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Things To Know
Review for Bio Exam
193
Biology
Undergraduate 2
02/14/2011

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Cards

Term
What are the 7 characteristics that describes living organisms?
Definition
Order
Response to environment
Growth and development
Reproduction
Evolutionary adaptation
Regulation
Energy processing
Term
What are the themes in Biology?
Definition
Evolution is the ultimate theme of Biology
New properties emerge at each level of the biological hierarchy
Organisms interact with their environments, exchanging energy
Structure and function are correlated
Cells are the basic units of life
The continuity of life is based on DNA
Term
How is a prokaryotic cell different from a eukaryotic cell?
Definition
A prokaryotic cell has no nucleus, a prokaryotic cell is normally smaller, and it doesn't contain membrane-bound organelles.
Term
What is Negative Feedback?
Definition
Negative Feedback is where a change in a state decreases the input
Term
What is Positive Feedback?
Definition
Positive feedback is when a change in a state increases the input
Term
Which feedback system is the most common found in the body?
Definition
Negative
Term
Why is evolution important?
Definition
It's why there's unity and diversity of life
Term
What are the three Domains?
Definition
Bacteria, Archaea, Eukarya
Term
What are the bonds found in water?
Definition
Polar covalent bonds
Term
What are the electronegativities of O, N, C, and H relative to each other?
Definition
O > N > C=H
Term
What are hydrogen bonds?
Definition
Bonds that form when a hydrogen is attracted to a highly electronegative atom
Term
What are the emergent properties of water?
Definition
Cohesive
Moderates temperature
Expands when it freezes
Solvent of life
Term
Why is water cohesive?
Definition
Hydrogen bonding! The hydrogen bonds hold the molecule together
Term
Why does water have a high specific heat?
Definition
Hydrogen bonding! The heat has to break the hydrogen bonds first before the molecules can speed up.
Term
Why does water have a high heat of vaporization?
Definition
Hydrogen bonds! The bonds have to be broken before water can pass to the gas phase.
Term
Why does water expand when it freezes?
Definition
Hydrogen bonding! The hydrogen bonding keeps the water molecules far apart from each other so it takes up more space.
Term
What is the max number of hydrogen bonds a water molecule can form?
Definition
4
Term
Why is water a versatile solvent?
Definition
It's polarity. The water ions bind to the solute's ions and surrounds it.
Term
What is the solvent?
Definition
Dissolving agent
Term
What is the solute?
Definition
The substance that dissolves
Term
What is a solution?
Definition
a solvent and solute
Term
What is an aqueous solution?
Definition
A solution where water is the solvent
Term
What is a hydrophilic substance?
Definition
A substance that has an affinity for water
Term
What is a hydrophobic substance?
Definition
A substance that doesn't have an affinity for water
Term
What is an amphipathic substance?
Definition
A substance that has both hydrophilic and hydrophobic properties
Term
What is hydrophobic exclusion?
Definition
When hydrophobic substances are excluded away from hydrogen-bonded network. Hydrophobic substances pool away together away from water.
Term
What is concentration?
Definition
Measured with molarity, the number of moles per liter of solution
Term
Dissociation of water molecules
Definition
H20 --> H+ + OH-
Term
What is an acid?
Definition
An acid is a substance that increases the [H+] in a solution
Term
What is a base?
Definition
A base is a substance that decreases the [H+] in a solution
Term
Relationship between [H+] and [OH-]?
Definition
[H+][OH-] = 10^-14
Term
What is a neutral solution?
Definition
A neutral solution is where [H+]=[OH-]
Term
What is an acidic solution?
Definition
A solution where [H+]>[OH-]
Term
What is a basic solution?
Definition
A solution where [H+]<[OH-]
Term
How does each unit on a pH scale differ from each other?
Definition
Difference of n equals 10^n difference in acidity or basicity. Example, a pH of 2 and a pH of 4 have two units of difference. So pH 2 is 10^2 (100) times more acidic than ph 4
Term
What is a buffer?
Definition
A buffer is a substance that minimizes the change in pH when it's added to a solution
Term
Hydroxyl Group
Definition
-OH. Is polar and form hydrogen bonds with water.
Term
Carbonyl Group
Definition
-C=O. Found in sugars. A ketone is a carbonyl group between two carbons. An aldehyde is a carbonyl group between a carbon and a hydrogen.
