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Thyroid pathophysiology
Lecture 5
6
Pharmacology
Professional
09/23/2012

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Cards

Term
What are the signs and symptoms of hyperthyroidism?
Definition
Goiter
Weight loss, increased appetite
Tachycardia
Splitting of the nails, retracted eye lids
Change in the menstrual cycle
Heat intolerance
Term
What are the signs and symptoms of the thyroid storm?
Definition
fever, dehydration
Delirium
vomiting, diarrhea
Tachycardia, eventual coma
Term
How is hyperthyroidism diagnosed?
Definition
Low TSH, High T4/T3
Term
What are the etiologies behind hyperthyroidism?
Definition
- Grave's Disease - #1 cause, autoimmune. Eyes bulge
- Toxic multinodular goiter - extra nodules in glan
- Toxic ademona - solid nodules
Term
What are the signs and symptoms of hypothyroidism?
Definition
Goiter, slowed activity
Decreased CV, GI, neuromuscular
Dry skin, cold intolerance
Weight gain
Weakness, lethargy, depression
Term
What are the etiologies behind hypothyroidism?
Definition
- Hashimoto's disease - #1, autoimmune destruction of the gland
- Iatrogenic - physician caused
- Iodine deficiency - rarely seen due to salt
- Pituitary disease - low TSH
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