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Test 7
Antiviral agents
14
Pharmacology
Graduate
04/20/2010

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Cards

Term
Active antiviral Immunotherapy
Definition
flu shot
flumist-nasal spray with live, weakend virus.
Term
Other antiviral therapies
Definition
H1N1 vaccine
gardasil-Approved for girls and women 9-26 y.o. Prevents cervical cancer and genital warts.
Term
Amantadine, rimantadine
Definition
-Useful against flu A, not B
-prevents the penetration of virus
-there is resistance to this drug
Term
Ribavirin
Definition
-SARS
Term
acyclovir
Definition
-acyclovir
-valacyclovir(valtrex)-2g twice daily for one day
-Indications-HSV-1&2
-Herpes simplex encephalitis
-Chickenpox and shingles
-CMV
-EB
Term
Penciclovir(Denavir)
Definition
Most effective against HSV-1
Term
Docosanol(Abreva)
Definition
-HSV-1
-OTC
Term
Interferon Alpha-2
mode of axn
Definition
-antiviral;Inhibition of RNA translation
-anticancer
-immunoregulatory
-cell growth inhibition
-macrophage activation
-enhancement of lymphocyte activity
-suppression of gene expression
Term
Interferon Alpha-2
Indications
Definition
-Hairy cell leukemia
-Kaposi's sarcoma
-Hep. B and C
-Papillomatosis
-MS
-genital warts
Term
Nucleoside Reverse Transcriptase Inhibitors
Definition
AZT, Didanosine(ddI), Dideoxycytidine(ddC) Lamivudine (3TC), Combivir(3TC with AZT)
Term
Nonnucleoside Reverse Transcriptase Inhibitors
Definition
nevirapine
Term
Protease Inhibitors
Definition
Saquinavir
Indinavir-metallic taste
Term
Raltegravir
Definition
Used when other combination antiretroviral therapy is not working.
Term
Zanamivir and Tamiflu
Definition
-used for flu A, B, and H1N1
-Peramavir-for emergency use only
-Tamiflu-for H5N1 as well
-SE: Neuropyschiatric events and self-injury
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