Term
Carboxyl Group
Definition
HO-C=O. Tends to be hydrophilic and has acidic properties
Term
Amino Group
Definition
-NH(can have up to 3 three hydrogens). Acts as a base
Term
Sulfhydryl Group
Definition
-SH or HS-. Cysteine contains this group! Two of these groups form a disulfide bridge which stabilizes protein structure
Term
Phosphate Group
Definition
O
"
O-P-O
|
O
Helps provide the backbone for phospholipids.
Term
Methyl Group
Definition
-CH3. Affects DNA, effects sex hormones
Term
Number of covalent bonds carbon can form?
Definition
4
Term
Diversity of carbon skeleton
Definition
Skeleton can be a straight chain or be branched
Term
What are isomers?
Definition
Molecules with the same formula, but different structures and properties.
Term
What are the 3 types of isomers?
Definition
Structural, geometric, enantiomers
Term
Easiest way to recognize structural isomers?
Definition
Look and see what each carbon is connected to
Term
What are the requirements for geometric isomers?
Definition
Has to have a double bond between two carbons and the two carbons have to be attached to different atoms
Term
What are enantiomers?
Definition
Mirror images
Term
What are enantiomers?
Definition
Mirror images
Term
What is an asymmetric carbon?
Definition
A carbon attached to 4 different groups
Term
What is a hydrocarbon?
Definition
A carbon attached to hydrogens
Term
What is ATP?
Definition
Adenosine triphosphate. It's an important source of energy for cellular processes. It contains a phosphate group, (a max of 3), a sugar, and a nitrogenous base.
Term
Trans vs. Cis
Definition
Trans is when the groups are on different sides of each other, and cis is when the groups are on the same sides as each other.
Term
What are the four classes of biomolecules?
Definition
Carbohydrates
Lipids
Nucleic Acids
Proteins
Term
Polymers vs Monomers
Definition
Monomers are small molecules and polymers are many monomers put together
Term
How are polymers made?
Definition
Dehydration process! A hydrogen from monomer combines with a hydroxyl group of another monomer which binds the molecule together and releases water
Term
How are polymers broken?
Definition
Hydroylsis! You add water which forces the polymers apart
Term
What are the functions of carbohydrates?
Definition
Energy, structure, and communication
Term
What are the monomers of carbohydrates?
Definition
Monosaccharides!
Term
What is the function of monosaccharides?
Definition
Provide energy
Term
What is the common molecular formula for monosaccharides?
Definition
A multiple of CH2O. Contains a carbonyl group
Term
What is a ketose?
Definition
A carbonyl group within a monosaccharide structure
Term
What is an aldose?
Definition
A carbonyl group on the end of a monosaccharide structure
Term
What are glycosidic linkages?
Definition
They are covalent bonds that hold monosaccharides together between carbons 1 and 4.
Term
What are polysaccharides?
Definition
Polysaccharides are hundreds of monosaccharides put together
Term
What are the functions of polysaccharides?
Definition
Structure and support.
Term
What is starch?
Definition
The polysaccharide found in plants that is digestible
Term
What are the two forms of starch?
Definition
Amylose - smaller structure
Amylopectin - more complicated structure, has branched linkages
Term
What is glycogen?
Definition
Polysaccharide found in animals that is highly branched and consists of glucose monomers.
Term
What is cellulose?
Definition
Polysaccharide found in plants that is not digestable
Term
Starch vs Cellulose
Definition
We can digest starch because of the 1-4 alpha linkages of the glucose monomers. Cellulose has beta 1,4 linkages.
Term
What are alpha linkages?
Definition
A linkage between two glucose monomers where the oxygen is directed below
Term
What are beta linkages?
Definition
A bond between two glucose monomers where the oxygen alternates up and down between the glucoses
Term
Why are lipids different from the other biomolecules?
Definition
It doesn't have polymers!
Term
What are the three kinds of lipids?
Definition
Triglycerides
Phospholipids
Steroids
Term
What are the functions of triglycerides?
Definition
Store energy, provide cushioning
Term
How are triglycerols constructed?
Definition
Constructed from a glycerol and 3 fatty acids.
Term
What is an ester linkage?
Definition
The bond between the hydroxyl and carboxyl groups of a glycerol and a fatty acid
Term
What is a saturated fat?
Definition
A fatty acid where all the carbons have the max number of hydrogens bonded to it. All single bonds
Term
What is an unsaturated fat?
