| Term 
 
        | Name 3 Thrombolytic Drugs |  | Definition 
 
        | -Streptokinase -Urokinase
 -Alteplase
 |  | 
        |  | 
        
        | Term 
 
        | What is the mechanism of action of Thrombolytics? |  | Definition 
 
        | They activate the fibrinolytic system. Plasminogen is converted into plasmin which degrades the fibrin networks of a clot. |  | 
        |  | 
        
        | Term 
 
        | What are Thrombolytics used for (4)? |  | Definition 
 
        | -Dissolve existing clots after they have formed -After heart attack to prevent prolonged myocardial ischemia
 -In medical emergencies to treat MI (myocardial infarction), PE (pulmonary embolism), arterial occlusions, and DVT (deep vein thrombosis)
 -To restore potency to occluded central venous catheters
 |  | 
        |  | 
        
        | Term 
 
        | ADRs of Thrombolytics (4) |  | Definition 
 
        | -Bleeding -Hypersensitivity reactions
 -Nausea
 -Vomiting
 |  | 
        |  | 
        
        | Term 
 
        | What are the nursing considerations when administering Thrombolytics (4)? |  | Definition 
 
        | -Contraindications -Cardiac monitoring
 -Monitor vital signs
 -Patient education
 |  | 
        |  | 
        
        | Term 
 
        | Name the antidote to Thrombolytics. |  | Definition 
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