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Therapeutics Womens/Mens Lynch
Exam 2 Infertility
13
Archaeology
9th Grade
11/23/2010

Additional Archaeology Flashcards

 


 

Cards

Term
Oligomenorrhea
Definition
  • Interval between vaginal bleeding > 35 days
  • Patient typically ovulates, but less often than is typical
  • Weak predictor of infertility
Term
Amenorrhea
Definition
  • Interval between vaginal bleeding > 6 months
  • Patient may only rarely ovulate
  • Strong predictor of infertility
Term
Clinical Indications for IVF
Definition
  • Endometriosis
  • Low sperm counts or motility
  • Structural problems with the uterus or fallopian tubes
  • Antibodies to sperm or eggs
  • The inability of sperm to penetrate or survive in the cervical mucus
  • An unexplained fertility problem
Term
Clomiphene Citrate
Definition
  • Causes antiestrogenic effect @ hypothalamus: stimulates FSH and LH production
  • Initiate treatment on day 3-5 post spontaneous or MPA-induced withdrawal bleed -- this makes sure they are not pregnancy
  • Increase dose by 50 mg per cycle if ovulation does not occur
  • Makes women crazy (highly sexual, emotional) due to fluctuations in estrogen
Term
Predictors of failure with Clomiphene Citrate treatment alone
Definition
  • Obesity
  • Amenorrhea prior to treatment
  • Increased ovarian volume
  • Hyperandrogenemia
  • Older age (weak predictor)
Term
Endometriosis Treatment
Definition

Prevention and Treatment of Symptoms

  • NSAIDs (big doses)
  • Oral contraceptives
  • GnRH antagonists
  • Gonadotropic inhibitor (Danazol)

Treatment of Endometriosis Infertility

  • Surgery
  • No drug therapy will treat endometriosis-induced infertility
Term
Infertile Vs Sterile
Definition

Infertile

Unsuccessful in becoming pregnant after a prolonged period (usually a year) of determined attempts of heterosexual intercourse without contraception

 

Sterile

Incapable of producing offspring

Term
Urine LH Prediction Methods give approximately how long of a fertility window?
Definition
~36 hours
Term
WHO Classification of Anovulation: WHO 1
Definition
Decreased FSH and E2 Levels
Term
WHO Classification of Anovulation: WHO 2
Definition
Normal FSH and E2 Levels
Term
WHO Classification of Anovulation: WHO 3
Definition
Increased FSH, Decreased E2
Term
WHO 2 Treatment Algorithm for Anovulation
Definition

Clomiphene Citrate (CC)

Gonadotropins: FSH + CC

In vitro Fertilization + CC, + FSH

 

Metformin should be considered if CC fails, Metformin should be used in pts with signs and symptom of PCOS

Term
Common Locations of Endometriosis
Definition
  • Ovaries
  • Fallopian Tubes
  • Outer Surface of Uterus
  • Uterine Ligaments
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