Definition
Fatty acid contains at least a double bond. Liquid form
Term
What are hydrogenated oils?
Definition
Unsaturated fatty acids that have had hydrogens added to them
Term
What are completely hydrogenated oils?
Definition
An unsaturated fat that is now saturated
Term
What are partially hydrogenated oils?
Definition
A poly-unsaturated fat that is now just one unsaturated fat
Term
Cis vs trans fat
Definition
CIs is when the groups are on the same side of the carbon chain and trans is when the groups are on different sides of the carbon chain. Cis fats tend to bend and be more solid while trans are more straight and tend to be liquids
Term
What are the functions of phospholipids?
Definition
Provides the structure of cell membranes
Term
What is the structure of phospholipids?
Definition
A glycerol, two fatty acids, and a phosphate group
Term
What is a phospholipid bilayer?
Definition
The structure that surrounds a cell. Has a hydrophilic head and hydrophobic tails
Term
What are the functions of steroids?
Definition
Cell membrane structure, communication
Term
What is the structure of steroids?
Definition
Carbon skeleton of 4 rings. They're different by the groups attached to the skeleton
Term
What is cholesterol?
Definition
The common component of animal cell membranes
Term
Steroids vs Hormones
Definition
All hormones are not steroids. A hormone is defined by its function, not by it's structure
Term
What is the function of enzymatic proteins?
Definition
To speed up chemical reactions
Term
What is the function of structural proteins?
Definition
Provide structural support
Term
What is the function of storage proteins?
Definition
Store amino acids
Term
What is the function of transport proteins?
Definition
Transport materials
Term
What is the function of hormonal proteins?
Definition
Coordinate's the body's activities
Term
What is the function of receptor proteins?
Definition
responds to chemical stimuli
Term
What is the function of contractile and motor proteins?
Definition
movement
Term
What is the function of defensive proteins?
Definition
Fight disease
Term
What are the monomers of proteins?
Definition
Amino acids!
Term
What are the 3 kinds of amino acids?
Definition
Polar and charged, polar and uncharged, and nonpolar
Term
What is the structure of a generic amino acid?
Definition
R
"
amino group - C - carboxyl group
It has just two carbons!!!
Term
Which amino acids falls into the polar and charged category?
Definition
(the acids and bases)

Aspartic Acid
Glutamic Acid
Histidine
Arginine
Lysin
Term
Which amino acids falls into the polar and uncharged category?
Definition
Serine
Threonine
Asparagine
Glutamine
Histine
Tyrosine
Term
Which amino acids falls into the nonpolar category?
Definition
Tryptophan
Glycine
Alanine
Valine
Leucine
Isoleucine
Methionine
Phenylalanine
Proline
Term
How are proteins formed?
Definition
Peptide bonds (by dehydration)! The polypeptide has an N-terminus and C-terminus ends (amino and carboxyl ends).
Term
Polypeptides vs Proteins
Definition
Polypeptides are just a sequence of amino acids. Proteins are amino acids that fold into a specific functional structure
Term
What are the four levels of protein structure?
Definition
Primary
Secondary
Tertiary
Quaternary
Term
What is primary structure?
Definition
The sequence of amino acids. Due to peptide bonds
Term
What is secondary structure?
Definition
The folding and coiling of amino acids. Due to hydrogen bonding between parts of the backbone
Term
What is tertiary structure?
Definition
The 3D organization of the protein. Forms due to the interactions of the side chains (R's). Contains covalent (disulfide bridge), ionic (backbone), hydrogen, and van der Waals bonding (hydrophobic exclusion)
Term
What are the two kinds of secondary structure?
Definition
Alpha helix, beta pleated sheet
Term
What is quaternary structure?
Definition
The overall protein structure from the interaction of multiple polypeptides. Contains covalent, hydrogen, van der Waals (hydrophobic exclusion), and ionic bonding
Term
Which structures are seen in all proteins?
Definition
Primary, secondary, and tertiary
Term
What's the backbone sequence of proteins?
Definition
N-C-C-N and so on
(amino, carbon, carboxyl group)
Term
Does protein function depend on structure or vice versa?
Definition
Function depends on structure because the protein structure spontaneously folds
Term
What is denaturation and what can cause it?
Definition
The unraveling of a protein. Temp changes, pH change, and salt changes can cause it. The proteins are then useless pretty much
Term
What are chaperonins?
