Term
POXviridae
morphology
clinical
misc |
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Definition
complex coat
DS linear DNA
only DNA virus to replicate in cytoplasm
Smallpox: skin lesions and death
Molluscum contagiosum: small white bumps with central dimple, often found in genital region
No animal reservoirs
Codes for DNA and RNA polymerase
deep hard lesions w/ central depression |
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Term
PAPOVAvirus
morphology
clinical
misc |
|
Definition
naked icosahedral
DS circular DNA
replicates in nucleus
HPV: causes warts
-common warts
-genital warts (condyloma)
-laryngeal warts
-cervical cancer (types 16 & 18)
BK Polyomavirus: mild or asymptomatic infxn in children
JC Polyomavirus: progressive multifocal leukoencephalopathy, degenerative CNS white matter disease
HPV induces koilocytic cells: enlarged nucleus, intracytoplasmic halo |
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Term
ADENOviridae
morphology
clinical |
|
Definition
naked icosohedral
DS linear DNA
Replicates in nucleus
childhood URT infxns
-rhinitis, sore throat, fever, conjunctivitis
Epidemic keratoconjunctivitis (Pink Eye) |
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Term
PARVOviridae, strain B-19
morphology
clinical |
|
Definition
naked icosahedral
only SS linear DNA virus (-)
replicates in nucleus
Erythema infectiosum (fifth disease): affects kids ages 4-12
-fever, "slapped cheek" rash
Transient aplastic anemia crisis: occurs which Parvo virus stops the production of RBC in BM |
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