Term
| The ability to sitmulate an immune response is called |
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Definition
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Term
| what is another name for an antigens which exhibits immunogenicity |
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Definition
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Term
| another name for a complete antigen |
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Definition
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Term
| the ability to bind with products of the immune response (antibody) but does not stimulate an immune response |
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Definition
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Term
| what type of antigens exhibit antigenicity |
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Definition
| incomplete antigens. So illicits antigenicity but not immunogenicity |
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Term
| small molecules that exhibit antigenicity but NO Immunogenicity are called |
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Definition
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Term
| does a hapten exhibit immunogenicity and antigenicity |
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Definition
| NO. Only exhibits antigenicity so it can bind to immune system componenets but will not illicit a response by itself unless it is with a carrier then together they may illicit a response. |
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Term
| the part on a complete antigen (immunogen) that is the specific piece that illicits a immune response is called |
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Definition
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Term
| another name for a antigenic determinate |
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Definition
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Term
| Can CD molecules have anitgenic detrminants? |
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Definition
| Yes and they may display immunogenic properties. |
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Term
| Give some examples of complete antigens |
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Definition
1. bacterial antigens
2. viral antigens
3. other microoragnisms
4. CD
5. MHC
6. Red blood cell antigens |
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Term
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Definition
| A hapten is a small molecule that can elicit an immune response only when attached to a large carrier such as a protein; the carrier may be one that also does not elicit an immune response by itself. |
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Term
| What is a complete antigen? what general characteristics makes a very strong immune provoking complete antigen. |
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Definition
| an antigen which can illicit an immune response is a complete antigen. The best characteristics of a complete antigen are as follows: 1. They are a protein or polysaccharide (not lipid or nucleic acid) 2. very foreign to the host's cells 3. molecular weight > 100,000 daltons 4. aromatic amino acids 5. more complex structure the better 6. L better than D amino acids 7. Large insoluble molecules are more immunogenic So does not HAVE to be the above. But if they are those then better and stronger the immunogenicity |
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Term
| substances used to increase immune response are known as |
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Definition
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Term
| how do B cells recognize antigenic determinatns |
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Definition
| by their 3 dimensional shape |
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Term
| Does B cells or T cells' Anttigen binding pocket completely fit the antigenic determinant |
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Definition
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Term
| T cells recognize what about foreign invaders |
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Definition
| recognizes the antigenic PEPTIDE ASSOCIATED with MHC I or MHC II through their TCR |
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Term
| What parts / quality of antigens do T cells recognize |
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Definition
1. internal portions
2. denatured
3. mostly proteins, some lipids and glycolipids attached to CD1 (Similar to MHC) |
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Term
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Definition
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Term
| what three common features of bacteria can be antigenic to our immune system |
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Definition
| 1. cell wall 2. capsule 3. other bacterial Ag characterisitcs / components |
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Term
| Describe function and characteristics of Interferon Gamma |
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Definition
| A type of cytokine with proinflammatory and proimmune response stimulation. It can stimulate macrophages and increase Affinity of E selectin on the endothelium. It is found in NK cells and NKT in the innate response. secreted also by T cells. |
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Term
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Definition
| a single organism composed of genetically distinct cells. Another way that chimerism can occur in animals is by organ transplantation, giving one individual tissues that developed from two different genomes. For example, a bone marrow transplant can change someone's blood type. |
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