Term
|
Definition
| Alteplase (tPA, Activase) |
|
|
Term
| How is Activase given and why? |
|
Definition
| IV only. Destroyed by GI acids |
|
|
Term
|
Definition
| Dissolves clots by converting plasminogen to plasmin, which can then degrade fibrin in clots. |
|
|
Term
|
Definition
| Dissolve clots in acute M, clear occluded catheters, acute ischemic stroke |
|
|
Term
| Side effects of ALL thrombolytics/Antiplatelets |
|
Definition
| Excessive bleeding from GI tract (stools, urine), gums, nose, intracranial, petechiae, IV sites or wounds or any other site |
|
|
Term
|
Definition
| Life threatening hemorrhage |
|
|
Term
| Contraindications of ALL thrombolytics/anti-platelets |
|
Definition
| Bleeding, peptic ulcer, hypertension, recent hemorrhagic stroke, hypersensitivity. |
|
|
Term
| Nursing implications for activase |
|
Definition
|
|
Term
|
Definition
|
|
Term
| Where is aspirin absorbed? |
|
Definition
|
|
Term
| What is the effect of aspirin |
|
Definition
| Inhibits platelet aggregation to prolong bleeding time |
|
|
Term
|
Definition
| Prophylaxis for MI, TIA, and post-MI |
|
|
Term
|
Definition
| Hypersensitivity, GI upset |
|
|
Term
| Contraindication specific to Aspirin |
|
Definition
|
|
Term
| What do you do when a person OD's on aspirin? |
|
Definition
| GI lavage, correction of acid/base, diuretics and symptom management |
|
|
Term
| Nursing teaching for aspirin |
|
Definition
|
|
