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Details

ID1 Test 3
Urinary, SSTI, GI, DM Foot, TB
70
Pharmacology
Not Applicable
02/10/2013

Additional Pharmacology Flashcards

 


 

Cards

Term
PREFERRED Treatment of Pyelonephritis
Definition
Ciprofloxacin 500mg BID or 1,000mg ER QD x 7 days
Levofoxacin 750mg QD x 5 days +/- One time dose of IV

> 10% resistance you should give FQs and One time dose of NON-FQ . Give CefTRIAXone or Aminoglycosides
Term
ALTERNATIVE treatment for Pyelonephritis
Definition
Bactrim DS x 7 days with a Ceftriaxone 1g IV single dose or Aminoglycosides
Term
PREFERRED treatment of SEVERE Hospitalization Pyelonephritis AND Healthcare associated pyelonephritis
Definition
FQS - CIpro or Levofloxacin
3rd Generation Cephalosporins EXCEPT for HA-Pyelonephritis
Anti-Pseudomonal Beta-lactam
Pipeacillin/Tazobactam, Ticarcillin/Clavulanate, Ceftazidine, Cefepime
Aztreonam,
Imipenem,Meropenem,Doripenem
+/- Aminoglycosides
Term
PRIMARY Treatment for Pregnant women with UTI
Definition
Beta-Lactams
Term
ALTERNATIVE treatment for Pregnant women with UTI
Definition
Nitrofurantoins and Aminoglycosides
Term
PREFERRED treatment for Prostatitis in males
Definition
FQs and Bactrim
Term
MSSA Treatment
Definition
Anti-Staph BL (Nafcllin, Dicloxacillin Etc.)
BL/BLi Combo
Cephalosporins
Carbapenems (Last Choice)
Term
MRSA Treatment Community Acquired
Definition
Clindamycin
Bactrim
Tetracyclines - Doxycycline and Minocycline
Term
MRSA Nosocomail
Definition
Vancomycin
Linezolid
Daptomycin
Term
Streptococcus Pyogenes
Definition
Penicillin (MOST Reliable)
Clindamycin (99.5%)
Macrolides if Resistance is <10%
Term
Treat Staph and Strept infection
Definition
Clindamycin - Covers both
Bactrim (MRSA) + Beta-Lactam (Strep)
Doxycycline/ Minocycline (MRSA) + Beta-Lactam (Strep)
Vancomycin/ Daptomycin/ Linezolid BOTH
Term
Topical Antimicrobial therapies for Gram +
Definition
Mupirocin, Clindamycin, Erythromycin, CHorhexidine, Benzoyl Peroxide
Term
Empiric Therapy for a Abscess (Aureus)
Definition
Bactrim
Doxycyline/Minocycline
Clindamycin
Term
Empiric Therapy for Nosocomial Abscess
Definition
Vancomycin
Linezolid
Daptomycin
Term
NON-purulent Cellulitis and Erysipelas PREFERRED
Definition
Nafcillin, Oxacillin, Dicloxacillin, Augmentin
Cefazolin, Cephalaexin
Term
NON-purulent Cellulitis and Erysipelas ALTERNATIVE
Definition
Clindamycin
Bactrim + Beta-lactam
Doxycycline/Minocycline + BL
Term
PURULENT Cellulitis and Erysipelas PREFERRED (Severe infection)
Definition
Clindamycin
Bactrim
Doxycycline
Term
PURULENT Cellulitis and Erysipelas NOSOCOMIAL
Definition
Vancoycin
Linezolid
Daptomycin
Term
Clostridial Myonecrosis (Gas Gangrene)
Definition
Penicillin + Clindamycin
Term
Forniers Gangrene
Definition
Piperacilin/Tazobactam (Gram Neg/Pseudomonas Coverage) - Gentamicin (Pseudomonas) - Vancomycin (MRSA), Clindaycin (Anaerobic:Gram+/MRSA) Coverage

SIMPLIFIED : Piperacillin/Tazobactam + Gentamicin + Vancomyin + Clindamycin.

Lots of antibiotics because infection can be caused from GI tract so you have polymicrobial infections normally. Also I want to save my balls so I use 4 antibiotics
Term
Animal Bite AND Humant Bite PREFERRED ORAL
Definition
Augmentin (Amoxicillin/Clav)
Term
Animal Bite AND Human Bite PREFERRED PARENTERAL
Definition
Ampicillin/Sulbactam
Term
Operation, Fever within 48 hours and erythematous changes
Definition
NO Treatment, Not likely to be an infection, not enough time to produce bacteria colonies in body
Term
Operation, Temperature >38.5 w/ Pulse rate >100. Clean wound, trunk, neck extremity
Definition
Start Cefazolin OR Oxacillin OR Clindamycin
Term
Operation, Temperature > 38.5 w/ HR > 100, Wound of perineum or operation on GI tract or female genital tract.
Definition
Cefotetan, FQ, Ampicillin/Sulbactam + Clindamycin