Definition
Chaperonins are structures that allows a peptide to hibernate inside it so it can fold and become a protein
Term
What are nucleic acids?
Definition
DNA and RNA I guess
Term
What are the types of nucleic acids?
Definition
DNA and RNA
Term
What are the 3 types of of RNA?
Definition
Messenger RNA (mRNA)
Ribosomal RNA (rRNA)
Transfer RNA (tRNA)
Term
What the functions of nucleic acids?
Definition
Store, transfer and help express genetic info
Term
What are the monomers of nucleic acids?
Definition
Nucleotides
Term
What is the structure of a nucleotide?
Definition
A pentose sugar, a phosphate group, and a nitrogenous base. phosphate group on 5' carbon from the base on 1' carbon from the sugar
Term
What is a nucleoside?
Definition
The pentose sugar plus the nitrogenous base
Term
Up to how many phosphate groups can a nucleotide have?
Definition
3
Term
Pyrimidines vs Purines
Definition
Pyrimidines have 1 nitrogenous ring, purines have 2
Term
Which of the 5 bases belong to the pyrimidines?
Definition
Cytosine, Uracil, Thymine (CUT)
Term
Which of the 5 bases belong to the purines?
Definition
Guanine and Adinine (GA!!!)
Term
Which bases belong to DNA?
Definition
A, G, C, and T
Adinine, Guanine, Cytosine, and Thymine
Term
Which bases belong to DNA?
Definition
A, G, U, C
Adinine, Guanine, Uracil, and Cytosine
Term
Numbering in the sugar vs in the base
Definition
Numbering of carbons in the sugar is with a prime.
Term
How are the RNA and DNA sugar groups different?
Definition
The RNA sugars have a hydroxyl group on the 2' carbon on the sugar, DNA just has oxygen
Term
How are nucleotides joined?
Definition
Phosphodiester linkages! Between the hydroxyl group on 3' carbon and the phosphate group on the 5' carbon
Term
What is the nucleotide backbone?
Definition
It has a sugar-phosphate backbone with a 5' end and a 3' end
Term
Characteristics of nucleotide polymers
Definition
Polar, has a sugar-phosphate backbone, and nitrogenous base appendages, and a nucleotide sequence
Term
DNA structure
Definition
Anti-pararrel(goes in opposite directions), sugar-phosphate backbone, nitrogenous bases, complementary base pairs
Term
RNA structure
Definition
single stranded
Term
Complementary base pairs in DNA
Definition
A - T Adinine - Thymine
G - C Guanine - Cytosine
Term
What are the common features of cells?
Definition
Plasma membrane
Cytoplasm and cytosol
DNA
Ribosomes
Has to obtain energy
Small
Term
What is the size of the cell set by?
Definition
Surface area to volume ratio. Surface area has to be bigger than volume
Term
What are the 2 different ways to study cells?
Definition
Light microscopes and electron microscopes.
Term
Which which kind of electron microscope allows you to see the surface of a cell?
Definition
Scanning
Term
Which kind of electron microscope allows you to see details inside of a cell?
Definition
Transmission electron microscope
Term
What can you do to a cell when you're studying it under a light microscope to make it more detailed?
Definition
Stain it or add contrast. To stain it the cell has to be dead
Term
What is cell fractionation?
Definition
Separating cell contents by continuously spinning it in a centrifuge. In an already spun test tube, the bottom matter is called the pellet, and the top more liquidy matter is the supernatant.
Term
What are the two types of cells?
Definition
Prokaryotic and Eukaryotic
Term
What does the cell wall in a prokaryotic cell do?
Definition
Maintains shape and protects the cell. It also prevents bursting
Term
What is a capsule in a prokaryotic cell?
Definition
It's a substance that covers the cell wall and is made of peptidoglycan, a sugar and a protein. The sugar is sticky which helps it stick to other surfaces
Term
What are the two interchangeable names for the hair-like appendages that are on the surface of prokaryotes?
Definition
fimbraie and pili
Term
What are taxis?
Definition
Deliberate movements of prokaryotes away or to a stimulus.
Term
What is positive chemotaxis and phototaxis?
Definition
Movement towards a chemical stimulus or towards a light stimulus.
Term
What is negative chemotaxis and phototaxis?
