ehrlichiosis |
|
Definition
|
|
Term
| What is the vector of Human monocytic ehrlichiosis |
|
Definition
| Lone Star tick, Amblyomma americanum |
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Term
| What causes Human granulocytic ehrlichiosis/ Anaplasmosis |
|
Definition
| Anaplasma phagocytophilia |
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Term
| What is the vector for Human granulocytic ehrlichiosis/ Anaplasmosis |
|
Definition
| Deer tick, Ixodes scapularis |
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Term
| Clinical presentation of ehrlichiosis |
|
Definition
Fever, Headache, Myalgias, Malaise 84 98
Anorexia 66 37
Rash 36 2-11
chills or rigors, nausea, vomiting, diarrhea, abd pain, cough SOB, lymphadenopathy, confusion |
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Term
|
Definition
|
|
Term
|
Definition
|
|
Term
|
Definition
malaise, fatigue, anorexia, shaking chills, fever, headache, myalgias, arthralgias, nausea, emesis, abdominal pain, depression, emotional lability;
hemolytic anemia, thrombocytopenia |
|
|
Term
|
Definition
Used to detect Babesiosis tetrads of merozoites, rare but diagnositic; Cross- tetrads of merozoites, rare but diagnositic
resemble ring forms of P. falciparum |
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|
Term
| Cause of Rocky Mountain Spotted Fever |
|
Definition
|
|
Term
| Vector of Rocky Mountain Spotted Fever |
|
Definition
| Dermacentor variabilis, American dog tick, in the eastern 2/3 of the US |
|
|
Term
| Disease process of Rocky Mountain Spotted Fever |
|
Definition
| Feeding (1-2 wks) -- fever, myalgias, and headache -- rash 3-5 days after fever (begins on wrists and ankles, then palms and soles) |
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|
Term
| What are the serology finding of Rocky Mountain Fever |
|
Definition
| normal WBC, Anemia, thrombocytopenia, Hyponatremia (50%), Increased LFTs |
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Term
| Cause of Tick Borne Relapsing Fever |
|
Definition
|
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Term
| Vector of Tick Borne Relapsing Fever |
|
Definition
| soft ticks of genus Ornithodoros |
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|
Term
| Reservoirs of Tick Borne Relapsing Fever |
|
Definition
| Rodents and small animals (chipmunks, squirrels, rabbits ...) |
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|
Term
| How is Tick Borne Relapsing Fever transmitted |
|
Definition
| at night, painless bite, feeding in 5-20 minutes |
|
|
Term
|
Definition
| high fevers with rigors, severe headache, myalgias, arthralgias, lethargy, photophobia, and cough |
|
|
Term
|
Definition
| conjunctival suffusion, petechiae, and diffuse abdominal tenderness |
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|
Term
|
Definition
| Bite -- Primary febrile episode (3-6 days) -- fever and symptoms recur after 7-10 days (relapse) |
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Term
| How are relapse of TBRF caused |
|
Definition
spontaneous appearance of antigenic variants under pressure from the host immune system
duration and intensity of symptoms decrease with each relapse |
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|
Term
|
Definition
| Spirochetes seen on peripheral smear, but can have antigenic variation and relapse |
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Term
| Clinical presentation of tularemia |
|
Definition
| from ulceroglandular and typhoidal (tick-borne) to oculoglandular, primary pneumonic and oropharyngeal (not tick-borne) |
|
|
Term
|
Definition
| gram negative rod Francisella tularensis |
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|
Term
|
Definition
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Term
| Common location of tularemia |
|
Definition
|
|
Term
| Mode of transmission of tularemia |
|
Definition
| tick bite, direct contact with infected tissues, ingestion of contaminated meat, inhalation of aerosolized organisms, infected animal or insect bites |
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Term
| Result of Ulceroglandular tularemia |
|
Definition
| Enlarged and tender lymphadenopathy, then necrosis |
|
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Term
| Result of Tyhoidal tularemia |
|
Definition
Fever, chills, headache, myalgias, sore throat, anorexia, nausea, vomiting, diarrhea, abdominal pain, and cough
(not assoc with lymphadenopathy) |
|
|
Term
| How are tularemia diagnosed |
|
Definition
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Term
| Reservoirs of Colorado Tick Fever |
|
Definition
| ground squirrels, rabbits and deer |
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|
Term
| Clinical presentation of Colorado Tick Fever |
|
Definition
| fever, chills, photophobia, headache, myalgias. Recurrences in 2-3 days in 50% of cases |
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|
Term
| Describe Colorado Tick Fever |
|
Definition
| acute self-limited febrile illness |
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|
Term
| Diagnosis of Colorado Tick Fever |
|
Definition
| isolation of coltivirus from blood or CSF |
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|
Term
| Serology findings of Colorado Tick Fever |
|
Definition
| CF, neutralizing antibody, IFA |
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|
Term
| Location of Colorado Tick Fever |
|
Definition
|
|
Term
| Location of Tick Paralysis |
|
Definition
| Pacific Northwest and Rocky Mountain states |
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|
Term
|
Definition
| salivary gland neurotoxin due to tick feeding |
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|
Term
| Clinical presentation of Tick paralysis |
|
Definition
| Symmetric weakness of the lower extremities progresses to an ascending; flaccid paralysis over several hours or days; Sensory function usually spared; acute ataxia without muscle weakness |
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Term
| Diagnosis of tick paralysis |
|
Definition
| Nerve conduction velocity and muscle action potentials are decreased; discovery of tick |
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Term
| Cause of Southern Tick-associated Rash Illness (STARI) |
|
Definition
| Amblyomma americanum, Borrelia lonestari |
|
|
Term
| Vector of Southern Tick-associated Rash Illness (STARI) |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Clinical presentation of STARI |
|
Definition
| headache, aching, fatigue, nausea |
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