Treating Gram + infection on GI operation because you don't want Gram+ in the normal GI flora.
Term
Agents to use in a CLEAN procedure prophylaxis
Definition
Cefazolin ONE dose prior to surgery PREFERRED
Vancomyin for BL and Allergic patients (If you can't use Cefazolin)
Term
Agents to use in a GI or GU prophylaxis procedure
Definition
Cefotetan, Cefoxitin (only 2nd gens that will cover anaerobes) PREFERRED
Ampicillin/Sulbactam
Ertapenem
BL allergy use Flagyl/Clindamycin + FQS/Aminoglycosides/Aztreonam
Term
Treatment for Nosocomial Diarrhea
Definition
Flagyl 250-500mg QID x 7-10 days
Vancomycin 125-500mg QID x 7-10 days
Term
Bacteria that cause Blood/Mucus stools
Definition
Shigella
Term
Bacteria that Cause Blood in stools
Definition
Campylobacter jejuni
Enterohemorrhagic Coli (SEVERE Bloody diarrhea)
Yersinia Enterocolitica
Term
Bacteria/Viruses that Cause NO Blood/Mucus in stools
Definition
Norwalk
Rotavirus
Term
Shigella
Definition
Septra x 3 days
FQs x 3 Days
Ceftriaxone
Azithromycin
Term
Salmonella NON-Typhus
Definition
Septra 5-7 Days
FQs 5-7 Days
Term
Salmonella TYPHUS
Definition
Cipro OR CefTRIAXone for 10-14 days
Term
Campylobacter
Definition
Cipro 500mg BID x 5 days
Erythromycin 500mg BID x 5 days
Term
E. Coli AND Aeromonas
Definition
Septra x 3 days
Fluoroquinolones x 3 days
Term
Yersinia (SEVERE Infection Only)
Definition
Septra
FQ
Doxycycline
Aminoglycoside
Term
Clostridium Perfringens treatment
Definition
PCN + Clindamycin/Flagyl
Term
Clostridium Botulinum Treatment
Definition
Report to state health department, Use Antitoxin Botulinum
Term
Prophylaxis of Peritonitis
Definition
Cefazolin - Prophylaxis, so your trying to keep Gram + bacteria from getting into the GI tract while you take out the appendix?
Term
Treatments choices for Peritonitis
Definition
Ampicillin/Sulbactam
Carboxypenicillins (Anti-Staph) - Ticarcillin/Clavulanate
Carbapenems - Imipenem, Meropenem
Cephalosporins II, III, IV + Flagyl
FQs + Flagyl
Aminoglycoside + Flagyl/Clindamycin
Term
VRE Treatment
Definition
Quinupristin-Dalfopristin
Daptomycin
Linezolid
Tigecycline
Term
EMPIRIC therapy of Bacterial Meningitis for Infants < 1 month
Definition
Ampicillin + Cefotaxime
Term
EMPIRIC therapy of Bacterial Meningitis for Infants < 2 y/o
Definition
CefTRIAXone + Vancomycin
Term
EMPIRIC therapy of Bacterial Meningitis for Adults
Definition
CefTRIAXone/Cefotaxime + Vancomycin
Term
EMPIRIC therapy of Bacterial Meningitis Adults > 50y/o, Immunocompromised or alcoholics
Definition
Ceftriaxone + Ampicillin + Vancomycin (3 Antibiotics, helps make up for immune deficiency)
Term
Drugs of Choice for N. Meningitidis
Definition
Penicillin Sensitive:
Penicillin 4 mu Q4H
Ampicillin 2gm Q4H
Intermediate/Resistant:
CefTRIAXone 2gm Q12
Cefotaxime 2gm Q6H

All treatment x 7 days
Term
Alternative drugs for N.Meningitidis
Definition
Penicillin Sensitive:
CefTRIAXone 2gmQ12H
Cefotaxime 2gm Q12H
Chloramphenicol 1-1.5gm Q6H
Intermediate Resistance/Resistant
Chloramphenicol 1-1.5gm Q6H
Moxifloxacin 400mg Q24H
Chloramphenicol 1-1.5gm

All treatment x 7 days
Term
Drugs of Choice for S. Pneumoniae Bacterial Meningitidis
Definition
Sensitive Strain: Penicillin
Intermediate Strains: Ceftriaxone 2gm Q12H, Cefotaxime 2gm Q6H
Penicillin Resistant Strain: Ceftriaxone 2gm, Vancomycin 30-60mg/kg/day x Q8H

