Term
| Risk Factors for Pancreatic Cancer |
|
Definition
- Older age (> 50 yo)
- Smoking
- Chronic pancreatitis
- Diabetes
- Alcoholism
- High fat diet
- Occupational exposure to petroleum, DDT
- Obesity and inactivity
|
|
|
Term
| Signs/Symptoms of Pancreatic Cancer |
|
Definition
- Can be asymptomatic
- Pain
- Painless jaundice
- Glucose intolerance
- Weight loss
- GI bleeding
- Steatorrhea
- Pruritis of palms and soles
- Diabetes
- Cachexia
- Hepatomegaly
- Epigastric mass
|
|
|
Term
| Treatment of Resectable Pancreatic Tumors |
|
Definition
- Radical pancreatic resection
- Adjuvant radiation with 5-FU
|
|
|
Term
| Treatment of Unresectable Locally Advanced Pancreatic Tumors |
|
Definition
Standard -- Fluorouracil + XRT
OR
Gemcitabine +/- Erlotinib
Palliative surgical biliary or gastric bypass, radiologic or endoscopic biliary stent placement
Pain relief |
|
|
Term
| Treatment of Unresectable Metastatic Pancreatic Tumors |
|
Definition
Standard
- Palliative surgical biliary or gastric bypass, biliary stent placement
- Pain relief (including nerve blocks or XRT)
- Gemcitabine +/- Erlotinib
|
|
|
Term
| Supportive Care for Pancreatic Cancer |
|
Definition
- Pain management
- Pancreatic Enzymes
- Diet -- small meals and snacks, low in fat, high in carbs, supplements
|
|
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