Term
| What are 75% of T4 and 70% of T3 bound to? |
|
Definition
| thyroxine-binding globulin (TBG) |
|
|
Term
| The rest of T3 and T4 is bound to what? |
|
Definition
|
|
Term
| TSH secretion is regulated by what two things? |
|
Definition
| thyroid hormone in circulation and hypothalamic TRH |
|
|
Term
| What is the preferred test for assessing the functional state of the thyroid? |
|
Definition
|
|
Term
| What test is 90% reliable in discriminating between cystic and solid thyroid nodules? |
|
Definition
|
|
Term
| antibodies are almost always present with what? and usually present with hyperthroidism |
|
Definition
almost always with Hashimoto's thyroiditis
usually with hyperthyroidism |
|
|
Term
| What is the most common hyperthyroid condition? |
|
Definition
|
|
Term
| what is the most common arrhythmia in hyperthyrodism in elderly patients? |
|
Definition
|
|
Term
| symptoms common with monosymptomatic hyperthyrodism with inanition |
|
Definition
| hypermetabolism and weight loss |
|
|
Term
| plummer's nodule or toxic adenoma is characterized by? |
|
Definition
| benign unilateral swelling of thyroid gland |
|
|
Term
| factitious hyperthyroidism is usually seen in whom? |
|
Definition
|
|
Term
| what is the preferred means of diagnosis for hyperthyrodism? |
|
Definition
|
|
Term
| What is serum thyroglobulin used for? |
|
Definition
| track defectiveness of therapy for cancer |
|
|
Term
| What is the MOA of antithyroid drugs |
|
Definition
| Blocks oxidation of iodine |
|
|
Term
| Which antithyroid drug is preferred during pregnancy? |
|
Definition
|
|
Term
| What is a valuable adjunct therapy to relieve symptoms? |
|
Definition
|
|
Term
| Almost all patients with grave's disease and toxic nodular goiter can be rendered euthyroid with what? |
|
Definition
| Radioactive iodine therapy |
|
|
Term
| What is thyroid storm characterized by? |
|
Definition
1) fever
2) severe tachycardia
3) extreme sweating
4) pronounced restlessness
5) leads to dehydration and shock |
|
|
Term
| pituitary hypothyrodism what usually develops first? |
|
Definition
| hypogonadism (impotence or amenorrhea) |
|
|
Term
| subacute thyroiditis is characterized by? |
|
Definition
1) pain in neck, throat, ears
2) fever
3) viral symptoms
4) thyroid enlarged
5) striking elevation of SER |
|
|
Term
| What group of people has the highest incidence of lymphocytic thyroditis |
|
Definition
|
|
Term
| What is the most common cause of goitrous hypothyrodism? |
|
Definition
| autoimmune thyroditis (Hasimoto's thyroditis) |
|
|
Term
| presence of what confirms diagnosis with hasimoto's thyroditis? |
|
Definition
|
|
Term
| What med is used to suppress the goiter in Hashimoto's thyroditis? |
|
Definition
|
|
Term
| What are symptoms usually a result of with nodules, goiters, and cancer? |
|
Definition
| compression of surrounding structures. |
|
|
Term
| What is the most important pathogenesis for thyroid cancer? |
|
Definition
| exposure to radiation as a child |
|
|
Term
| What is the most direct, expeditious, and ultimately cost effective approach to isolated thyroid nodules? |
|
Definition
|
|
Term
| What is the most common abnormality associated with euthyroid sick syndrome? |
|
Definition
|
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