All treatment x 10-14 days
Term
Alternative drugs for S.Pneumoniae Bacterial meningitidis
Definition
Sensitive Strain
Ceftriaxone 2gm Q12H
Cefotaxime 2gm Q6H
Chloramphenicol 1-1.5gm Q6H
Intermediate:
Meropenem 2gm Q8H
Cefepime 2gm Q8H
Penicillin Resistant Strain
Cefotaxime/Ceftriaxone + Moxifloxacin


All treatment x 10-14 days
Term
Drug of Choice for L. Monocytogenes Bacterial Meningitidis
Definition
Ampicillin 2gm Q4H +/- Gentamicin

Treatment is x 3 weeks
Term
Alternative drugs for L. Monocytogenes Bacterial Meningitids
Definition
Meropenem 2gm Q8H
Bactrim 5mg/kg Q6-12H

Treatments are x 10-14 days
Term
Drugs of choice for S.Agalactiae (GBS) Bacterial Meningitis
Definition
Ampicillin 2gm Q4H +/- Gentamicin (Same as Monocytogenes)

All treatments are 14-21 days (2-3 weeks)
Term
Alternative Drugs for S. Agalactiae (GBS)Bacterial Meningitis
Definition
Ceftriaxone 2gm Q12H
Cefotaxime 2gm Q6H
Chloramphenicol 1-1.5gm Q6H
(Same as Alternative for S. Pneumoniae)

Treatment is 14-21 days (2-3 weeks)
Term
Drugs of Choice H. Influenzae Beta Lactamase NEGATIVE Bacterial Meningitis
Definition
Ampicillin 2gm Q4H

Treatment is x 7 days
Term
Alternative treatment for H. Influenzae Beta Lactamase NEGATIVE Bacterial Meningitis
Definition
Ceftriaxone 2gm Q12H
Cefotaxime 2gm Q6H
Chloramphenicol 1-1.5 gm Q6H
Meropenem 2gm Q8H
Cefepime 2 gm Q8H

All treatment is x 7 days
Term
Drugs of choice for H. Influenzae Beta Lactamase POSITIVE Bacterial Meningitis
Definition
Ceftriaxone 2gm Q12 H
Cefotaxime 2gm Q6H

Treatment is x 7 Days
Term
Alternative Drugs for H. Influenzae Beta Lactamase POSITIVE Bacterial Meningitis
Definition
Chloramphenicol 1-1.5gm Q6H
Meropenem 2gm Q8H
Cefepime 2gm Q8H

Treatment is x 7 days
Term
Drugs of Choice for MSSA Bacterial Meningitis
Definition
Nafcillin 2gm Q4H
Oxacillin 2gm Q4H
(Anti-Staph Penicillins)

Treatment is 14-21 days (2-3 Weeks)
Term
Alternative drugs for MSSA Bacterial Meningitis
Definition
Vancomycin
Meropenem 2gm Q8H
Linezolid 600mg Q12H

Treatment is 14-21 days
Term
Drugs of Choice for MRSA Bacterial Meningitis
Definition
Vancomycin
Oxacillin 2gm Q4H

Treatment is 14-21 days
Term
Alternative drugs for MRSA Bacterial Meningitis
Definition
Linezolid 600mg Q12H
Bactrim 5mg/kg Q6-12H

Treatment is 14-21 Days
Term
Drugs of Choice S.epidermidis Bacterial Meningitis
Definition
Vancomycin

Treatment is 14-21 days
Term
Alternative Drugs of Choice S. epidermidis bacterial meningitis
Definition
Linezolid

Treatment is 14-21 days
Term
Drug of Choice Enterobacteriaceae Bacterial Meningitis
Definition
Ceftriaxone 2gm Q12H
Cefotaxime 2gm Q6H

Treatment is 14-21 days
Term
Alternative drugs of choice Enterobacteriaceae Bacterial meningitis
Definition
Meropenem 2gm Q8H
Cefepime 2gm Q8H
Moxifloxacin 400mg Q24H
Ciprofloxacin 400mg Q8-12H

Treatment is 14-21 Days
Term
Drugs of Choice Pseudomonas Aeruginosa Bacterial Meningitis
Definition
Ceftazidime/Cefepime +/- Tobramycin

Treatment is 14-21 days
Term
Alternative drugs of choice Pseudomonas Aeruginosa Bacterial Meningitis
Definition
Meropenem 2gm Q8H
Cefepime 2gm Q8H
Moxifloxacin 400mg Q24H
Ciprofloxacin Q8-12H

Treatment is 14-21 days
Term
PREFERRED Treatment of Osteomyelitis Contiguous
Definition
Vancomycin +/- Rifampin
Term
ALTERNATIVE Treatment of Osetomyelitis Contiguous
Definition
Linezolid +/- Rifampin(Great bone penetration)

Daptomycin +/- Rifampin (Great bone penetration)
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