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The Heart
Conduction System and EKG
17
Physiology
Undergraduate 2
09/20/2010

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Term
actin and myosin form a ____________ ____________ that faciliate a transmission of electrical impulses in all directions.
Definition
branching network
Term
intercalcated discs
Definition
irregular, transverse thickenings of plasma membrane that lie between the muscle cells
Term
Intercalated discs contain
Definition
gap junctions and desmosomes
Term
desmosomes
Definition
hold adjacent cells together
Term
gap junctions
Definition
small channels, which allow electrical impulses to pass quickly from one cell to the next

they allow action potentials to spread rapidly throughout heart muscle
Term
first event of cardiac muscle excitation is
Definition
depolarization of SA node
Term
Explain how the atria have time to empty before the ventricles contract
Definition
the prescence of poorly conducting tissue at the AV border slows the heart excitation down by .1 sec
Term
Explain how the atria have time to empty before the ventricles contract
Definition
the prescence of poorly conducting tissue at the AV border slows the heart excitation down by .1 sec
Term
The bundle of his transmits the action potential to
Definition
both ventricles, the lower part contracting first and therefore pushing the blood upwards.
Term
Cardiac muscle action potential is a result of
Definition
depolarization of a muscle or nerve cells
Term
Three major phases of cardiac action potential:
Definition
rapid depolarization, the plateau, and repolarization
Term
Rapid depolarization due to
Definition
Sodium inflow when voltage gated Sodium channels open.
Term
plataeu AKA, due to
Definition
maintained depolarization, calcium inflow when voltage gated slow calcium channels open and potassium outflow when some potassium channels open
Term
repolarization due to
Definition
closure of calcium channels and potassium outflow when additional potassium channels open
Term
refractory period means
absolute v relative
Definition
unresponsive;stubborn
absolute- cell will not respond regardless of stimulus strength
relative-the cell will respond only if the stimulus is “suprathreshold”
Term
How long is the absolute refractory period in heart/skeletal muscle?
Definition
about 250 ms
Term
Intrinsic System- Autorhythmic cells (3)
Definition
initiate Actionpotentials
have unstable resting potentials called( pacemaker potentials)
use calcium influx(as opposed to sodium) for rising action potential
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