Term
| how many different types of antigens are on the surface of a RBC |
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Definition
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Term
| bombay type refering to ABO Blood typing is? |
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Definition
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Term
| the antibody in the plasma related to ABO Blood typing is |
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Definition
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Term
| codominant blood refers to what blood type |
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Definition
| AB blood. No antibodies to either A or B. |
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Term
| homozygous recessive blood type is |
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Definition
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Term
| under certain situations other than IgM this antibody may also be made when considerable transfusions and exposures have occurred |
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Definition
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Term
| Which kind of antibody can cross the placenta |
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Definition
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Term
| What type of reaction occurs with incorrect matching of blood and a blood transfusion |
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Definition
| Antibody-mediated cytotoxic (Type II) Hypersensitivity reaction |
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Term
| The antibodies of the patient may attack the blood being donated. what happens |
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Definition
1. agglutination
2. hemolysis (from complement-mediated, opsonization)
3. clumped cells clog vessels of organs |
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Term
| whats the difference between PRBCS and whole blood |
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Definition
| PRBCs lacks the large amount of plasma in whole blood. Remember that anitbodies are in Plasma. |
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Term
| AB Antigens are only found on blood T/F |
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Definition
| False. They are found almost everywhere in the body |
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Term
| The most potent of the Rh Ag is |
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Definition
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Term
| Are more people Rh positive or negative |
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Definition
| 85% of people in US are Rh positive |
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Term
| Rh positive means you have what present |
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Definition
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Term
| are there more Rh antigenic sites or more A1 antigenic sites |
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Definition
| More A1 antigenic sites (1mil : 20,000) |
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Term
| If a person has Rh negative blood then they will not have a RhD on their RBC, but will they have Ab in the plasma? |
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Definition
| NO. Not unless they have been exposed to someone elses RhD. (transfusion, or pregnancy) |
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Term
| the most common and strongest of Rh antibodies is |
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Definition
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Term
| This antibody is present with much higher levels after 2nd exposure to Ag |
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Definition
| IgG is present in MUCH higher levels than IgM in second exposure reactions. IgG can cross placenta and kill baby. |
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Term
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Definition
| Is contains anti-RhD Ab that will give active immunity to mom who is Rh Negative to address the contamination of her blood during pregnancy by Rh positive child. |
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Term
| what is hemolytic disease of newborns |
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Definition
| Mom has anti-RhD antibodies and those cross placenta and destroys the RBCs of the fetus. |
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Term
| Sx of hemolytic disesase of a newborn |
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Definition
| more blue from destroyed RBCS from mom, IF severe baby is jaundiced becausre their immature livers can't keep up with byproducts of RBC lysis which is bilirubin. It becomes too much and toxic. |
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Term
| Maternal Anti-RhD Antibodies that enter the fetus can linger for how long |
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Definition
| 1-2 months; therefore causing prolonged hemolysis and disease to the feta RBC system |
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Term
| Most common to see ABO incompatibliity hemolyti disease in mothers who have Type _____ and babies who have ___ or ___ |
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Definition
| Moms with type O and babies with A or B |
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