Term
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Definition
-process and store nutrients
-secrete bile salts
-secrete bilrubin (bile pigment)
-Synthesis of most plasma proteins (clotting)
-Detoxify druge, alcohol, and other toxins
-Elimate waste and toxins |
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Term
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Definition
| liver cells (hepatocytes) |
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Term
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Definition
bile salts
bilirubin
cholesterol |
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Term
| where is bile stored until needed? |
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Definition
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Term
| What organs are in the biliary system? |
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Definition
| liver, gall bladder, associated ducts |
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Term
| What is the job of the common bile duct? |
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Definition
| transports bile from liver and or gall bladder to duodenum |
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Term
| What can the components of bile form? |
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Definition
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Term
| How do bile salts aid lipid digestion? |
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Definition
| since lipases can only act on molecules near the surface of fat droplets, bile sals increase surface area of those droplets by breaking it into several smaller ones. =Emulsifaction |
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Term
| What does increased surfaec area for lipases do? |
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Definition
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Term
| Do bile salts chemically digest lipids? |
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Definition
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Term
| What are bile salts synthesized from? |
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Definition
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Term
| What is an amphipathic molecule? |
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Definition
| has both hydrophillica and hydrophobic regions |
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Term
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Definition
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Term
| How are bile salts secreted? |
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Definition
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Term
| hydrophillic regions of bile- |
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Definition
| prevent lipid droplets from reforming into large droplets |
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Term
| Where are most bile salts reabsorbed? Where are they returned to? |
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Definition
| lower small intestine (ileum). Returned to liver to be re-screted into bile |
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Term
| What is enterohepatic circulation of bile salts? |
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Definition
| bile salt makes several trips through bile, and is eventually eliminated in feces |
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Term
| What is bilirubin (bile pigment)? |
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Definition
results from the breakdown of hemoglobin.
Average red blood cell life=120 days until degraded by immune cells. Heme can be toxic at high levels and is eliminated from body in the form of bilirubin (green/yellow color) |
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Term
| in hepatocytes what is bilirubin attached to? secreted into? |
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Definition
| glucuronic acid, small intestine |
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Term
| What happens to bilirubin in the small intestine? |
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Definition
| it is metabolized by intestinal bacteria- now a brown color, giving feces its brown color. |
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Term
| Most Bilirubin is excreted from body in |
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Definition
| feces- removing the toxic levels |
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Term
| Some bilirubin is absorbed by small instenine and travels in blood to |
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Definition
| be excreted by kidneys, giving urine its yellow color |
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Term
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Definition
| Accumulation of bilirubin in body tissues. Gives skin and eyes yellow color |
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Term
| Newborns have normal jaundice which is: |
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Definition
| live enzyme hat attaches to glucuronic acid to bilirubin is not fully functional until several days of age, turing newborns yellow, but they are more resistant to toxic effects of heme/bilirubin. |
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Term
| Bile can't be secreted without |
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Definition
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