Definition
Movement away from a chemical stimulus or away from a light stimulus
Term
What do the prokaryotes use to move?
Definition
Flagella!!
Term
What does the internal structure of a prokaryote look like?
Definition
It lacks complex compartmentalization but has specialized membranes
Term
How is the genomic organization of prokaryotes compare to eukaryotes?
Definition
It has a circular chromosome and it contains much less DNA
Term
Eukaryotic cell compared to a prokaryotic cell
Definition
Larger
Has a true nucleus
Membrane-bound organelles
Elaborate cytoskeleton
Term
What are the two main types of eukaryotic cells?
Definition
Animal and plant
Term
What is the cytoskeleton in a eukaryotic cell good for?
Definition
Movement and cell shape
Term
What is the cytoplasm?
Definition
The area between the nucleus and plasma membrane.
Term
What takes place in the mitochondria?
Definition
Cellular respiration
Term
Where does DNA information processing take place in a eukaryotic cell?
Definition
The nucleus and ribosomes
Term
What does ribosomes make from instructions from DNA?
Definition
proteins
Term
What are the two places DNA is found?
Definition
Nucleus and mitochondria
Term
What is the nuclear envelope?
Definition
A double membrane structure that surrounds the nucleus and separates it from the cytoplasm. It has pores on it.
Term
What do the pores on the nuclear envelope do?
Definition
It regulates what enters and exits
Term
What is the nuclear lamina?
Definition
A substance that lines the side closer to the DNA in the envelope. It help maintains the nucleus' shape
Term
Are the chromosomes in eukaryotic cells linear or circular?
Definition
Linear
Term
What is located inside chromosomes?
Definition
DNA and some protein which if you put them together is chromatin
Term
What is the nucleolus?
Definition
Part of the nucleus where ribosomal subunits are made and rRNA is made
Term
What is a ribosome?
Definition
A particle that is made up of rRNA and protein
Term
What do ribosomes do?
Definition
They make proteins based on the instructions from DNA
Term
Are ribosomes organelles?
Definition
No because they do not have cell membranes
Term
What are the two types of ribosomes?
Definition
Free ribosomes and bound ribosomes
Term
What is the one difference of free and bound ribosomes?
Definition
The only difference is where they are located. The free ribosomes are in the cytosol and the bound ribosomes are attached to the endoplasmic reticulum (ER). Otherwise they are the same and they can switch between roles
Term
What are the organelles located in the endomembrane system? ie: What do the bound ribosomes make?
Definition
Endoplastic reticulum (ER) Golgi apparatus Lysosomes Vacuoles
Term
What are the organelles not located in the endomembrane system? ie: What do the free ribosomes make?
Definition
Mitochondria
Chloroplasts
Peroxisomes
Nucleus
Term
How do ribosomes in eukaryotic cells compare to those in prokaryotic cells?
Definition
They're larger and called 80s ribosomes. The prokaryotic cells are called 70s ribosomes.
Term
What is the difference between smooth ER and rough ER?
Definition
Smooth has no ribosomes on it and rough does (duh)
Term
What are vesicles?
Definition
Sacs made of membrane
Term
What are the functions of the endomembrane system (EMS)?
Definition
Regulates protein traffic (drug trafficking) and metabolic functions
Term
How are the membranes of the EMS related?
Definition
Either through direct physical continuity or by the connection through vesicles. However, each membrane has its own structure and function
Term
What is the endoplasmic reticulum (ER)?
Definition
An extensive network of membranes
Term
What are the functions of smooth ER?
Definition
Synthesis of lipids
Carbohydrate metabolism
Calcium storage (rigor mortis example)
Detoxification
Term
What are the functions of rough ER?
Definition
Protein synthesis
Glycoprotein synthesis
Membrane production
Term
What is the golgi apparatus?
Definition
The cell's receiving and shipping center (post office)
Term
What are the functions of the Golgi Apparatus?
Definition
It still behaves like a post office so just a like a post office would do to mail, the GA modifies, stores, and ships products of the rough ER. It also makes and ships macromolecules.
Term
What is the Golgi Apparatus made out of?
Definition
Cisternae (flattened membranous sacs)
Term
What is the formula and charge for a hydronium ion?
Definition
H3O+
Can also be labeled as H+
Term
What is the formula and charge for a hydroxide ion?
Definition
OH-
Term
Which amino acids falls into the special category?
Definition
Cysteine
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